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Items: 1 to 20 of 87


A novel anti-anti-activator mechanism regulates expression of the Pseudomonas aeruginosa type III secretion system.

Dasgupta N, Lykken GL, Wolfgang MC, Yahr TL.

Mol Microbiol. 2004 Jul;53(1):297-308.


ExsD inhibits expression of the Pseudomonas aeruginosa type III secretion system by disrupting ExsA self-association and DNA binding activity.

Brutinel ED, Vakulskas CA, Yahr TL.

J Bacteriol. 2010 Mar;192(6):1479-86. doi: 10.1128/JB.01457-09. Epub 2009 Dec 11.


Biochemical characterization of a regulatory cascade controlling transcription of the Pseudomonas aeruginosa type III secretion system.

Zheng Z, Chen G, Joshi S, Brutinel ED, Yahr TL, Chen L.

J Biol Chem. 2007 Mar 2;282(9):6136-42. Epub 2006 Dec 29.


A secreted regulatory protein couples transcription to the secretory activity of the Pseudomonas aeruginosa type III secretion system.

Urbanowski ML, Lykken GL, Yahr TL.

Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9930-5. Epub 2005 Jun 28.


ExsD is a negative regulator of the Pseudomonas aeruginosa type III secretion regulon.

McCaw ML, Lykken GL, Singh PK, Yahr TL.

Mol Microbiol. 2002 Nov;46(4):1123-33.


Self-trimerization of ExsD limits inhibition of the Pseudomonas aeruginosa transcriptional activator ExsA in vitro.

Bernhards RC, Marsden AE, Esher SK, Yahr TL, Schubot FD.

FEBS J. 2013 Feb;280(4):1084-94. doi: 10.1111/febs.12103. Epub 2013 Jan 24.


Anti-activator ExsD forms a 1:1 complex with ExsA to inhibit transcription of type III secretion operons.

Thibault J, Faudry E, Ebel C, Attree I, Elsen S.

J Biol Chem. 2009 Jun 5;284(23):15762-70. doi: 10.1074/jbc.M109.003533. Epub 2009 Apr 15.


Characterization of ExsC and ExsD self-association and heterocomplex formation.

Lykken GL, Chen G, Brutinel ED, Chen L, Yahr TL.

J Bacteriol. 2006 Oct;188(19):6832-40.


Functional domains of ExsA, the transcriptional activator of the Pseudomonas aeruginosa type III secretion system.

Brutinel ED, Vakulskas CA, Yahr TL.

J Bacteriol. 2009 Jun;191(12):3811-21. doi: 10.1128/JB.00002-09. Epub 2009 Apr 17.


Structural evidence suggests that antiactivator ExsD from Pseudomonas aeruginosa is a DNA binding protein.

Bernhards RC, Jing X, Vogelaar NJ, Robinson H, Schubot FD.

Protein Sci. 2009 Mar;18(3):503-13. doi: 10.1002/pro.48.


Type III secretion system 1 genes in Vibrio parahaemolyticus are positively regulated by ExsA and negatively regulated by ExsD.

Zhou X, Shah DH, Konkel ME, Call DR.

Mol Microbiol. 2008 Aug;69(3):747-64. doi: 10.1111/j.1365-2958.2008.06326.x. Epub 2008 Jun 28.


ExsA recruits RNA polymerase to an extended -10 promoter by contacting region 4.2 of sigma-70.

Vakulskas CA, Brutinel ED, Yahr TL.

J Bacteriol. 2010 Jul;192(14):3597-607. doi: 10.1128/JB.00129-10. Epub 2010 May 7.


Mechanism of transcriptional activation by Pseudomonas aeruginosa ExsA.

Vakulskas CA, Brady KM, Yahr TL.

J Bacteriol. 2009 Nov;191(21):6654-64. doi: 10.1128/JB.00902-09. Epub 2009 Aug 28.


The distal ExsA-binding site in Pseudomonas aeruginosa type III secretion system promoters is the primary determinant for promoter-specific properties.

Brutinel ED, King JM, Marsden AE, Yahr TL.

J Bacteriol. 2012 May;194(10):2564-72. doi: 10.1128/JB.00106-12. Epub 2012 Mar 9.


Structural Analysis of the Regulatory Domain of ExsA, a Key Transcriptional Regulator of the Type Three Secretion System in Pseudomonas aeruginosa.

Shrestha M, Xiao Y, Robinson H, Schubot FD.

PLoS One. 2015 Aug 28;10(8):e0136533. doi: 10.1371/journal.pone.0136533. eCollection 2015.


An in vivo inducible gene of Pseudomonas aeruginosa encodes an anti-ExsA to suppress the type III secretion system.

Ha UH, Kim J, Badrane H, Jia J, Baker HV, Wu D, Jin S.

Mol Microbiol. 2004 Oct;54(2):307-20.


Pseudomonas aeruginosa Magnesium Transporter MgtE Inhibits Type III Secretion System Gene Expression by Stimulating rsmYZ Transcription.

Chakravarty S, Melton CN, Bailin A, Yahr TL, Anderson GG.

J Bacteriol. 2017 Oct 31;199(23). pii: e00268-17. doi: 10.1128/JB.00268-17. Print 2017 Dec 1.

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