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Items: 1 to 20 of 107

1.

Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.

Melnychuk RM, Streblow DN, Smith PP, Hirsch AJ, Pancheva D, Nelson JA.

J Virol. 2004 Aug;78(15):8382-91.

2.

Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility.

Vomaske J, Melnychuk RM, Smith PP, Powell J, Hall L, DeFilippis V, Früh K, Smit M, Schlaepfer DD, Nelson JA, Streblow DN.

PLoS Pathog. 2009 Feb;5(2):e1000304. doi: 10.1371/journal.ppat.1000304. Epub 2009 Feb 20.

3.

Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.

Joshi S, Wels C, Beham-Schmid C, Fukunaga-Kalabis M, Holmen SL, Otte M, Herlyn M, Waldhoer M, Schaider H.

Int J Cancer. 2015 Sep 15;137(6):1503-8. doi: 10.1002/ijc.29506. Epub 2015 Mar 16.

4.

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration.

Streblow DN, Soderberg-Naucler C, Vieira J, Smith P, Wakabayashi E, Ruchti F, Mattison K, Altschuler Y, Nelson JA.

Cell. 1999 Nov 24;99(5):511-20.

5.

Mouse cytomegalovirus M33 is necessary and sufficient in virus-induced vascular smooth muscle cell migration.

Melnychuk RM, Smith P, Kreklywich CN, Ruchti F, Vomaske J, Hall L, Loh L, Nelson JA, Orloff SL, Streblow DN.

J Virol. 2005 Aug;79(16):10788-95.

6.

Human cytomegalovirus chemokine receptor US28-induced smooth muscle cell migration is mediated by focal adhesion kinase and Src.

Streblow DN, Vomaske J, Smith P, Melnychuk R, Hall L, Pancheva D, Smit M, Casarosa P, Schlaepfer DD, Nelson JA.

J Biol Chem. 2003 Dec 12;278(50):50456-65. Epub 2003 Sep 22.

7.

Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.

Casarosa P, Bakker RA, Verzijl D, Navis M, Timmerman H, Leurs R, Smit MJ.

J Biol Chem. 2001 Jan 12;276(2):1133-7.

8.

The HCMV chemokine receptor US28 is a potential target in vascular disease.

Streblow DN, Orloff SL, Nelson JA.

Curr Drug Targets Infect Disord. 2001 Aug;1(2):151-8. Review.

PMID:
12455411
9.

Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype.

Soroceanu L, Matlaf L, Bezrookove V, Harkins L, Martinez R, Greene M, Soteropoulos P, Cobbs CS.

Cancer Res. 2011 Nov 1;71(21):6643-53. doi: 10.1158/0008-5472.CAN-11-0744. Epub 2011 Sep 7.

10.

US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells.

Miller WE, Zagorski WA, Brenneman JD, Avery D, Miller JL, O'Connor CM.

PLoS One. 2012;7(11):e50524. doi: 10.1371/journal.pone.0050524. Epub 2012 Nov 29.

11.

Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface.

Hjortø GM, Kiilerich-Pedersen K, Selmeczi D, Kledal TN, Larsen NB.

J Gen Virol. 2013 May;94(Pt 5):1111-20. doi: 10.1099/vir.0.047290-0. Epub 2013 Jan 9.

PMID:
23303826
12.

Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infection.

Billstrom MA, Johnson GL, Avdi NJ, Worthen GS.

J Virol. 1998 Jul;72(7):5535-44.

13.

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

Vogt S, Grosse R, Schultz G, Offermanns S.

J Biol Chem. 2003 Aug 1;278(31):28743-9. Epub 2003 May 27.

14.

Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.

Vomaske J, Nelson JA, Streblow DN.

Infect Disord Drug Targets. 2009 Nov;9(5):548-56. Review.

15.

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.

Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW.

J Biol Chem. 2003 May 23;278(21):19473-82. Epub 2003 Mar 18.

16.

Gα12/13 signaling promotes cervical cancer invasion through the RhoA/ROCK-JNK signaling axis.

Yuan B, Cui J, Wang W, Deng K.

Biochem Biophys Res Commun. 2016 May 13;473(4):1240-1246. doi: 10.1016/j.bbrc.2016.04.048. Epub 2016 Apr 12.

PMID:
27084452
17.

Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.

Gohla A, Schultz G, Offermanns S.

Circ Res. 2000 Aug 4;87(3):221-7.

PMID:
10926873
18.

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor.

Casarosa P, Menge WM, Minisini R, Otto C, van Heteren J, Jongejan A, Timmerman H, Moepps B, Kirchhoff F, Mertens T, Smit MJ, Leurs R.

J Biol Chem. 2003 Feb 14;278(7):5172-8. Epub 2002 Nov 26.

19.

US28 actions in HCMV infection: lessons from a versatile hijacker.

Boomker JM, van Luyn MJ, The TH, de Leij LF, Harmsen MC.

Rev Med Virol. 2005 Jul-Aug;15(4):269-82. Review.

PMID:
15861487
20.

12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.

Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr.

Br J Pharmacol. 2017 Dec;174(23):4383-4395. doi: 10.1111/bph.14040. Epub 2017 Nov 12.

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