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Items: 1 to 20 of 314

1.

Mapping the rho1 GABA(C) receptor agonist binding pocket. Constructing a complete model.

Sedelnikova A, Smith CD, Zakharkin SO, Davis D, Weiss DS, Chang Y.

J Biol Chem. 2005 Jan 14;280(2):1535-42. Epub 2004 Nov 17.

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Molecular modeling of ligand-receptor interactions in GABA C receptor.

Osolodkin DI, Chupakhin VI, Palyulin VA, Zefirov NS.

J Mol Graph Model. 2009 Apr;27(7):813-21. doi: 10.1016/j.jmgm.2008.12.004. Epub 2008 Dec 24.

PMID:
19167917
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A molecular basis for agonist and antagonist actions at GABA(C) receptors.

Abdel-Halim H, Hanrahan JR, Hibbs DE, Johnston GA, Chebib M.

Chem Biol Drug Des. 2008 Apr;71(4):306-27. doi: 10.1111/j.1747-0285.2008.00642.x. Epub 2008 Feb 28.

PMID:
18312293
6.

Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

Boileau AJ, Evers AR, Davis AF, Czajkowski C.

J Neurosci. 1999 Jun 15;19(12):4847-54.

8.

Structural determinants for antagonist pharmacology that distinguish the rho1 GABAC receptor from GABAA receptors.

Zhang J, Xue F, Chang Y.

Mol Pharmacol. 2008 Oct;74(4):941-51. doi: 10.1124/mol.108.048710. Epub 2008 Jul 3.

9.

5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.

Madsen C, Jensen AA, Liljefors T, Kristiansen U, Nielsen B, Hansen CP, Larsen M, Ebert B, Bang-Andersen B, Krogsgaard-Larsen P, Frølund B.

J Med Chem. 2007 Aug 23;50(17):4147-61. Epub 2007 Jul 26.

PMID:
17655213
10.

Four amino acids in the alpha subunits determine the gamma-aminobutyric acid sensitivities of GABAA receptor subtypes.

Böhme I, Rabe H, Lüddens H.

J Biol Chem. 2004 Aug 20;279(34):35193-200. Epub 2004 Jun 15.

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Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.

Carland JE, Moorhouse AJ, Barry PH, Johnston GA, Chebib M.

J Biol Chem. 2004 Dec 24;279(52):54153-60. Epub 2004 Oct 14.

16.

Evidence that the TM1-TM2 loop contributes to the rho1 GABA receptor pore.

Filippova N, Wotring VE, Weiss DS.

J Biol Chem. 2004 May 14;279(20):20906-14. Epub 2004 Mar 8.

17.

Structural rearrangements in loop F of the GABA receptor signal ligand binding, not channel activation.

Khatri A, Sedelnikova A, Weiss DS.

Biophys J. 2009 Jan;96(1):45-55. doi: 10.1016/j.bpj.2008.09.011.

20.

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