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Items: 1 to 20 of 124

1.

Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function.

Tang Q, Boden EK, Henriksen KJ, Bour-Jordan H, Bi M, Bluestone JA.

Eur J Immunol. 2004 Nov;34(11):2996-3005.

2.

CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4.

Kataoka H, Takahashi S, Takase K, Yamasaki S, Yokosuka T, Koike T, Saito T.

Int Immunol. 2005 Apr;17(4):421-7.

PMID:
15724061
3.

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.

Kullberg MC, Hay V, Cheever AW, Mamura M, Sher A, Letterio JJ, Shevach EM, Piccirillo CA.

Eur J Immunol. 2005 Oct;35(10):2886-95.

4.

TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells.

Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA.

J Immunol. 2006 Mar 15;176(6):3321-9.

5.
6.

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness.

Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, Mizuhara H, Shevach EM.

J Exp Med. 2002 Jul 15;196(2):237-46.

7.

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.

Sugita S, Horie S, Nakamura O, Maruyama K, Takase H, Usui Y, Takeuchi M, Ishidoh K, Koike M, Uchiyama Y, Peters C, Yamamoto Y, Mochizuki M.

J Immunol. 2009 Oct 15;183(8):5013-22. doi: 10.4049/jimmunol.0901623.

8.

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling.

Oida T, Xu L, Weiner HL, Kitani A, Strober W.

J Immunol. 2006 Aug 15;177(4):2331-9.

9.

Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity.

Tsaknaridis L, Spencer L, Culbertson N, Hicks K, LaTocha D, Chou YK, Whitham RH, Bakke A, Jones RE, Offner H, Bourdette DN, Vandenbark AA.

J Neurosci Res. 2003 Oct 15;74(2):296-308.

PMID:
14515359
10.

CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity.

Bianchini R, Bistoni O, Alunno A, Petrillo MG, Ronchetti S, Sportoletti P, Bocci EB, Nocentini G, Gerli R, Riccardi C.

Eur J Immunol. 2011 Aug;41(8):2269-78. doi: 10.1002/eji.201040943.

11.
12.

CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice.

Kolar P, Knieke K, Hegel JK, Quandt D, Burmester GR, Hoff H, Brunner-Weinzierl MC.

Arthritis Rheum. 2009 Jan;60(1):123-32. doi: 10.1002/art.24181.

13.

CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes.

Green EA, Gorelik L, McGregor CM, Tran EH, Flavell RA.

Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10878-83.

16.

Retinal pigment epithelium-derived CTLA-2alpha induces TGFbeta-producing T regulatory cells.

Sugita S, Horie S, Nakamura O, Futagami Y, Takase H, Keino H, Aburatani H, Katunuma N, Ishidoh K, Yamamoto Y, Mochizuki M.

J Immunol. 2008 Dec 1;181(11):7525-36.

17.

Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells.

Huber S, Schramm C, Lehr HA, Mann A, Schmitt S, Becker C, Protschka M, Galle PR, Neurath MF, Blessing M.

J Immunol. 2004 Dec 1;173(11):6526-31.

18.

Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE.

Liu Y, Teige I, Birnir B, Issazadeh-Navikas S.

Nat Med. 2006 May;12(5):518-25.

PMID:
16633347
19.

Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells.

Li R, Perez N, Karumuthil-Melethil S, Prabhakar BS, Holterman MJ, Vasu C.

J Immunol. 2007 Oct 15;179(8):5191-203.

20.

Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells.

Takeda I, Ine S, Killeen N, Ndhlovu LC, Murata K, Satomi S, Sugamura K, Ishii N.

J Immunol. 2004 Mar 15;172(6):3580-9.

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