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Items: 1 to 20 of 147


Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.

Shu M, Taddeo B, Roizman B.

J Virol. 2015 May;89(10):5643-50. doi: 10.1128/JVI.00091-15. Epub 2015 Mar 11.


The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.

Esclatine A, Taddeo B, Evans L, Roizman B.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3603-8. Epub 2004 Mar 1.


Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells.

Taddeo B, Esclatine A, Roizman B.

Biochem Soc Trans. 2004 Nov;32(Pt 5):697-701. Review.


Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.

Taddeo B, Zhang W, Roizman B.

J Virol. 2010 Oct;84(19):10182-90. doi: 10.1128/JVI.00975-10. Epub 2010 Jul 14.


The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.

Taddeo B, Zhang W, Roizman B.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2827-32. Epub 2006 Feb 13.


Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.

Shu M, Taddeo B, Zhang W, Roizman B.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1669-75. doi: 10.1073/pnas.1305475110. Epub 2013 Apr 15.


Nuclear-cytoplasmic compartmentalization of the herpes simplex virus 1 infected cell transcriptome is co-ordinated by the viral endoribonuclease vhs and cofactors to facilitate the translation of late proteins.

Pheasant K, Möller-Levet CS, Jones J, Depledge D, Breuer J, Elliott G.

PLoS Pathog. 2018 Nov 26;14(11):e1007331. doi: 10.1371/journal.ppat.1007331. eCollection 2018 Nov.


Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.

Burgess HM, Mohr I.

J Virol. 2018 Jul 17;92(15). pii: e00829-18. doi: 10.1128/JVI.00829-18. Print 2018 Aug 1.


The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs.

Esclatine A, Taddeo B, Roizman B.

Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18165-70. Epub 2004 Dec 13.


The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes.

Taddeo B, Zhang W, Roizman B.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12139-44. doi: 10.1073/pnas.0905828106. Epub 2009 Jul 7.


Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.

Hsu WL, Saffran HA, Smiley JR.

J Virol. 2005 Apr;79(7):4090-8.


The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM.

J Virol. 2011 Dec;85(23):12662-72. doi: 10.1128/JVI.05557-11. Epub 2011 Sep 21.


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