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Items: 1 to 20 of 117

1.

Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells.

Becker S, Simpson JC, Pepperkok R, Heinz S, Herder C, Grez M, Seifried E, Tonn T.

Thromb Haemost. 2004 Jul;92(1):23-35.

PMID:
15213841
2.

Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII.

Heinz S, Schüttrumpf J, Simpson JC, Pepperkok R, Nicolaes GA, Abriss D, Milanov P, Roth S, Seifried E, Tonn T.

Thromb Haemost. 2009 Nov;102(5):925-35. doi: 10.1160/TH08-12-0807.

PMID:
19888531
3.
4.

Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A.

Roth SD, Schüttrumpf J, Milanov P, Abriss D, Ungerer C, Quade-Lyssy P, Simpson JC, Pepperkok R, Seifried E, Tonn T.

PLoS One. 2012;7(9):e44505. doi: 10.1371/journal.pone.0044505. Epub 2012 Sep 4.

5.

Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII).

Zheng C, Page RC, Das V, Nix JC, Wigren E, Misra S, Zhang B.

J Biol Chem. 2013 Jul 12;288(28):20499-509. doi: 10.1074/jbc.M113.461434. Epub 2013 May 24.

6.

Enhanced biosynthesis of coagulation factor VIII through diminished engagement of the unfolded protein response.

Brown HC, Gangadharan B, Doering CB.

J Biol Chem. 2011 Jul 8;286(27):24451-7. doi: 10.1074/jbc.M111.238758. Epub 2011 May 23.

7.

Biosynthesis, assembly and secretion of coagulation factor VIII.

Kaufman RJ, Pipe SW, Tagliavacca L, Swaroop M, Moussalli M.

Blood Coagul Fibrinolysis. 1997 Dec;8 Suppl 2:S3-14. Review.

PMID:
9607108
8.
9.

Expression of factor VIII in recombinant and transgenic systems.

Soukharev S, Hammond D, Ananyeva NM, Anderson JA, Hauser CA, Pipe S, Saenko EL.

Blood Cells Mol Dis. 2002 Mar-Apr;28(2):234-48. Review.

PMID:
12064919
10.

Bioengineering of coagulation factor VIII for improved secretion.

Miao HZ, Sirachainan N, Palmer L, Kucab P, Cunningham MA, Kaufman RJ, Pipe SW.

Blood. 2004 May 1;103(9):3412-9. Epub 2004 Jan 15.

11.

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

Zhang B, Zheng C, Zhu M, Tao J, Vasievich MP, Baines A, Kim J, Schekman R, Kaufman RJ, Ginsburg D.

Blood. 2011 Sep 22;118(12):3384-91. doi: 10.1182/blood-2011-05-352815. Epub 2011 Jul 27.

12.
13.

Enhanced Proteolytic Processing of Recombinant Human Coagulation Factor VIII B-Domain Variants by Recombinant Furins.

Demasi MA, de S Molina E, Bowman-Colin C, Lojudice FH, Muras A, Sogayar MC.

Mol Biotechnol. 2016 Jun;58(6):404-14. doi: 10.1007/s12033-016-9939-9.

PMID:
27126696
14.

Mutagenesis of a potential immunoglobulin-binding protein-binding site enhances secretion of coagulation factor VIII.

Swaroop M, Moussalli M, Pipe SW, Kaufman RJ.

J Biol Chem. 1997 Sep 26;272(39):24121-4.

16.

A 110-amino acid region within the A1-domain of coagulation factor VIII inhibits secretion from mammalian cells.

Marquette KA, Pittman DD, Kaufman RJ.

J Biol Chem. 1995 Apr 28;270(17):10297-303.

17.

In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile.

Pahl S, Pavlova A, Driesen J, Müller J, Pötzsch B, Oldenburg J.

Haemophilia. 2013 May;19(3):392-8. doi: 10.1111/hae.12076. Epub 2012 Dec 18.

PMID:
23252674
18.

Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen.

Satoh M, Hirayoshi K, Yokota S, Hosokawa N, Nagata K.

J Cell Biol. 1996 Apr;133(2):469-83.

19.

Comparison of factor VIII transgenes bioengineered for improved expression in gene therapy of hemophilia A.

Dooriss KL, Denning G, Gangadharan B, Javazon EH, McCarty DA, Spencer HT, Doering CB.

Hum Gene Ther. 2009 May;20(5):465-78. doi: 10.1089/hum.2008.150.

20.

Cell surface staining of recombinant factor VIII is reduced in apoptosis resistant BHK-21 cells.

Ishaque A, Thrift J, Murphy JE, Konstantinov K.

J Biotechnol. 2008 Oct 10;137(1-4):20-7. doi: 10.1016/j.jbiotec.2008.07.1856. Epub 2008 Jul 25.

PMID:
18703095

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