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Innate immunity in experimental SIV infection and vaccination.

Ahmed RK, Biberfeld G, Thorstensson R.

Mol Immunol. 2005 Feb;42(2):251-8. Review.


The role of immunity in protection from mucosal SIV infection in macaques.

Bergmeier LA, Wang Y, Lehner T.

Oral Dis. 2002;8 Suppl 2:63-8. Review.


Protective mucosal immunity elicited by targeted lymph node immunization with a subunit SIV envelope and core vaccine in macaques.

Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Jones I, Doyle C.

Dev Biol Stand. 1998;92:225-35.


Reduction of viral loads by multigenic DNA priming and adenovirus boosting in the SIVmac-macaque model.

Suh YS, Park KS, Sauermann U, Franz M, Norley S, Wilfingseder D, Stoiber H, Fagrouch Z, Heeney J, Hunsmann G, Stahl-Hennig C, Sung YC.

Vaccine. 2006 Mar 10;24(11):1811-20. Epub 2005 Oct 25.


Evaluation of SIV-lipopeptide immunizations administered by the intradermal route in their ability to induce antigen specific T-cell responses in rhesus macaques.

Coutsinos Z, Villefroy P, Gras-Masse H, Guillet JG, Bourgault-Villada I.

FEMS Immunol Med Microbiol. 2005 Mar 1;43(3):357-66.


A rational basis for mucosal vaccination against HIV infection.

Lehner T, Bergmeier L, Wang Y, Tao L, Mitchell E.

Immunol Rev. 1999 Aug;170:183-96. Review.


Rapid virus dissemination in infant macaques after oral simian immunodeficiency virus exposure in the presence of local innate immune responses.

Abel K, Pahar B, Van Rompay KK, Fritts L, Sin C, Schmidt K, Colón R, McChesney M, Marthas ML.

J Virol. 2006 Jul;80(13):6357-67.


Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination.

Velu V, Kannanganat S, Ibegbu C, Chennareddi L, Villinger F, Freeman GJ, Ahmed R, Amara RR.

J Virol. 2007 Jun;81(11):5819-28. Epub 2007 Mar 21.


Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responses.

Malkevitch NV, Patterson LJ, Aldrich MK, Wu Y, Venzon D, Florese RH, Kalyanaraman VS, Pal R, Lee EM, Zhao J, Cristillo A, Robert-Guroff M.

Virology. 2006 Sep 15;353(1):83-98. Epub 2006 Jun 30.


Effect of therapeutic immunization using Ad5/35 and MVA vectors on SIV infection of rhesus monkeys undergoing antiretroviral therapy.

Shimada M, Wang HB, Kondo A, Xu XP, Yoshida A, Shinoda K, Ura T, Mizuguchi H, Klinman D, Luo JL, Bai H, Okuda K.

Gene Ther. 2009 Feb;16(2):218-28. doi: 10.1038/gt.2008.152. Epub 2008 Oct 16.


Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.

Engram JC, Dunham RM, Makedonas G, Vanderford TH, Sumpter B, Klatt NR, Ratcliffe SJ, Garg S, Paiardini M, McQuoid M, Altman JD, Staprans SI, Betts MR, Garber DA, Feinberg MB, Silvestri G.

J Immunol. 2009 Jul 1;183(1):706-17. doi: 10.4049/jimmunol.0803746.


Enhanced antibody responses elicited by a CpG adjuvant do not improve the protective effect of an aldrithiol-2-inactivated simian immunodeficiency virus therapeutic AIDS vaccine.

Wang Y, Blozis SA, Lederman M, Krieg A, Landay A, Miller CJ.

Clin Vaccine Immunol. 2009 Apr;16(4):499-505. doi: 10.1128/CVI.00471-08. Epub 2009 Feb 18.


CCR5 targeted SIV vaccination strategy preventing or inhibiting SIV infection.

Bogers WM, Bergmeier LA, Oostermeijer H, ten Haaft P, Wang Y, Kelly CG, Singh M, Heeney JL, Lehner T.

Vaccine. 2004 Aug 13;22(23-24):2974-84.


Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques.

Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R.

Nat Med. 1996 Jul;2(7):767-75.


Innate anti-viral immunity is associated with the protection elicited by the simian immunodeficiency virus (SIV) live attenuated virus vaccine in cynomolgus monkeys.

Goletti D, Macchia I, Leone P, Pace M, Sernicola L, Pavone-Cossut MR, Maggiorella MT, Cafaro A, Ensoli B, Titti F.

Med Sci Monit. 2006 Oct;12(10):BR330-40. Epub 2006 Sep 25.


Contrasting effects of low-dose IL-2 on vaccine-boosted simian immunodeficiency virus (SIV)-specific CD4+ and CD8+ T cells in macaques chronically infected with SIVmac251.

Nacsa J, Edghill-Smith Y, Tsai WP, Venzon D, Tryniszewska E, Hryniewicz A, Moniuszko M, Kinter A, Smith KA, Franchini G.

J Immunol. 2005 Feb 15;174(4):1913-21.


Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques.

Metzner KJ, Binley JM, Gettie A, Marx P, Nixon DF, Connor RI.

Retrovirology. 2006 Dec 21;3:97.


Immunity in natural SIV infections.

Silvestri G.

J Intern Med. 2009 Jan;265(1):97-109. doi: 10.1111/j.1365-2796.2008.02049.x. Review.

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