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Items: 1 to 20 of 68

1.
2.

Fas ligand (CD178) cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity.

Jodo S, Pidiyar VJ, Xiao S, Furusaki A, Sharma R, Koike T, Ju ST.

J Immunol. 2005 Apr 15;174(8):4470-4.

3.

Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail.

Blott EJ, Bossi G, Clark R, Zvelebil M, Griffiths GM.

J Cell Sci. 2001 Jul;114(Pt 13):2405-16.

4.

Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.

Baum W, Kirkin V, Fernández SB, Pick R, Lettau M, Janssen O, Zörnig M.

J Biol Chem. 2005 Dec 2;280(48):40012-24. Epub 2005 Oct 4.

5.

The adaptor protein Grb2 regulates cell surface Fas ligand in Schwann cells.

Thornhill PB, Cohn JB, Stanford WL, Desbarats J.

Biochem Biophys Res Commun. 2008 Nov 14;376(2):341-6. doi: 10.1016/j.bbrc.2008.08.164. Epub 2008 Sep 16.

PMID:
18789888
6.

Separate domains of the human fas ligand dictate self-association and receptor binding.

Orlinick JR, Elkon KB, Chao MV.

J Biol Chem. 1997 Dec 19;272(51):32221-9.

7.

The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse.

Lettau M, Qian J, Linkermann A, Latreille M, Larose L, Kabelitz D, Janssen O.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5911-6. Epub 2006 Apr 4.

8.

Fas-ligand is stored in secretory lysosomes of ocular barrier epithelia and released with microvesicles.

McKechnie NM, King BC, Fletcher E, Braun G.

Exp Eye Res. 2006 Aug;83(2):304-14. Epub 2006 Mar 24.

PMID:
16563377
9.

Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL.

Qian J, Chen W, Lettau M, Podda G, Zörnig M, Kabelitz D, Janssen O.

Cell Signal. 2006 Aug;18(8):1327-37. Epub 2005 Nov 28.

PMID:
16318909
10.

Molecular cloning, expression and characterization of rhesus macaque Fas ligand cDNA.

Wang W, Asiedu C, George JF, Thomas JM.

Hum Immunol. 1998 Oct;59(10):599-606.

PMID:
9757941
11.

Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation.

Zuccato E, Blott EJ, Holt O, Sigismund S, Shaw M, Bossi G, Griffiths GM.

J Cell Sci. 2007 Jan 1;120(Pt 1):191-9. Epub 2006 Dec 12.

12.

Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells.

De Paepe ME, Mao Q, Chao Y, Powell JL, Rubin LP, Sharma S.

Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L647-59.

13.
14.

CTLs contain and use intracellular stores of FasL distinct from cytolytic granules.

He JS, Ostergaard HL.

J Immunol. 2007 Aug 15;179(4):2339-48.

15.

Augmentation of Fas ligand-induced apoptosis by MUC1 mucin.

Chaturvedi R, Srivastava RK, Hisatsune A, Shankar S, Lillehoj EP, Kim KC.

Int J Oncol. 2005 May;26(5):1169-76.

PMID:
15809706
16.

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability.

Henkler F, Behrle E, Dennehy KM, Wicovsky A, Peters N, Warnke C, Pfizenmaier K, Wajant H.

J Cell Biol. 2005 Mar 28;168(7):1087-98.

17.

Mechanism of nuclear factor of activated T-cells mediated FasL expression in corticosterone -treated mouse Leydig tumor cells.

Chai WR, Chen Y, Wang Q, Gao HB.

BMC Cell Biol. 2008 Jun 12;9:31. doi: 10.1186/1471-2121-9-31.

18.

A homozygous Fas ligand gene mutation in a patient causes a new type of autoimmune lymphoproliferative syndrome.

Del-Rey M, Ruiz-Contreras J, Bosque A, Calleja S, Gomez-Rial J, Roldan E, Morales P, Serrano A, Anel A, Paz-Artal E, Allende LM.

Blood. 2006 Aug 15;108(4):1306-12. Epub 2006 Apr 20.

19.

Involvement of the TNF-alpha autocrine-paracrine loop, via NF-kappaB and YY1, in the regulation of tumor cell resistance to Fas-induced apoptosis.

Huerta-Yepez S, Vega M, Garban H, Bonavida B.

Clin Immunol. 2006 Sep;120(3):297-309. Epub 2006 Jun 19.

PMID:
16784892
20.

FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.

Beier CP, Wischhusen J, Gleichmann M, Gerhardt E, Pekanovic A, Krueger A, Taylor V, Suter U, Krammer PH, Endres M, Weller M, Schulz JB.

J Neurosci. 2005 Jul 20;25(29):6765-74.

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