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Items: 1 to 20 of 883

2.

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

Komuro A, Imamura T, Saitoh M, Yoshida Y, Yamori T, Miyazono K, Miyazawa K.

Oncogene. 2004 Sep 9;23(41):6914-23.

PMID:
15221015
3.

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.

Morén A, Imamura T, Miyazono K, Heldin CH, Moustakas A.

J Biol Chem. 2005 Jun 10;280(23):22115-23. Epub 2005 Apr 6.

4.

Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.

Mazerbourg S, Klein C, Roh J, Kaivo-Oja N, Mottershead DG, Korchynskyi O, Ritvos O, Hsueh AJ.

Mol Endocrinol. 2004 Mar;18(3):653-65. Epub 2003 Dec 18.

PMID:
14684852
5.

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.

Seo SR, Lallemand F, Ferrand N, Pessah M, L'Hoste S, Camonis J, Atfi A.

EMBO J. 2004 Oct 1;23(19):3780-92. Epub 2004 Sep 9.

6.

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.

Hanyu A, Ishidou Y, Ebisawa T, Shimanuki T, Imamura T, Miyazono K.

J Cell Biol. 2001 Dec 10;155(6):1017-27. Epub 2001 Dec 10.

7.

Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN.

Mizuide M, Hara T, Furuya T, Takeda M, Kusanagi K, Inada Y, Mori M, Imamura T, Miyazawa K, Miyazono K.

J Biol Chem. 2003 Jan 3;278(1):531-6. Epub 2002 Nov 7.

8.

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification.

Sakou T, Onishi T, Yamamoto T, Nagamine T, Sampath Tk, Ten Dijke P.

J Bone Miner Res. 1999 Jul;14(7):1145-52.

9.

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.

Murakami G, Watabe T, Takaoka K, Miyazono K, Imamura T.

Mol Biol Cell. 2003 Jul;14(7):2809-17. Epub 2003 Apr 4.

10.

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation.

Bonni S, Wang HR, Causing CG, Kavsak P, Stroschein SL, Luo K, Wrana JL.

Nat Cell Biol. 2001 Jun;3(6):587-95.

PMID:
11389444
11.

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.

Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH.

Nature. 1999 Aug 12;400(6745):687-93.

PMID:
10458166
12.

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K.

J Biol Chem. 2001 Apr 20;276(16):12477-80. Epub 2001 Feb 13.

13.

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.

Nakano A, Koinuma D, Miyazawa K, Uchida T, Saitoh M, Kawabata M, Hanai J, Akiyama H, Abe M, Miyazono K, Matsumoto T, Imamura T.

J Biol Chem. 2009 Mar 6;284(10):6109-15. doi: 10.1074/jbc.M804659200. Epub 2009 Jan 4.

14.

CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation.

Xin H, Xu X, Li L, Ning H, Rong Y, Shang Y, Wang Y, Fu XY, Chang Z.

J Biol Chem. 2005 May 27;280(21):20842-50. Epub 2005 Mar 21.

15.

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.

Itoh F, Asao H, Sugamura K, Heldin CH, ten Dijke P, Itoh S.

EMBO J. 2001 Aug 1;20(15):4132-42.

16.
17.

The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling.

Wicks SJ, Haros K, Maillard M, Song L, Cohen RE, Dijke PT, Chantry A.

Oncogene. 2005 Dec 1;24(54):8080-4.

PMID:
16027725
18.

Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

Pardali K, Kowanetz M, Heldin CH, Moustakas A.

J Cell Physiol. 2005 Jul;204(1):260-72.

PMID:
15690394
19.

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.

Fukasawa H, Yamamoto T, Togawa A, Ohashi N, Fujigaki Y, Oda T, Uchida C, Kitagawa K, Hattori T, Suzuki S, Kitagawa M, Hishida A.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8687-92. Epub 2004 Jun 1.

20.

Phospho-Smad1 modulation by nedd4 E3 ligase in BMP/TGF-β signaling.

Kim BG, Lee JH, Yasuda J, Ryoo HM, Cho JY.

J Bone Miner Res. 2011 Jul;26(7):1411-24. doi: 10.1002/jbmr.348. Erratum in: J Bone Miner Res. 2012 Jun;27(6):1437.

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