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Items: 1 to 20 of 198

1.

Trypanocidal activity of bergenin, the major constituent of Flueggea virosa, on Trypanosoma brucei.

Nyasse B, Nono J, Sonke B, Denier C, Fontaine C.

Pharmazie. 2004 Jun;59(6):492-4.

PMID:
15248469
2.

Modified berberine and protoberberines from Enantia chlorantha as potential inhibitors of Trypanosoma brucei.

Nyasse B, Nkwengoua E, Sondengam B, Denier C, Willson M.

Pharmazie. 2002 Jun;57(6):358-61.

PMID:
12116870
3.

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

Bressi JC, Choe J, Hough MT, Buckner FS, Van Voorhis WC, Verlinde CL, Hol WG, Gelb MH.

J Med Chem. 2000 Nov 2;43(22):4135-50.

PMID:
11063610
4.

Uapaca genus (Euphorbiaceae), a good source of betulinic acid.

Nyasse B, Nono JJ, Nganso Y, Ngantchou I, Schneider B.

Fitoterapia. 2009 Jan;80(1):32-4. doi: 10.1016/j.fitote.2008.09.005. Epub 2008 Sep 30.

PMID:
18926889
5.

Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): their effects on three selected glycolytic enzymes of Trypanosoma brucei.

Ngantchou I, Nyasse B, Denier C, Blonski C, Hannaert V, Schneider B.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3495-8. doi: 10.1016/j.bmcl.2010.04.145. Epub 2010 May 6.

PMID:
20529682
6.

Inhibition of both Trypanosoma brucei bloodstream form and related glycolytic enzymes by a new kolavic acid derivative isolated from Entada abyssinica.

Nyasse B, Ngantchou I, Tchana EM, Sonké B, Denier C, Fontaine C.

Pharmazie. 2004 Nov;59(11):873-5.

PMID:
15587590
7.

Selective inhibition of Trypanosoma brucei GAPDH by 1,3-bisphospho-D-glyceric acid (1,3-diPG) analogues.

Ladame S, Bardet M, Périé J, Willson M.

Bioorg Med Chem. 2001 Mar;9(3):773-83.

PMID:
11310612
8.
9.

Bergenin is the antiarrhythmic principle of Fluggea virosa.

Pu HL, Huang X, Zhao JH, Hong A.

Planta Med. 2002 Apr;68(4):372-4.

PMID:
11988869
10.

Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase.

Bero J, Beaufay C, Hannaert V, Hérent MF, Michels PA, Quetin-Leclercq J.

Phytomedicine. 2013 Feb 15;20(3-4):270-4. doi: 10.1016/j.phymed.2012.10.010. Epub 2013 Jan 11.

PMID:
23312849
11.

In Silico Identification and in Vitro Activity of Novel Natural Inhibitors of Trypanosoma brucei Glyceraldehyde-3-phosphate-dehydrogenase.

Herrmann FC, Lenz M, Jose J, Kaiser M, Brun R, Schmidt TJ.

Molecules. 2015 Sep 3;20(9):16154-69. doi: 10.3390/molecules200916154.

12.

Inhibition of the glycolytic enzymes in the trypanosome: an approach in the development of new leads in the therapy of parasitic diseases.

Perie J, Riviere-Alric I, Blonski C, Gefflaut T, Lauth de Viguerie N, Trinquier M, Willson M, Opperdoes FR, Callens M.

Pharmacol Ther. 1993 Nov;60(2):347-65. Review.

PMID:
8022865
13.

[Rational concepts and the study of active molecules against various trypanosomiases].

Périé J, de Albuquerque C, Blonski C, Chauvière G, Gefflaut T, Page P, Trinquier M, Willson M.

Bull Soc Pathol Exot. 1994;87(5):353-61. French.

PMID:
7496200
14.
15.

Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.

Belluti F, Uliassi E, Veronesi G, Bergamini C, Kaiser M, Brun R, Viola A, Fato R, Michels PA, Krauth-Siegel RL, Cavalli A, Bolognesi ML.

ChemMedChem. 2014 Feb;9(2):371-82. doi: 10.1002/cmdc.201300399. Epub 2014 Jan 8.

PMID:
24403089
16.

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH.

Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4273-8.

17.

Bioactive compounds from Celaenodendron mexicanum.

Camacho MR, Mata R, Castaneda P, Kirby GC, Warhurst DC, Croft SL, Phillipson JD.

Planta Med. 2000 Jun;66(5):463-8.

PMID:
10909269
18.

In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense.

Merschjohann K, Sporer F, Steverding D, Wink M.

Planta Med. 2001 Oct;67(7):623-7.

PMID:
11582539
19.

The in vitro efficacy of reuterin on the culture and bloodstream forms of Trypanosoma brucei brucei.

Yunmbam MK, Roberts JF.

Comp Biochem Physiol C. 1992 Feb;101(2):235-8.

PMID:
1354096
20.

In vitro and in vivo evaluation of the antitrypanosomal activity of fractions of Holarrhena africana.

Nwodo NJ, Brun R, Osadebe PO.

J Ethnopharmacol. 2007 Sep 25;113(3):556-9. Epub 2007 Jul 22.

PMID:
17728085

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