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Items: 1 to 20 of 122

1.

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, Kowalewski T, Holtzman DM.

J Biol Chem. 2004 Sep 24;279(39):40987-93. Epub 2004 Jul 21.

2.

Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain.

Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL.

J Biol Chem. 2004 Sep 24;279(39):41197-207. Epub 2004 Jul 21.

3.

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice.

DeMattos RB, Brendza RP, Heuser JE, Kierson M, Cirrito JR, Fryer J, Sullivan PM, Fagan AM, Han X, Holtzman DM.

Neurochem Int. 2001 Nov-Dec;39(5-6):415-25.

PMID:
11578777
4.

Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes.

Maric J, Kiss RS, Franklin V, Marcel YL.

J Biol Chem. 2005 Dec 2;280(48):39942-9. Epub 2005 Oct 4.

5.

LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.

Hirsch-Reinshagen V, Donkin J, Stukas S, Chan J, Wilkinson A, Fan J, Parks JS, Kuivenhoven JA, Lütjohann D, Pritchard H, Wellington CL.

J Lipid Res. 2009 May;50(5):885-93. doi: 10.1194/jlr.M800584-JLR200. Epub 2008 Dec 8.

6.

Astrocyte׳s endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA1.

Ito J, Nagayasu Y, Miura Y, Yokoyama S, Michikawa M.

Brain Res. 2014 Jun 27;1570:1-12. doi: 10.1016/j.brainres.2014.04.037. Epub 2014 May 9.

PMID:
24814386
7.

The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1.

Stukas S, May S, Wilkinson A, Chan J, Donkin J, Wellington CL.

Biochim Biophys Acta. 2012 Mar;1821(3):536-46. doi: 10.1016/j.bbalip.2011.08.014. Epub 2011 Aug 26.

PMID:
21889608
8.

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.

Koldamova R, Staufenbiel M, Lefterov I.

J Biol Chem. 2005 Dec 30;280(52):43224-35. Epub 2005 Oct 5.

9.

The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL.

J Biol Chem. 2005 Dec 30;280(52):43243-56. Epub 2005 Oct 5.

10.

ApoA-I lipidation in primary mouse hepatocytes. Separate controls for phospholipid and cholesterol transfers.

Zheng H, Kiss RS, Franklin V, Wang MD, Haidar B, Marcel YL.

J Biol Chem. 2005 Jun 3;280(22):21612-21. Epub 2005 Mar 29.

11.

Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes.

Sato K, Malchinkhuu E, Horiuchi Y, Mogi C, Tomura H, Tosaka M, Yoshimoto Y, Kuwabara A, Okajima F.

J Neurochem. 2007 Dec;103(6):2610-9. doi: 10.1111/j.1471-4159.2007.04958.x.

12.

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.

Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM.

J Biol Chem. 2005 Dec 30;280(52):43236-42. Epub 2005 Oct 5.

13.

Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.

Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM.

J Clin Invest. 2008 Feb;118(2):671-82. doi: 10.1172/JCI33622.

14.

Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia.

Karten B, Campenot RB, Vance DE, Vance JE.

J Biol Chem. 2006 Feb 17;281(7):4049-57. Epub 2005 Dec 13.

15.

A novel function of apolipoprotein E: upregulation of ATP-binding cassette transporter A1 expression.

Zhao Y, Chen X, Yang H, Zhou L, Okoro EU, Guo Z.

PLoS One. 2011;6(7):e21453. doi: 10.1371/journal.pone.0021453. Epub 2011 Jul 11.

16.

Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux.

Kockx M, Rye KA, Gaus K, Quinn CM, Wright J, Sloane T, Sviridov D, Fu Y, Sullivan D, Burnett JR, Rust S, Assmann G, Anantharamaiah GM, Palgunachari MN, Katz SL, Phillips MC, Dean RT, Jessup W, Kritharides L.

J Biol Chem. 2004 Jun 18;279(25):25966-77. Epub 2004 Apr 1.

17.

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.

Joyce CW, Amar MJ, Lambert G, Vaisman BL, Paigen B, Najib-Fruchart J, Hoyt RF Jr, Neufeld ED, Remaley AT, Fredrickson DS, Brewer HB Jr, Santamarina-Fojo S.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):407-12. Epub 2001 Dec 18.

18.

Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.

Fitz NF, Tapias V, Cronican AA, Castranio EL, Saleem M, Carter AY, Lefterova M, Lefterov I, Koldamova R.

Brain. 2015 Dec;138(Pt 12):3699-715. doi: 10.1093/brain/awv293. Epub 2015 Oct 28.

19.

Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.

Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G.

J Biol Chem. 2014 Apr 18;289(16):11282-92. doi: 10.1074/jbc.M113.526095. Epub 2014 Mar 5.

20.

Molecular interactions between apoE and ABCA1: impact on apoE lipidation.

Krimbou L, Denis M, Haidar B, Carrier M, Marcil M, Genest J Jr.

J Lipid Res. 2004 May;45(5):839-48. Epub 2004 Feb 1.

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