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Items: 1 to 20 of 124


The RING-H2-finger protein APC11 as a target of hydrogen peroxide.

Chang TS, Jeong W, Lee DY, Cho CS, Rhee SG.

Free Radic Biol Med. 2004 Aug 15;37(4):521-30.


APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

Tang Z, Li B, Bharadwaj R, Zhu H, Ozkan E, Hakala K, Deisenhofer J, Yu H.

Mol Biol Cell. 2001 Dec;12(12):3839-51.


The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.

Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8973-8.


Human T-lymphotropic virus type 1 oncoprotein tax promotes unscheduled degradation of Pds1p/securin and Clb2p/cyclin B1 and causes chromosomal instability.

Liu B, Liang MH, Kuo YL, Liao W, Boros I, Kleinberger T, Blancato J, Giam CZ.

Mol Cell Biol. 2003 Aug;23(15):5269-81.


The APC11 RING-H2 finger mediates E2-dependent ubiquitination.

Leverson JD, Joazeiro CA, Page AM, Huang Hk, Hieter P, Hunter T.

Mol Biol Cell. 2000 Jul;11(7):2315-25.


Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex.

Kraft C, Gmachl M, Peters JM.

Methods. 2006 Jan;38(1):39-51. Review.


RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.

Brown NG, VanderLinden R, Watson ER, Qiao R, Grace CR, Yamaguchi M, Weissmann F, Frye JJ, Dube P, Ei Cho S, Actis ML, Rodrigues P, Fujii N, Peters JM, Stark H, Schulman BA.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5272-9. doi: 10.1073/pnas.1504161112. Epub 2015 Mar 30.


Cell cycle deregulation by a poxvirus partial mimic of anaphase-promoting complex subunit 11.

Mo M, Fleming SB, Mercer AA.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19527-32. doi: 10.1073/pnas.0905893106. Epub 2009 Nov 3.


Degradation of cyclin B is required for the onset of anaphase in Mammalian cells.

Chang DC, Xu N, Luo KQ.

J Biol Chem. 2003 Sep 26;278(39):37865-73. Epub 2003 Jul 14.


APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1.

Dimova NV, Hathaway NA, Lee BH, Kirkpatrick DS, Berkowitz ML, Gygi SP, Finley D, King RW.

Nat Cell Biol. 2012 Jan 29;14(2):168-76. doi: 10.1038/ncb2425.


Atomic structure of the APC/C and its mechanism of protein ubiquitination.

Chang L, Zhang Z, Yang J, McLaughlin SH, Barford D.

Nature. 2015 Jun 25;522(7557):450-454. doi: 10.1038/nature14471. Epub 2015 Jun 15.


UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex.

Wu T, Merbl Y, Huo Y, Gallop JL, Tzur A, Kirschner MW.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1355-60. doi: 10.1073/pnas.0912802107. Epub 2010 Jan 6.


HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule.

Liu B, Hong S, Tang Z, Yu H, Giam CZ.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):63-8. Epub 2004 Dec 27.


Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.

Brown NG, Watson ER, Weissmann F, Jarvis MA, VanderLinden R, Grace CR, Frye JJ, Qiao R, Dube P, Petzold G, Cho SE, Alsharif O, Bao J, Davidson IF, Zheng JJ, Nourse A, Kurinov I, Peters JM, Stark H, Schulman BA.

Mol Cell. 2014 Oct 23;56(2):246-60. doi: 10.1016/j.molcel.2014.09.009. Epub 2014 Oct 9.


The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

Carroll CW, Morgan DO.

Nat Cell Biol. 2002 Nov;4(11):880-7.


Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase.

Casaletto JB, Nutt LK, Wu Q, Moore JD, Etkin LD, Jackson PK, Hunt T, Kornbluth S.

J Cell Biol. 2005 Apr 11;169(1):61-71.


The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation.

Máthé E, Kraft C, Giet R, Deák P, Peters JM, Glover DM.

Curr Biol. 2004 Oct 5;14(19):1723-33.


lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2.

Nagy O, Pál M, Udvardy A, Shirras CA, Boros I, Shirras AD, Deák P.

Cell Div. 2012 Mar 14;7(1):9. doi: 10.1186/1747-1028-7-9.

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