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Items: 1 to 20 of 164

1.

Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.

Baird DM, Davis T, Rowson J, Jones CJ, Kipling D.

Hum Mol Genet. 2004 Jul 15;13(14):1515-24. Epub 2004 May 18.

PMID:
15150162
2.

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.

Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, Kipling D.

J Cell Sci. 2003 Apr 1;116(Pt 7):1349-57.

3.

Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells.

Kashino G, Kodama S, Nakayama Y, Suzuki K, Fukase K, Goto M, Watanabe M.

Free Radic Biol Med. 2003 Aug 15;35(4):438-43.

PMID:
12899945
4.
5.

Investigation of the signaling pathways involved in the proliferative life span barriers in werner syndrome fibroblasts.

Davis T, Faragher RG, Jones CJ, Kipling D.

Ann N Y Acad Sci. 2004 Jun;1019:274-7.

PMID:
15247028
6.

No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.

de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, Toussaint O.

Ann N Y Acad Sci. 2004 Jun;1019:375-8. Review.

PMID:
15247048
7.

Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans.

Britt-Compton B, Rowson J, Locke M, Mackenzie I, Kipling D, Baird DM.

Hum Mol Genet. 2006 Mar 1;15(5):725-33. Epub 2006 Jan 18.

PMID:
16421168
8.

Accumulation of short telomeres in human fibroblasts prior to replicative senescence.

Martens UM, Chavez EA, Poon SS, Schmoor C, Lansdorp PM.

Exp Cell Res. 2000 Apr 10;256(1):291-9.

PMID:
10739676
9.

Extensive allelic variation and ultrashort telomeres in senescent human cells.

Baird DM, Rowson J, Wynford-Thomas D, Kipling D.

Nat Genet. 2003 Feb;33(2):203-7. Epub 2003 Jan 21.

PMID:
12539050
10.

Early-senescing human skin fibroblasts do not demonstrate accelerated telomere shortening.

Ferenac M, Polancec D, Huzak M, Pereira-Smith OM, Rubelj I.

J Gerontol A Biol Sci Med Sci. 2005 Jul;60(7):820-9.

PMID:
16079203
11.

Low oxygen delays fibroblast senescence despite shorter telomeres.

Betts DH, Perrault SD, King WA.

Biogerontology. 2008 Feb;9(1):19-31. Epub 2007 Oct 20.

PMID:
17952625
12.

Proliferation dynamics in cultured skin fibroblasts from Down syndrome subjects.

Kimura M, Cao X, Skurnick J, Cody M, Soteropoulos P, Aviv A.

Free Radic Biol Med. 2005 Aug 1;39(3):374-80. Epub 2005 Apr 8.

PMID:
15993336
13.

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

von Zglinicki T, Pilger R, Sitte N.

Free Radic Biol Med. 2000 Jan 1;28(1):64-74.

PMID:
10656292
14.

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells.

Schulz VP, Zakian VA, Ogburn CE, McKay J, Jarzebowicz AA, Edland SD, Martin GM.

Hum Genet. 1996 Jun;97(6):750-4.

PMID:
8641691
15.

Accelerated telomere shortening in fibroblasts after extended periods of confluency.

Sitte N, Saretzki G, von Zglinicki T.

Free Radic Biol Med. 1998 Apr;24(6):885-93.

PMID:
9607597
16.

Werner syndrome and biological ageing: a molecular genetic hypothesis.

Thweatt R, Goldstein S.

Bioessays. 1993 Jun;15(6):421-6. Review.

PMID:
8357345
17.

Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span.

Martin-Ruiz C, Saretzki G, Petrie J, Ladhoff J, Jeyapalan J, Wei W, Sedivy J, von Zglinicki T.

J Biol Chem. 2004 Apr 23;279(17):17826-33. Epub 2004 Feb 12.

18.

Telomere shortening does not occur during postmaturational aging in situ in normal human oral fibroblasts.

Kang MK, Kameta A, Baluda MA, Park NH.

Mech Ageing Dev. 2003 Aug-Sep;124(8-9):873-6.

PMID:
14499491
19.

Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?

von Zglinicki T, Saretzki G, Döcke W, Lotze C.

Exp Cell Res. 1995 Sep;220(1):186-93.

PMID:
7664835
20.

Erosion of the telomeric single-strand overhang at replicative senescence.

Stewart SA, Ben-Porath I, Carey VJ, O'Connor BF, Hahn WC, Weinberg RA.

Nat Genet. 2003 Apr;33(4):492-6. Epub 2003 Mar 24.

PMID:
12652299

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