Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 124

1.

Comparative study of the inhibition of metallo-beta-lactamases (IMP-1 and VIM-2) by thiol compounds that contain a hydrophobic group.

Jin W, Arakawa Y, Yasuzawa H, Taki T, Hashiguchi R, Mitsutani K, Shoga A, Yamaguchi Y, Kurosaki H, Shibata N, Ohta M, Goto M.

Biol Pharm Bull. 2004 Jun;27(6):851-6.

2.

Inhibition of metallo-beta-lactamases by a series of thiol ester derivatives of mercaptophenylacetic acid.

Payne DJ, Bateson JH, Gasson BC, Khushi T, Proctor D, Pearson SC, Reid R.

FEMS Microbiol Lett. 1997 Dec 1;157(1):171-5.

3.

Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.

Lassaux P, Hamel M, Gulea M, Delbrück H, Mercuri PS, Horsfall L, Dehareng D, Kupper M, Frère JM, Hoffmann K, Galleni M, Bebrone C.

J Med Chem. 2010 Jul 8;53(13):4862-76. doi: 10.1021/jm100213c.

PMID:
20527888
4.

Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-beta-lactamases.

Siemann S, Clarke AJ, Viswanatha T, Dmitrienko GI.

Biochemistry. 2003 Feb 18;42(6):1673-83.

PMID:
12578382
5.

Inhibition of IMP-1 metallo-beta-lactamase and sensitization of IMP-1-producing bacteria by thioester derivatives.

Hammond GG, Huber JL, Greenlee ML, Laub JB, Young K, Silver LL, Balkovec JM, Pryor KD, Wu JK, Leiting B, Pompliano DL, Toney JH.

FEMS Microbiol Lett. 1999 Oct 15;179(2):289-96.

6.

Irreversible inhibition of metallo-beta-lactamase (IMP-1) by 3-(3-mercaptopropionylsulfanyl)propionic acid pentafluorophenyl ester.

Kurosaki H, Yamaguchi Y, Higashi T, Soga K, Matsueda S, Yumoto H, Misumi S, Yamagata Y, Arakawa Y, Goto M.

Angew Chem Int Ed Engl. 2005 Jun 20;44(25):3861-4. No abstract available.

PMID:
15892033
7.

Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups.

Kurosaki H, Yamaguchi Y, Yasuzawa H, Jin W, Yamagata Y, Arakawa Y.

ChemMedChem. 2006 Sep;1(9):969-72. No abstract available.

PMID:
16937423
8.

Inhibition of the metallo-beta-lactamase produced from Serratia marcescens by thiol compounds.

Goto M, Takahashi T, Yamashita F, Koreeda A, Mori H, Ohta M, Arakawa Y.

Biol Pharm Bull. 1997 Nov;20(11):1136-40.

PMID:
9401719
9.

Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.

Greenlee ML, Laub JB, Balkovec JM, Hammond ML, Hammond GG, Pompliano DL, Epstein-Toney JH.

Bioorg Med Chem Lett. 1999 Sep 6;9(17):2549-54.

PMID:
10498206
10.

Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives.

Payne DJ, Bateson JH, Gasson BC, Proctor D, Khushi T, Farmer TH, Tolson DA, Bell D, Skett PW, Marshall AC, Reid R, Ghosez L, Combret Y, Marchand-Brynaert J.

Antimicrob Agents Chemother. 1997 Jan;41(1):135-40.

11.

Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor.

Yamaguchi Y, Jin W, Matsunaga K, Ikemizu S, Yamagata Y, Wachino J, Shibata N, Arakawa Y, Kurosaki H.

J Med Chem. 2007 Dec 27;50(26):6647-53. Epub 2007 Dec 6.

PMID:
18052313
12.

Postantibiotic and post-beta-lactamase inhibitor effect of carbapenems combined with EDTA against Pseudomonas aeruginosa strains producing VIM-metallo beta-lactamases.

Bedenić B, Vranes J, Sviben M, Beader N, Kalenić S.

Chemotherapy. 2008;54(3):188-93. doi: 10.1159/000140461. Epub 2008 Jun 18.

PMID:
18560225
13.

Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies.

Mollard C, Moali C, Papamicael C, Damblon C, Vessilier S, Amicosante G, Schofield CJ, Galleni M, Frere JM, Roberts GC.

J Biol Chem. 2001 Nov 30;276(48):45015-23. Epub 2001 Sep 19.

14.

Novel IMP-1 metallo-beta-lactamase inhibitors can reverse meropenem resistance in Escherichia coli expressing IMP-1.

Moloughney JG, D Thomas J, Toney JH.

FEMS Microbiol Lett. 2005 Feb 1;243(1):65-71.

15.

Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases.

Payne DJ, Hueso-Rodríguez JA, Boyd H, Concha NO, Janson CA, Gilpin M, Bateson JH, Cheever C, Niconovich NL, Pearson S, Rittenhouse S, Tew D, Díez E, Pérez P, De La Fuente J, Rees M, Rivera-Sagredo A.

Antimicrob Agents Chemother. 2002 Jun;46(6):1880-6.

16.

New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design.

Olsen L, Jost S, Adolph HW, Pettersson I, Hemmingsen L, Jørgensen FS.

Bioorg Med Chem. 2006 Apr 15;14(8):2627-35. Epub 2005 Dec 27.

PMID:
16378729
17.

Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases.

Simm AM, Loveridge EJ, Crosby J, Avison MB, Walsh TR, Bennett PM.

Biochem J. 2005 May 1;387(Pt 3):585-90.

18.

Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1.

Arjomandi OK, Hussein WM, Vella P, Yusof Y, Sidjabat HE, Schenk G, McGeary RP.

Eur J Med Chem. 2016 May 23;114:318-27. doi: 10.1016/j.ejmech.2016.03.017. Epub 2016 Mar 9.

PMID:
27017264
19.

Synthesis and kinetic testing of new inhibitors for a metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa.

Mohamed MS, Hussein WM, McGeary RP, Vella P, Schenk G, Abd El-Hameed RH.

Eur J Med Chem. 2011 Dec;46(12):6075-82. doi: 10.1016/j.ejmech.2011.10.030. Epub 2011 Oct 21.

PMID:
22051063
20.

Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.

Toney JH, Hammond GG, Fitzgerald PM, Sharma N, Balkovec JM, Rouen GP, Olson SH, Hammond ML, Greenlee ML, Gao YD.

J Biol Chem. 2001 Aug 24;276(34):31913-8. Epub 2001 Jun 4.

Supplemental Content

Support Center