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Items: 1 to 20 of 157

1.

Could a loss of alpha-synuclein function put dopaminergic neurons at risk?

Perez RG, Hastings TG.

J Neurochem. 2004 Jun;89(6):1318-24. Review.

2.

A Drosophila model of Parkinson's disease.

Feany MB, Bender WW.

Nature. 2000 Mar 23;404(6776):394-8.

PMID:
10746727
3.

A role for alpha-synuclein in the regulation of dopamine biosynthesis.

Perez RG, Waymire JC, Lin E, Liu JJ, Guo F, Zigmond MJ.

J Neurosci. 2002 Apr 15;22(8):3090-9. Erratum in: J Neurosci 2002 Oct 15;22(20):9142.

5.

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10813-8.

7.

Does alpha-synuclein modulate dopaminergic synaptic content and tone at the synapse?

Sidhu A, Wersinger C, Vernier P.

FASEB J. 2004 Apr;18(6):637-47. Review.

PMID:
15054086
8.

Alpha-synuclein and Parkinson's disease.

Lücking CB, Brice A.

Cell Mol Life Sci. 2000 Dec;57(13-14):1894-908. Review.

PMID:
11215516
9.

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

Kirik D, Rosenblad C, Burger C, Lundberg C, Johansen TE, Muzyczka N, Mandel RJ, Björklund A.

J Neurosci. 2002 Apr 1;22(7):2780-91.

10.

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.

St Martin JL, Klucken J, Outeiro TF, Nguyen P, Keller-McGandy C, Cantuti-Castelvetri I, Grammatopoulos TN, Standaert DG, Hyman BT, McLean PJ.

J Neurochem. 2007 Mar;100(6):1449-57.

11.

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct.

Conway KA, Rochet JC, Bieganski RM, Lansbury PT Jr.

Science. 2001 Nov 9;294(5545):1346-9.

12.

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.

Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM.

Science. 2002 Feb 1;295(5556):865-8.

13.

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

Auluck PK, Meulener MC, Bonini NM.

J Biol Chem. 2005 Jan 28;280(4):2873-8.

14.

Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice.

Alerte TN, Akinfolarin AA, Friedrich EE, Mader SA, Hong CS, Perez RG.

Neurosci Lett. 2008 Apr 11;435(1):24-9. doi: 10.1016/j.neulet.2008.02.014.

15.

Interactions among alpha-synuclein, dopamine, and biomembranes: some clues for understanding neurodegeneration in Parkinson's disease.

Rochet JC, Outeiro TF, Conway KA, Ding TT, Volles MJ, Lashuel HA, Bieganski RM, Lindquist SL, Lansbury PT.

J Mol Neurosci. 2004;23(1-2):23-34. Review.

PMID:
15126689
16.

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.

Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, Iwatsubo T, Aebischer P.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17510-5.

17.

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, Przedborski S.

J Neurochem. 2000 Feb;74(2):721-9.

18.
19.

Occurrence of neuronal inclusions combined with increased nigral expression of alpha-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice.

Fornai F, Lenzi P, Ferrucci M, Lazzeri G, di Poggio AB, Natale G, Busceti CL, Biagioni F, Giusiani M, Ruggieri S, Paparelli A.

Brain Res Bull. 2005 May 15;65(5):405-13.

PMID:
15833595
20.

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

Zhou W, Hurlbert MS, Schaack J, Prasad KN, Freed CR.

Brain Res. 2000 Jun 2;866(1-2):33-43.

PMID:
10825478
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