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Items: 1 to 20 of 101

1.

GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.

Cole AR, Knebel A, Morrice NA, Robertson LA, Irving AJ, Connolly CN, Sutherland C.

J Biol Chem. 2004 Nov 26;279(48):50176-80. Epub 2004 Oct 5.

2.

GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K.

Cell. 2005 Jan 14;120(1):137-49.

3.

GSK-3 mediates the okadaic acid-induced modification of collapsin response mediator protein-2 in human SK-N-SH neuroblastoma cells.

Ni MH, Wu CC, Chan WH, Chien KY, Yu JS.

J Cell Biochem. 2008 Apr 15;103(6):1833-48.

PMID:
17902168
4.

Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease.

Uchida Y, Ohshima T, Sasaki Y, Suzuki H, Yanai S, Yamashita N, Nakamura F, Takei K, Ihara Y, Mikoshiba K, Kolattukudy P, Honnorat J, Goshima Y.

Genes Cells. 2005 Feb;10(2):165-79.

5.

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.

Cole AR, Causeret F, Yadirgi G, Hastie CJ, McLauchlan H, McManus EJ, Hernández F, Eickholt BJ, Nikolic M, Sutherland C.

J Biol Chem. 2006 Jun 16;281(24):16591-8. Epub 2006 Apr 12.

6.

Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity.

Fang W, Gao G, Zhao H, Xia Y, Guo X, Li N, Li Y, Yang Y, Chen L, Wang Q, Li L.

Brain Res. 2015 Mar 30;1602:9-19. doi: 10.1016/j.brainres.2014.08.030. Epub 2014 Aug 21.

PMID:
25150591
7.

Involvement of the Akt/GSK-3β/CRMP-2 pathway in axonal injury after hypoxic-ischemic brain damage in neonatal rat.

Xiong T, Tang J, Zhao J, Chen H, Zhao F, Li J, Qu Y, Ferriero D, Mu D.

Neuroscience. 2012 Aug 2;216:123-32. doi: 10.1016/j.neuroscience.2012.04.052. Epub 2012 Apr 30.

PMID:
22554777
8.

[Molecular mechanisms of neuronal polarity].

Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kaibuchi K.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2005 Aug;25(4):169-74. Review. Japanese.

PMID:
16190365
9.

CRMP-2 is involved in axon growth inhibition induced by RGMa in vitro and in vivo.

Wang T, Wu X, Yin C, Klebe D, Zhang JH, Qin X.

Mol Neurobiol. 2013 Jun;47(3):903-13. doi: 10.1007/s12035-012-8385-3. Epub 2012 Dec 30.

PMID:
23275173
10.

GSK-3α/β-mediated phosphorylation of CRMP-2 regulates activity-dependent dendritic growth.

Tan M, Ma S, Huang Q, Hu K, Song B, Li M.

J Neurochem. 2013 Jun;125(5):685-97. doi: 10.1111/jnc.12230. Epub 2013 Mar 25.

11.

Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway.

Yoshimura T, Arimura N, Kawano Y, Kawabata S, Wang S, Kaibuchi K.

Biochem Biophys Res Commun. 2006 Feb 3;340(1):62-8. Epub 2005 Dec 6.

PMID:
16343426
12.

Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse.

Brown M, Jacobs T, Eickholt B, Ferrari G, Teo M, Monfries C, Qi RZ, Leung T, Lim L, Hall C.

J Neurosci. 2004 Oct 13;24(41):8994-9004.

13.

Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.

Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, Richardson JC, Yan SD, Hanger DP, Allan SM, Sutherland C.

J Neurochem. 2007 Nov;103(3):1132-44. Epub 2007 Aug 7.

14.

Molecular mechanisms of axon specification and neuronal disorders.

Yoshimura T, Arimura N, Kaibuchi K.

Ann N Y Acad Sci. 2006 Nov;1086:116-25. Review.

PMID:
17185510
15.

Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.

Uchida Y, Ohshima T, Yamashita N, Ogawara M, Sasaki Y, Nakamura F, Goshima Y.

J Biol Chem. 2009 Oct 2;284(40):27393-401. doi: 10.1074/jbc.M109.000240. Epub 2009 Aug 3.

16.
17.

Targeting of CRMP-2 to the primary cilium is modulated by GSK-3β.

Ou Y, Zhang Y, Cheng M, Rattner JB, Dobrinski I, van der Hoorn FA.

PLoS One. 2012;7(11):e48773. doi: 10.1371/journal.pone.0048773. Epub 2012 Nov 21.

18.

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.

Moutal A, François-Moutal L, Perez-Miller S, Cottier K, Chew LA, Yeon SK, Dai J, Park KD, Khanna M, Khanna R.

Mol Neurobiol. 2016 Apr;53(3):1959-1976. doi: 10.1007/s12035-015-9141-2. Epub 2015 Apr 7.

PMID:
25846820
19.

Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation.

Cole AR, Soutar MP, Rembutsu M, van Aalten L, Hastie CJ, McLauchlan H, Peggie M, Balastik M, Lu KP, Sutherland C.

J Biol Chem. 2008 Jun 27;283(26):18227-37. doi: 10.1074/jbc.M801645200. Epub 2008 May 6.

20.

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