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Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.

Krause M, Leslie JD, Stewart M, Lafuente EM, Valderrama F, Jagannathan R, Strasser GA, Rubinson DA, Liu H, Way M, Yaffe MB, Boussiotis VA, Gertler FB.

Dev Cell. 2004 Oct;7(4):571-83.


A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex.

Yoshinaga S, Ohkubo T, Sasaki S, Nuriya M, Ogawa Y, Yasui M, Tabata H, Nakajima K.

J Neurosci. 2012 Aug 22;32(34):11643-56. doi: 10.1523/JNEUROSCI.0738-12.2012.


RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.

Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, Constantine E, Springer TA, Gertler FB, Boussiotis VA.

Dev Cell. 2004 Oct;7(4):585-95.


Ena/VASP family: new partners, bigger enigma.

Bailly M.

Dev Cell. 2004 Oct;7(4):462-3.


Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.

Lebrand C, Dent EW, Strasser GA, Lanier LM, Krause M, Svitkina TM, Borisy GG, Gertler FB.

Neuron. 2004 Apr 8;42(1):37-49.


High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP.

Kursula P, Kursula I, Massimi M, Song YH, Downer J, Stanley WA, Witke W, Wilmanns M.

J Mol Biol. 2008 Jan 4;375(1):270-90. Epub 2007 Oct 24.


Modulation of lamellipodial structure and dynamics by NO-dependent phosphorylation of VASP Ser239.

Lindsay SL, Ramsey S, Aitchison M, Renné T, Evans TJ.

J Cell Sci. 2007 Sep 1;120(Pt 17):3011-21. Epub 2007 Aug 7.


cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains.

Lambrechts A, Kwiatkowski AV, Lanier LM, Bear JE, Vandekerckhove J, Ampe C, Gertler FB.

J Biol Chem. 2000 Nov 17;275(46):36143-51.


PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE.

FEBS Lett. 2006 May 22;580(12):455-63.


PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE.

FEBS Lett. 2005 Jan 17;579(2):455-63.


Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.

Coppolino MG, Krause M, Hagendorff P, Monner DA, Trimble W, Grinstein S, Wehland J, Sechi AS.

J Cell Sci. 2001 Dec;114(Pt 23):4307-18.


Ena/VASP proteins have an anti-capping independent function in filopodia formation.

Applewhite DA, Barzik M, Kojima S, Svitkina TM, Gertler FB, Borisy GG.

Mol Biol Cell. 2007 Jul;18(7):2579-91. Epub 2007 May 2.


Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility.

Bear JE, Svitkina TM, Krause M, Schafer DA, Loureiro JJ, Strasser GA, Maly IV, Chaga OY, Cooper JA, Borisy GG, Gertler FB.

Cell. 2002 May 17;109(4):509-21.


The state of the actin cytoskeleton determines its association with gephyrin: role of ena/VASP family members.

Bausen M, Fuhrmann JC, Betz H, O'sullivan GA.

Mol Cell Neurosci. 2006 Feb;31(2):376-86. Epub 2006 Jan 11.


Loss of profilin-1 expression enhances breast cancer cell motility by Ena/VASP proteins.

Bae YH, Ding Z, Zou L, Wells A, Gertler F, Roy P.

J Cell Physiol. 2009 May;219(2):354-64. doi: 10.1002/jcp.21677.

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