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Items: 1 to 20 of 107

1.

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

Jeon MS, Atfield A, Venuprasad K, Krawczyk C, Sarao R, Elly C, Yang C, Arya S, Bachmaier K, Su L, Bouchard D, Jones R, Gronski M, Ohashi P, Wada T, Bloom D, Fathman CG, Liu YC, Penninger JM.

Immunity. 2004 Aug;21(2):167-77.

2.

Regulation of peripheral T cell tolerance by the E3 ubiquitin ligase Cbl-b.

Loeser S, Penninger JM.

Semin Immunol. 2007 Jun;19(3):206-14. Epub 2007 Mar 27. Review.

PMID:
17391982
3.

Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.

Paolino M, Thien CB, Gruber T, Hinterleitner R, Baier G, Langdon WY, Penninger JM.

J Immunol. 2011 Feb 15;186(4):2138-47. doi: 10.4049/jimmunol.1003390. Epub 2011 Jan 19.

4.

The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cells.

St Rose MC, Qui HZ, Bandyopadhyay S, Mihalyo MA, Hagymasi AT, Clark RB, Adler AJ.

J Immunol. 2009 Oct 15;183(8):4975-83. doi: 10.4049/jimmunol.0901243.

5.

Activation of T cells: releasing the brakes by proteolytic elimination of Cbl-b.

Schmitz ML.

Sci Signal. 2009 Jun 23;2(76):pe38. doi: 10.1126/scisignal.276pe38. Review.

PMID:
19549983
6.

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.

Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, Penninger JM.

Nature. 2000 Jan 13;403(6766):211-6.

PMID:
10646608
7.

E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.

Guo H, Qiao G, Ying H, Li Z, Zhao Y, Liang Y, Yang L, Lipkowitz S, Penninger JM, Langdon WY, Zhang J.

Cell Rep. 2012 May 31;1(5):472-82.

8.

Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b.

Krawczyk CM, Jones RG, Atfield A, Bachmaier K, Arya S, Odermatt B, Ohashi PS, Penninger JM.

J Immunol. 2005 Feb 1;174(3):1472-8.

9.

E3 ubiquitin ligases as T cell anergy factors.

Mueller DL.

Nat Immunol. 2004 Sep;5(9):883-90. Review.

PMID:
15334084
10.

Egr-2 and Egr-3 are negative regulators of T cell activation.

Safford M, Collins S, Lutz MA, Allen A, Huang CT, Kowalski J, Blackford A, Horton MR, Drake C, Schwartz RH, Powell JD.

Nat Immunol. 2005 May;6(5):472-80. Epub 2005 Apr 17. Erratum in: Nat Immunol. 2005 Jul;6(7):737.

PMID:
15834410
11.

T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.

Qiao G, Zhao Y, Li Z, Tang PQ, Langdon WY, Yang T, Zhang J.

J Immunol. 2013 Jul 15;191(2):632-9. doi: 10.4049/jimmunol.1202068. Epub 2013 Jun 7.

12.

The anergy induction of M3 muscarinic acetylcholine receptor-reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome.

Asashima H, Tsuboi H, Takahashi H, Hirota T, Iizuka M, Kondo Y, Matsui M, Matsumoto I, Sumida T.

Arthritis Rheumatol. 2015 May;67(8):2213-25. doi: 10.1002/art.39163.

13.

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.

Heissmeyer V, Macián F, Im SH, Varma R, Feske S, Venuprasad K, Gu H, Liu YC, Dustin ML, Rao A.

Nat Immunol. 2004 Mar;5(3):255-65. Epub 2004 Feb 15.

PMID:
14973438
14.

Visualizing the role of Cbl-b in control of islet-reactive CD4 T cells and susceptibility to type 1 diabetes.

Hoyne GF, Flening E, Yabas M, Teh C, Altin JA, Randall K, Thien CB, Langdon WY, Goodnow CC.

J Immunol. 2011 Feb 15;186(4):2024-32. doi: 10.4049/jimmunol.1002296. Epub 2011 Jan 19.

15.

Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.

Kitaura Y, Jang IK, Wang Y, Han YC, Inazu T, Cadera EJ, Schlissel M, Hardy RR, Gu H.

Immunity. 2007 May;26(5):567-78. Epub 2007 May 10.

16.
17.

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.

Gruber T, Hermann-Kleiter N, Hinterleitner R, Fresser F, Schneider R, Gastl G, Penninger JM, Baier G.

Sci Signal. 2009 Jun 23;2(76):ra30. doi: 10.1126/scisignal.2000046.

18.

Cbl-b regulates the CD28 dependence of T-cell activation.

Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, Jang IK, Gutkind JS, Shevach E, Gu H.

Nature. 2000 Jan 13;403(6766):216-20.

PMID:
10646609
19.

Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b.

Qu X, Sada K, Kyo S, Maeno K, Miah SM, Yamamura H.

Blood. 2004 Mar 1;103(5):1779-86. Epub 2003 Nov 6.

20.

E3 Ubiquitin Ligase Cbl-b Regulates Thymic-Derived CD4+CD25+ Regulatory T Cell Development by Targeting Foxp3 for Ubiquitination.

Zhao Y, Guo H, Qiao G, Zucker M, Langdon WY, Zhang J.

J Immunol. 2015 Feb 15;194(4):1639-45. doi: 10.4049/jimmunol.1402434. Epub 2015 Jan 5.

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