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Items: 1 to 20 of 342

1.

AMPA receptor potentiators for the treatment of CNS disorders.

O'Neill MJ, Bleakman D, Zimmerman DM, Nisenbaum ES.

Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94. Review.

PMID:
15180479
2.

LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.

Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, Vandergriff JL, Baumbarger P, Siuda E, Gates M, Ogden AM, Skolnick P, Zimmerman DM, Nisenbaum ES, Bleakman D, O'Neill MJ.

J Pharmacol Exp Ther. 2003 Aug;306(2):752-62. Epub 2003 May 2.

PMID:
12730350
3.

LY404187: a novel positive allosteric modulator of AMPA receptors.

Quirk JC, Nisenbaum ES.

CNS Drug Rev. 2002 Fall;8(3):255-82. Review.

4.

LY503430: pharmacology, pharmacokinetics, and effects in rodent models of Parkinson's disease.

O'Neill MJ, Murray TK, Clay MP, Lindstrom T, Yang CR, Nisenbaum ES.

CNS Drug Rev. 2005 Spring;11(1):77-96. Review.

5.

AMPA receptor potentiators: application for depression and Parkinson's disease.

O'Neill MJ, Witkin JM.

Curr Drug Targets. 2007 May;8(5):603-20. Review.

PMID:
17504104
6.

Neurotrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease.

O'Neill MJ, Murray TK, Whalley K, Ward MA, Hicks CA, Woodhouse S, Osborne DJ, Skolnick P.

Eur J Pharmacol. 2004 Feb 20;486(2):163-74.

PMID:
14975705
7.
8.

AMPA receptor potentiators as cognitive enhancers.

O'Neill MJ, Dix S.

IDrugs. 2007 Mar;10(3):185-92. Review.

PMID:
17351873
9.

Brain-derived neurotrophic factor acutely enhances tyrosine phosphorylation of the AMPA receptor subunit GluR1 via NMDA receptor-dependent mechanisms.

Wu K, Len GW, McAuliffe G, Ma C, Tai JP, Xu F, Black IB.

Brain Res Mol Brain Res. 2004 Nov 4;130(1-2):178-86.

PMID:
15519688
10.

S18986: a positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures.

Lockhart BP, Rodriguez M, Mourlevat S, Peron P, Catesson S, Villain N, Galizzi JP, Boutin JA, Lestage P.

Eur J Pharmacol. 2007 Apr 30;561(1-3):23-31. Epub 2007 Feb 1.

PMID:
17331496
11.

A role for AMPA receptors in mood disorders.

Alt A, Nisenbaum ES, Bleakman D, Witkin JM.

Biochem Pharmacol. 2006 Apr 28;71(9):1273-88. Epub 2006 Jan 24. Review.

PMID:
16442080
12.

Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons.

Caldeira MV, Melo CV, Pereira DB, Carvalho R, Correia SS, Backos DS, Carvalho AL, Esteban JA, Duarte CB.

J Biol Chem. 2007 Apr 27;282(17):12619-28. Epub 2007 Mar 2. Erratum in: J Biol Chem. 2007 Sep 14;282(37):27556.

13.
14.

Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro.

Miu P, Jarvie KR, Radhakrishnan V, Gates MR, Ogden A, Ornstein PL, Zarrinmayeh H, Ho K, Peters D, Grabell J, Gupta A, Zimmerman DM, Bleakman D.

Neuropharmacology. 2001 Jun;40(8):976-83.

PMID:
11406188
15.

AMPA receptors in the therapeutic management of depression.

Bleakman D, Alt A, Witkin JM.

CNS Neurol Disord Drug Targets. 2007 Apr;6(2):117-26. Review.

PMID:
17430149
16.

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator.

Legutko B, Li X, Skolnick P.

Neuropharmacology. 2001 Jun;40(8):1019-27.

PMID:
11406193
17.
18.

Recent advances in positive allosteric modulators of the AMPA receptor.

Morrow JA, Maclean JK, Jamieson C.

Curr Opin Drug Discov Devel. 2006 Sep;9(5):571-9. Review.

PMID:
17002217
19.
20.

[Allosteric modulators of AMPA type glutamate receptors a novel gubclass of physiologically active substances].

RaevskiÄ­ KS, Eremin KO.

Biomed Khim. 2004;50(6):523-38. Review. Russian.

PMID:
15707268

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