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Items: 1 to 20 of 101

1.

TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma.

Tacconelli A, Farina AR, Cappabianca L, Desantis G, Tessitore A, Vetuschi A, Sferra R, Rucci N, Argenti B, Screpanti I, Gulino A, Mackay AR.

Cancer Cell. 2004 Oct;6(4):347-60.

2.

Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in neuroblastoma.

Tacconelli A, Farina AR, Cappabianca L, Gulino A, Mackay AR.

Future Oncol. 2005 Oct;1(5):689-98. Review.

PMID:
16556046
3.

Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells.

Eggert A, Ikegaki N, Liu X, Chou TT, Lee VM, Trojanowski JQ, Brodeur GM.

Oncogene. 2000 Apr 13;19(16):2043-51.

4.

TrkA signal transduction pathways in neuroblastoma.

Eggert A, Ikegaki N, Liu XG, Chou TT, Brodeur GM.

Med Pediatr Oncol. 2001 Jan;36(1):108-10.

PMID:
11464858
5.

The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.

Farina AR, Tacconelli A, Cappabianca L, Cea G, Chioda A, Romanelli A, Pensato S, Pedone C, Gulino A, Mackay AR.

Oncogene. 2009 Nov 19;28(46):4075-94. doi: 10.1038/onc.2009.256. Epub 2009 Sep 7.

PMID:
19734938
7.

TrkAIII. A novel hypoxia-regulated alternative TrkA splice variant of potential physiological and pathological importance.

Tacconelli A, Farina AR, Cappabianca L, Gulino A, Mackay AR.

Cell Cycle. 2005 Jan;4(1):8-9. Epub 2005 Jan 5.

PMID:
15611661
8.

TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype.

Farina AR, Di Ianni N, Cappabianca L, Ruggeri P, Ragone M, Ianni G, Gulino A, Mackay AR.

Biomed Res Int. 2013;2013:740187. doi: 10.1155/2013/740187. Epub 2013 Jun 6.

9.

The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.

Ruggeri P, Farina AR, Di Ianni N, Cappabianca L, Ragone M, Ianni G, Gulino A, Mackay AR.

PLoS One. 2014 Apr 15;9(4):e94568. doi: 10.1371/journal.pone.0094568. eCollection 2014.

10.

The alternative TrkAIII splice variant targets the centrosome and promotes genetic instability.

Farina AR, Tacconelli A, Cappabianca L, Cea G, Panella S, Chioda A, Romanelli A, Pedone C, Gulino A, Mackay AR.

Mol Cell Biol. 2009 Sep;29(17):4812-30. doi: 10.1128/MCB.00352-09. Epub 2009 Jun 29.

11.

Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity.

Farina AR, Cappabianca L, Ruggeri P, Gneo L, Maccarone R, Mackay AR.

Oncotarget. 2015 Nov 3;6(34):35636-51. doi: 10.18632/oncotarget.5802.

12.
13.

Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J.

Neuroscience. 2002;115(4):1089-108.

PMID:
12453482
14.

Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation.

Emdal KB, Pedersen AK, Bekker-Jensen DB, Tsafou KP, Horn H, Lindner S, Schulte JH, Eggert A, Jensen LJ, Francavilla C, Olsen JV.

Sci Signal. 2015 Apr 28;8(374):ra40. doi: 10.1126/scisignal.2005769.

PMID:
25921289
15.

Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.

Sugimoto T, Kuroda H, Horii Y, Moritake H, Tanaka T, Hattori S.

Jpn J Cancer Res. 2001 Feb;92(2):152-60.

PMID:
11223544
16.
17.
18.

Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis.

Peng X, Greene LA, Kaplan DR, Stephens RM.

Neuron. 1995 Aug;15(2):395-406.

20.

Functional expression of TrkA receptors in hippocampal neurons.

Aibel L, Martin-Zanca D, Perez P, Chao MV.

J Neurosci Res. 1998 Nov 1;54(3):424-31.

PMID:
9819147

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