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Items: 1 to 20 of 107

1.

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.

Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLeod RA, Drexler HG, Look AT, Gilliland DG, Michaux L, Vandenberghe P, Wlodarska I, Marynen P, Hagemeijer A.

Nat Genet. 2004 Oct;36(10):1084-9. Epub 2004 Sep 12.

PMID:
15361874
2.

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

De Keersmaecker K, Graux C, Odero MD, Mentens N, Somers R, Maertens J, Wlodarska I, Vandenberghe P, Hagemeijer A, Marynen P, Cools J.

Blood. 2005 Jun 15;105(12):4849-52. Epub 2005 Feb 15.

3.

ABL1 fusions in T-cell acute lymphoblastic leukemia.

De Keersmaecker K.

Verh K Acad Geneeskd Belg. 2008;70(4):245-55. Review.

PMID:
19166098
4.

Fusion of NUP214 to ABL1 on amplified episomes in T-ALL--implications for treatment.

Stergianou K, Fox C, Russell NH.

Leukemia. 2005 Sep;19(9):1680-1. No abstract available.

PMID:
16015385
5.

NUP214-ABL1 in adult T-ALL: the GMALL study group experience.

Burmeister T, Gökbuget N, Reinhardt R, Rieder H, Hoelzer D, Schwartz S.

Blood. 2006 Nov 15;108(10):3556-9. Epub 2006 Jul 27.

6.

Characterization of ABL1 expression in adult T-cell acute lymphoblastic leukemia by oligonucleotide array analysis.

Chiaretti S, Tavolaro S, Ghia EM, Ariola C, Matteucci C, Elia L, Maggio R, Messina M, Ricciardi MR, Vitale A, Ritz J, Mecucci C, Guarini A, Foà R.

Haematologica. 2007 May;92(5):619-26.

7.

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, Vandenberghe P, Odero MD, Marynen P, Cools J.

Haematologica. 2008 Apr;93(4):533-42. doi: 10.3324/haematol.11894. Epub 2008 Mar 5.

8.

Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies.

Quintás-Cardama A, Tong W, Manshouri T, Vega F, Lennon PA, Cools J, Gilliland DG, Lee F, Cortes J, Kantarjian H, Garcia-Manero G.

Leukemia. 2008 Jun;22(6):1117-24. doi: 10.1038/leu.2008.80. Epub 2008 Apr 10.

PMID:
18401417
9.

ABL1 rearrangements in T-cell acute lymphoblastic leukemia.

Hagemeijer A, Graux C.

Genes Chromosomes Cancer. 2010 Apr;49(4):299-308. doi: 10.1002/gcc.20743. Review.

PMID:
20073070
10.

Establishment and cytogenetic characterization of a human acute lymphoblastic leukemia cell line (ALL-VG) with ETV6/ABL1 rearrangement.

Baeumler J, Szuhai K, Falkenburg JH, van Schie ML, Ottmann OG, Nijmeijer BA.

Cancer Genet Cytogenet. 2008 Aug;185(1):37-42. doi: 10.1016/j.cancergencyto.2008.05.001.

PMID:
18656692
11.

ABL1 amplification in T-cell acute lymphoblastic leukemia.

Bernasconi P, Calatroni S, Giardini I, Inzoli A, Castagnola C, Cavigliano PM, Rocca B, Boni M, Quarna J, Zappatore R, Caresana M, Bianchessi C, Pallavicini EB, Lazzarino M.

Cancer Genet Cytogenet. 2005 Oct 15;162(2):146-50.

PMID:
16213363
12.

Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia.

Graux C, Stevens-Kroef M, Lafage M, Dastugue N, Harrison CJ, Mugneret F, Bahloula K, Struski S, Grégoire MJ, Nadal N, Lippert E, Taviaux S, Simons A, Kuiper RP, Moorman AV, Barber K, Bosly A, Michaux L, Vandenberghe P, Lahortiga I, De Keersmaecker K, Wlodarska I, Cools J, Hagemeijer A, Poirel HA; Groupe Francophone de Cytogénétique Hématologique.; Belgian Cytogenetic Group for Hematology and Oncology..

Leukemia. 2009 Jan;23(1):125-33. doi: 10.1038/leu.2008.278. Epub 2008 Oct 16.

PMID:
18923437
13.

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

De Keersmaecker K, Rocnik JL, Bernad R, Lee BH, Leeman D, Gielen O, Verachtert H, Folens C, Munck S, Marynen P, Fornerod M, Gilliland DG, Cools J.

Mol Cell. 2008 Jul 11;31(1):134-42. doi: 10.1016/j.molcel.2008.05.005.

14.

SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines.

Quentmeier H, Schneider B, Röhrs S, Romani J, Zaborski M, Macleod RA, Drexler HG.

J Hematol Oncol. 2009 Jan 23;2:3. doi: 10.1186/1756-8722-2-3.

15.

Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia.

Van Limbergen H, Beverloo HB, van Drunen E, Janssens A, Hählen K, Poppe B, Van Roy N, Marynen P, De Paepe A, Slater R, Speleman F.

Genes Chromosomes Cancer. 2001 Mar;30(3):274-82.

PMID:
11170285
16.

Clonal eosinophils are a morphologic hallmark of ETV6/ABL1 positive acute myeloid leukemia.

La Starza R, Trubia M, Testoni N, Ottaviani E, Belloni E, Crescenzi B, Martelli M, Flandrin G, Pelicci PG, Mecucci C.

Haematologica. 2002 Aug;87(8):789-94.

17.

Impact of genotype on survival of children with T-cell acute lymphoblastic leukemia treated according to the French protocol FRALLE-93: the effect of TLX3/HOX11L2 gene expression on outcome.

Ballerini P, Landman-Parker J, Cayuela JM, Asnafi V, Labopin M, Gandemer V, Perel Y, Michel G, Leblanc T, Schmitt C, Fasola S, Hagemejier A, Sigaux F, Auclerc MF, Douay L, Leverger G, Baruchel A.

Haematologica. 2008 Nov;93(11):1658-65. doi: 10.3324/haematol.13291. Epub 2008 Oct 2.

18.

Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases.

De Keersmaecker K, Versele M, Cools J, Superti-Furga G, Hantschel O.

Leukemia. 2008 Dec;22(12):2208-16. doi: 10.1038/leu.2008.242. Epub 2008 Sep 11.

PMID:
18784740
19.

RCSD1-ABL1-positive B lymphoblastic leukemia is sensitive to dexamethasone and tyrosine kinase inhibitors and rapidly evolves clonally by chromosomal translocations.

Inokuchi K, Wakita S, Hirakawa T, Tamai H, Yokose N, Yamaguchi H, Dan K.

Int J Hematol. 2011 Sep;94(3):255-60. doi: 10.1007/s12185-011-0910-z. Epub 2011 Aug 24.

PMID:
21863287
20.

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.

De Keersmaecker K, Porcu M, Cox L, Girardi T, Vandepoel R, de Beeck JO, Gielen O, Mentens N, Bennett KL, Hantschel O.

Haematologica. 2014 Jan;99(1):85-93. doi: 10.3324/haematol.2013.088674. Epub 2013 Jul 19.

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