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The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling.

Sole C, Dolcet X, Segura MF, Gutierrez H, Diaz-Meco MT, Gozzelino R, Sanchis D, Bayascas JR, Gallego C, Moscat J, Davies AM, Comella JX.

J Cell Biol. 2004 Nov 8;167(3):479-92. Epub 2004 Nov 1.


The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010.


Mechanisms controlling neurite outgrowth in a pheochromocytoma cell line: the role of TRPC channels.

Kumar S, Chakraborty S, Barbosa C, Brustovetsky T, Brustovetsky N, Obukhov AG.

J Cell Physiol. 2012 Apr;227(4):1408-19. doi: 10.1002/jcp.22855.


The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.

Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2007 Oct 17;27(42):11228-41.


MAGI-1 acts as a scaffolding molecule for NGF receptor-mediated signaling pathway.

Ito H, Morishita R, Iwamoto I, Mizuno M, Nagata K.

Biochim Biophys Acta. 2013 Oct;1833(10):2302-10. doi: 10.1016/j.bbamcr.2013.06.005. Epub 2013 Jun 13.


NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells.

Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC.

J Neurosci. 2000 Oct 15;20(20):7556-63.


Inhibition of nerve growth factor-induced neurite outgrowth from PC12 cells by dexamethasone: signaling pathways through the glucocorticoid receptor and phosphorylated Akt and ERK1/2.

Terada K, Kojima Y, Watanabe T, Izumo N, Chiba K, Karube Y.

PLoS One. 2014 Mar 25;9(3):e93223. doi: 10.1371/journal.pone.0093223. eCollection 2014.


Neurotrophic factor-α1 modulates NGF-induced neurite outgrowth through interaction with Wnt-3a and Wnt-5a in PC12 cells and cortical neurons.

Selvaraj P, Huang JS, Chen A, Skalka N, Rosin-Arbesfeld R, Loh YP.

Mol Cell Neurosci. 2015 Sep;68:222-33. doi: 10.1016/j.mcn.2015.08.005. Epub 2015 Aug 11.


Identification and characterization of new isoforms of human fas apoptotic inhibitory molecule (FAIM).

Coccia E, Calleja-Yagüe I, Planells-Ferrer L, Sanuy B, Sanz B, López-Soriano J, Moubarak RS, Munell F, Barneda-Zahonero B, Comella JX, Pérez-García MJ.

PLoS One. 2017 Oct 5;12(10):e0185327. doi: 10.1371/journal.pone.0185327. eCollection 2017.


Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells.

Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Müller-Esterl W, Zeuzem S.

J Biol Chem. 2002 Nov 15;277(46):43623-30. Epub 2002 Sep 5.


p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones.

Bui NT, König HG, Culmsee C, Bauerbach E, Poppe M, Krieglstein J, Prehn JH.

J Neurochem. 2002 May;81(3):594-605.


Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac.

Talebian A, Robinson-Brookes K, MacDonald JI, Meakin SO.

J Mol Neurosci. 2013 Jan;49(1):38-51. doi: 10.1007/s12031-012-9847-9. Epub 2012 Jun 29.


The p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cells.

Brynczka C, Merrick BA.

Differentiation. 2008 Sep;76(7):795-808. doi: 10.1111/j.1432-0436.2007.00261.x. Epub 2008 Jan 3.


Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth.

Wang L, Li S, Jungalwala FB.

J Neurosci Res. 2008 May 1;86(6):1254-66.


Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons.

Cohen MR, Johnson WM, Pilat JM, Kiselar J, DeFrancesco-Lisowitz A, Zigmond RE, Moiseenkova-Bell VY.

Mol Cell Biol. 2015 Dec;35(24):4238-52. doi: 10.1128/MCB.00549-15. Epub 2015 Sep 28.

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