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Items: 1 to 20 of 116

1.

Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteins.

Fischer SF, Vier J, Kirschnek S, Klos A, Hess S, Ying S, Häcker G.

J Exp Med. 2004 Oct 4;200(7):905-16. Epub 2004 Sep 27.

2.
3.

Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells.

Dong F, Pirbhai M, Xiao Y, Zhong Y, Wu Y, Zhong G.

Infect Immun. 2005 Mar;73(3):1861-4. Erratum in: Infect Immun. 2005 Jul;73(7):4459.

4.

The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.

Nikrad M, Johnson T, Puthalalath H, Coultas L, Adams J, Kraft AS.

Mol Cancer Ther. 2005 Mar;4(3):443-9.

5.

Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.

Ying S, Pettengill M, Latham ER, Walch A, Ojcius DM, Häcker G.

J Infect Dis. 2008 Nov 15;198(10):1536-44. doi: 10.1086/592755.

PMID:
18821848
6.

Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.

Zantl N, Weirich G, Zall H, Seiffert BM, Fischer SF, Kirschnek S, Hartmann C, Fritsch RM, Gillissen B, Daniel PT, Häcker G.

Oncogene. 2007 Oct 25;26(49):7038-48. Epub 2007 May 7.

PMID:
17486061
7.

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.

Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.

Mol Cell. 2001 Sep;8(3):705-11.

8.

Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent Phenoxodiol-induced apoptosis of human melanoma cells.

Yu F, Watts RN, Zhang XD, Borrow JM, Hersey P.

Anticancer Drugs. 2006 Nov;17(10):1151-61.

PMID:
17075314
9.

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

Luciano F, Jacquel A, Colosetti P, Herrant M, Cagnol S, Pages G, Auberger P.

Oncogene. 2003 Oct 2;22(43):6785-93.

PMID:
14555991
10.
11.

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

Herrant M, Jacquel A, Marchetti S, Belhacène N, Colosetti P, Luciano F, Auberger P.

Oncogene. 2004 Oct 14;23(47):7863-73.

PMID:
15378010
12.

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak.

Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB.

Genes Dev. 2001 Jun 15;15(12):1481-6.

13.

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family.

U M, Miyashita T, Shikama Y, Tadokoro K, Yamada M.

FEBS Lett. 2001 Nov 30;509(1):135-41.

14.

Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo.

Tsuchiya T, Bonner HP, Engel T, Woods I, Matsushima S, Ward MW, Taki W, Henshall DC, Concannon CG, Prehn JH.

Eur J Neurosci. 2011 Feb;33(3):401-8. doi: 10.1111/j.1460-9568.2010.07538.x. Epub 2010 Dec 31.

PMID:
21198986
15.

Activation of multidomain and BH3-only pro-apoptotic Bcl-2 family members in p53-defective cells.

Paquet C, Schmitt E, Beauchemin M, Bertrand R.

Apoptosis. 2004 Nov;9(6):815-31.

PMID:
15505424
16.

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

Tan TT, Degenhardt K, Nelson DA, Beaudoin B, Nieves-Neira W, Bouillet P, Villunger A, Adams JM, White E.

Cancer Cell. 2005 Mar;7(3):227-38.

17.

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis.

Marani M, Tenev T, Hancock D, Downward J, Lemoine NR.

Mol Cell Biol. 2002 Jun;22(11):3577-89.

18.

Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.

Han J, Goldstein LA, Gastman BR, Rabinovitz A, Rabinowich H.

J Biol Chem. 2005 Apr 22;280(16):16383-92. Epub 2005 Feb 15.

19.
20.

ARF tumor suppressor induces mitochondria-dependent apoptosis by modulation of mitochondrial Bcl-2 family proteins.

Nakazawa Y, Kamijo T, Koike K, Noda T.

J Biol Chem. 2003 Jul 25;278(30):27888-95. Epub 2003 May 9.

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