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Items: 1 to 20 of 2270

1.

Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models.

Götz J, Schild A, Hoerndli F, Pennanen L.

Int J Dev Neurosci. 2004 Nov;22(7):453-65. Review.

PMID:
15465275
2.

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I.

J Neurosci. 2010 Jul 7;30(27):9228-40. doi: 10.1523/JNEUROSCI.0418-10.2010.

3.

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E.

Science. 2001 Aug 24;293(5534):1487-91.

4.

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.

Ribé EM, Pérez M, Puig B, Gich I, Lim F, Cuadrado M, Sesma T, Catena S, Sánchez B, Nieto M, Gómez-Ramos P, Morán MA, Cabodevilla F, Samaranch L, Ortiz L, Pérez A, Ferrer I, Avila J, Gómez-Isla T.

Neurobiol Dis. 2005 Dec;20(3):814-22. Epub 2005 Aug 24.

PMID:
16125396
5.

The molecular bases of Alzheimer's disease and other neurodegenerative disorders.

Maccioni RB, Muñoz JP, Barbeito L.

Arch Med Res. 2001 Sep-Oct;32(5):367-81. Review.

PMID:
11578751
6.

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM.

Neurobiol Aging. 2003 Dec;24(8):1063-70.

PMID:
14643377
7.

[Alzheimer disease: cellular and molecular aspects].

Octave JN.

Bull Mem Acad R Med Belg. 2005;160(10-12):445-9; discussion 450-1. French.

PMID:
16768248
8.

Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.

Grueninger F, Bohrmann B, Czech C, Ballard TM, Frey JR, Weidensteiner C, von Kienlin M, Ozmen L.

Neurobiol Dis. 2010 Feb;37(2):294-306. doi: 10.1016/j.nbd.2009.09.004. Epub 2009 Sep 23.

PMID:
19781645
9.

Plaques, tangles, and memory loss in mouse models of neurodegeneration.

Eriksen JL, Janus CG.

Behav Genet. 2007 Jan;37(1):79-100. Epub 2006 Oct 28. Review.

PMID:
17072762
10.

Mouse models of Alzheimer's disease: insight into treatment.

German DC, Eisch AJ.

Rev Neurosci. 2004;15(5):353-69. Review.

PMID:
15575491
11.

Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.

Guix FX, Ill-Raga G, Bravo R, Nakaya T, de Fabritiis G, Coma M, Miscione GP, Villà-Freixa J, Suzuki T, Fernàndez-Busquets X, Valverde MA, de Strooper B, Muñoz FJ.

Brain. 2009 May;132(Pt 5):1335-45. doi: 10.1093/brain/awp023. Epub 2009 Feb 27.

PMID:
19251756
12.

Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1.

Boutajangout A, Authelet M, Blanchard V, Touchet N, Tremp G, Pradier L, Brion JP.

Neurobiol Dis. 2004 Feb;15(1):47-60.

PMID:
14751770
13.

A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition.

Flood DG, Lin YG, Lang DM, Trusko SP, Hirsch JD, Savage MJ, Scott RW, Howland DS.

Neurobiol Aging. 2009 Jul;30(7):1078-90. Epub 2007 Nov 28.

PMID:
18053619
14.

Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.

Shin RW, Ogino K, Shimabuku A, Taki T, Nakashima H, Ishihara T, Kitamoto T.

Acta Neuropathol. 2007 Jun;113(6):627-36. Epub 2007 Mar 13.

PMID:
17431643
15.

[The lesions of Alzheimer's disease: which therapeutic perspectives?].

Duyckaerts C, Perruchini C, Lebouvier T, Potier MC.

Bull Acad Natl Med. 2008 Feb;192(2):303-18; discussion 318-21. Review. French.

PMID:
18819685
16.

Tau and transgenic animal models.

Götz J.

Brain Res Brain Res Rev. 2001 Jul;35(3):266-86. Review.

PMID:
11423157
17.

[Alzheimer's disease: lesions and their progression].

Duyckaerts C, Colle MA, Delatour B, Hauw JJ.

Rev Neurol (Paris). 1999;155 Suppl 4:S17-27. Review. French.

PMID:
10637934
18.

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models.

Zhang Q, Zhang X, Sun A.

Acta Neuropathol. 2009 Jun;117(6):687-97. doi: 10.1007/s00401-009-0491-6. Epub 2009 Feb 4.

PMID:
19190923
19.

Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.

Padmanabhan J, Levy M, Dickson DW, Potter H.

Brain. 2006 Nov;129(Pt 11):3020-34. Epub 2006 Sep 20.

PMID:
16987932
20.

The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.

Gómez-Isla T, Growdon WB, McNamara MJ, Nochlin D, Bird TD, Arango JC, Lopera F, Kosik KS, Lantos PL, Cairns NJ, Hyman BT.

Brain. 1999 Sep;122 ( Pt 9):1709-19.

PMID:
10468510

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