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Items: 1 to 20 of 139

1.

Modulation of gene expression by tumor-derived p53 mutants.

Scian MJ, Stagliano KE, Ellis MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S.

Cancer Res. 2004 Oct 15;64(20):7447-54.

2.

Tumor-derived p53 mutants induce NF-kappaB2 gene expression.

Scian MJ, Stagliano KE, Anderson MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S.

Mol Cell Biol. 2005 Nov;25(22):10097-110.

3.

Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.

Yeudall WA, Vaughan CA, Miyazaki H, Ramamoorthy M, Choi MY, Chapman CG, Wang H, Black E, Bulysheva AA, Deb SP, Windle B, Deb S.

Carcinogenesis. 2012 Feb;33(2):442-51. doi: 10.1093/carcin/bgr270. Epub 2011 Nov 22.

PMID:
22114072
4.

Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.

Gu J, Zhang L, Swisher SG, Liu J, Roth JA, Fang B.

Oncogene. 2004 Feb 12;23(6):1300-7.

PMID:
14676844
5.

Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target.

Wu Q, Ding W, Mirza A, Van Arsdale T, Wei I, Bishop WR, Basso A, McClanahan T, Luo L, Kirschmeier P, Gustafson E, Hernandez M, Liu S.

J Biol Chem. 2005 Apr 1;280(13):12935-43. Epub 2005 Jan 18.

6.

AMPK-beta1 subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression.

Li J, Jiang P, Robinson M, Lawrence TS, Sun Y.

Carcinogenesis. 2003 May;24(5):827-34.

PMID:
12771025
9.

Transactivation of the EGR1 gene contributes to mutant p53 gain of function.

Weisz L, Zalcenstein A, Stambolsky P, Cohen Y, Goldfinger N, Oren M, Rotter V.

Cancer Res. 2004 Nov 15;64(22):8318-27.

10.

Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis.

Downing S, Bumak C, Nixdorf S, Ow K, Russell P, Jackson P.

Mol Carcinog. 2003 Nov;38(3):130-40.

PMID:
14587098
11.

WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells.

Cuddihy AR, Jalali F, Coackley C, Bristow RG.

Mol Cancer Ther. 2008 Apr;7(4):980-92. doi: 10.1158/1535-7163.MCT-07-0471.

12.

Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells.

Tepper CG, Gregg JP, Shi XB, Vinall RL, Baron CA, Ryan PE, Desprez PY, Kung HJ, deVere White RW.

Prostate. 2005 Dec 1;65(4):375-89.

PMID:
16037992
13.

p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo.

Katiyar SK, Meeran SM, Katiyar N, Akhtar S.

Mol Carcinog. 2009 Jan;48(1):24-37. doi: 10.1002/mc.20453.

PMID:
18459128
15.

Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants.

Deb D, Scian M, Roth KE, Li W, Keiger J, Chakraborti AS, Deb SP, Deb S.

Oncogene. 2002 Jan 10;21(2):176-89.

16.

In situ detection of unexpected patterns of mutant p53 gene expression in non-small cell lung cancers.

Ebina M, Martínez A, Birrer MJ, Ilona Linnoila R.

Oncogene. 2001 May 3;20(20):2579-86.

17.

Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53.

Vikhanskaya F, Lee MK, Mazzoletti M, Broggini M, Sabapathy K.

Nucleic Acids Res. 2007;35(6):2093-104. Epub 2007 Mar 7.

18.

Growth suppression mediated by transfection of p53 in Hut292DM human lung cancer cells expressing endogenous wild-type p53 protein.

Cajot JF, Anderson MJ, Lehman TA, Shapiro H, Briggs AA, Stanbridge EJ.

Cancer Res. 1992 Dec 15;52(24):6956-60.

19.

3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis.

Oh JJ, Razfar A, Delgado I, Reed RA, Malkina A, Boctor B, Slamon DJ.

Cancer Res. 2006 Apr 1;66(7):3419-27.

20.

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