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Items: 1 to 20 of 119


Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors.

Salnikow K, An WG, Melillo G, Blagosklonny MV, Costa M.

Carcinogenesis. 1999 Sep;20(9):1819-23.


Regulation of hypoxia-inducible genes by ETS1 transcription factor.

Salnikow K, Aprelikova O, Ivanov S, Tackett S, Kaczmarek M, Karaczyn A, Yee H, Kasprzak KS, Niederhuber J.

Carcinogenesis. 2008 Aug;29(8):1493-9. doi: 10.1093/carcin/bgn088. Epub 2008 Apr 1.


HIF-1α up-regulates NDRG1 expression through binding to NDRG1 promoter, leading to proliferation of lung cancer A549 cells.

Wang Q, Li LH, Gao GD, Wang G, Qu L, Li JG, Wang CM.

Mol Biol Rep. 2013 May;40(5):3723-9. doi: 10.1007/s11033-012-2448-4. Epub 2013 Mar 25.


The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.

Salnikow K, Davidson T, Zhang Q, Chen LC, Su W, Costa M.

Cancer Res. 2003 Jul 1;63(13):3524-30.


L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.

Chung LC, Tsui KH, Feng TH, Lee SL, Chang PL, Juang HH.

Am J Physiol Cell Physiol. 2012 Feb 15;302(4):C676-85. doi: 10.1152/ajpcell.00180.2011. Epub 2011 Nov 23.


Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo.

Said HM, Stein S, Hagemann C, Polat B, Staab A, Anacker J, Schoemig B, Theobald M, Flentje M, Vordermark D.

Oncol Rep. 2009 Jan;21(1):237-46.


Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.

Salnikow K, Costa M, Figg WD, Blagosklonny MV.

Cancer Res. 2000 Oct 15;60(20):5630-4.


Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.

Karaczyn A, Ivanov S, Reynolds M, Zhitkovich A, Kasprzak KS, Salnikow K.

J Cell Biochem. 2006 Apr 1;97(5):1025-35.


AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells.

Lee M, Hwang JT, Lee HJ, Jung SN, Kang I, Chi SG, Kim SS, Ha J.

J Biol Chem. 2003 Oct 10;278(41):39653-61. Epub 2003 Aug 4.


Rapid detection of the hypoxia-regulated CA-IX and NDRG1 gene expression in different glioblastoma cells in vitro.

Said HM, Polat B, Staab A, Hagemann C, Stein S, Flentje M, Theobald M, Katzer A, Vordermark D.

Oncol Rep. 2008 Aug;20(2):413-9.


DEC2 expression is positively correlated with HIF-1 activation and the invasiveness of human osteosarcomas.

Hu T, He N, Yang Y, Yin C, Sang N, Yang Q.

J Exp Clin Cancer Res. 2015 Feb 28;34:22. doi: 10.1186/s13046-015-0135-8.


Carcinogenic nickel induces genes involved with hypoxic stress.

Salnikow K, Blagosklonny MV, Ryan H, Johnson R, Costa M.

Cancer Res. 2000 Jan 1;60(1):38-41.


The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia.

Salnikow K, Kluz T, Costa M, Piquemal D, Demidenko ZN, Xie K, Blagosklonny MV.

Mol Cell Biol. 2002 Mar;22(6):1734-41.


Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.


Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

Greijer AE, van der Groep P, Kemming D, Shvarts A, Semenza GL, Meijer GA, van de Wiel MA, Belien JA, van Diest PJ, van der Wall E.

J Pathol. 2005 Jul;206(3):291-304.


Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.

Huang LE, Ho V, Arany Z, Krainc D, Galson D, Tendler D, Livingston DM, Bunn HF.

Kidney Int. 1997 Feb;51(2):548-52. Review.


The HIF pathway: implications for patterns of gene expression in cancer.

Wykoff CC, Pugh CW, Harris AL, Maxwell PH, Ratcliffe PJ.

Novartis Found Symp. 2001;240:212-25; discussion 225-31. Review.


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