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Items: 1 to 20 of 114

1.

Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver.

Jadhao SB, Yang RZ, Lin Q, Hu H, Anania FA, Shuldiner AR, Gong DW.

Hepatology. 2004 May;39(5):1297-302. Erratum in: Hepatology. 2004 Jul;40(1):269. Jadaho Sanjay B [corrected to Jadhao Sanjay B].

PMID:
15122758
2.

cDNA cloning, expression, purification, distribution, and characterization of biologically active canine alanine aminotransferase-1.

Rajamohan F, Nelms L, Joslin DL, Lu B, Reagan WJ, Lawton M.

Protein Expr Purif. 2006 Jul;48(1):81-9. Epub 2006 Jan 30.

PMID:
16495081
3.

cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase.

Yang RZ, Blaileanu G, Hansen BC, Shuldiner AR, Gong DW.

Genomics. 2002 Mar;79(3):445-50.

PMID:
11863375
4.

Alanine aminotransferase isoenzymes: molecular cloning and quantitative analysis of tissue expression in rats and serum elevation in liver toxicity.

Yang RZ, Park S, Reagan WJ, Goldstein R, Zhong S, Lawton M, Rajamohan F, Qian K, Liu L, Gong DW.

Hepatology. 2009 Feb;49(2):598-607. doi: 10.1002/hep.22657.

5.

Isoforms of alanine aminotransferases in human tissues and serum--differential tissue expression using novel antibodies.

Lindblom P, Rafter I, Copley C, Andersson U, Hedberg JJ, Berg AL, Samuelsson A, Hellmold H, Cotgreave I, Glinghammar B.

Arch Biochem Biophys. 2007 Oct 1;466(1):66-77. Epub 2007 Aug 11.

PMID:
17826732
6.

Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.

Rafter I, Gråberg T, Kotronen A, Strömmer L, Mattson CM, Kim RW, Ehrenborg E, Andersson HB, Yki-Järvinen H, Schuppe-Koistinen I, Ekblom B, Cotgreave I, Glinghammar B.

Int J Mol Med. 2012 Nov;30(5):1241-9. doi: 10.3892/ijmm.2012.1106. Epub 2012 Aug 23.

PMID:
22922605
7.

Increased hepatic expression is a major determinant of serum alanine aminotransferase elevation in mice with nonalcoholic steatohepatitis.

Liu R, Pan X, Whitington PF.

Liver Int. 2009 Mar;29(3):337-43. doi: 10.1111/j.1478-3231.2008.01862.x. Epub 2008 Aug 14.

PMID:
18710424
8.

Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury.

Miyazaki M, Rosenblum JS, Kasahara Y, Nakagawa I, Patricelli MP.

J Pharmacol Toxicol Methods. 2009 Nov-Dec;60(3):307-15. doi: 10.1016/j.vascn.2009.09.001. Epub 2009 Sep 11.

PMID:
19748590
9.

An ancient molecule with novel function: Alanine aminotransferase as a lipopolysaccharide binding protein with bacteriocidal activity.

Jing X, Zhang S.

Dev Comp Immunol. 2011 Jan;35(1):94-104. doi: 10.1016/j.dci.2010.08.014. Epub 2010 Sep 21.

PMID:
20816894
10.

Expression, purification, and initial characterization of human alanine aminotransferase (ALT) isoenzyme 1 and 2 in High-five insect cells.

Liu L, Zhong S, Yang R, Hu H, Yu D, Zhu D, Hua Z, Shuldiner AR, Goldstein R, Reagan WJ, Gong DW.

Protein Expr Purif. 2008 Aug;60(2):225-31. doi: 10.1016/j.pep.2008.04.006. Epub 2008 Apr 26.

11.

[Expression of recombinant human alanine aminotransferase (ALT) isoenzyme 2 and preparation of anti-ALT2 monoclonal antibody].

Ge C, Xian YL, Liao HM, Bao YG, Ye XZ, Li YM, Xia HZ.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010 Dec;26(12):1232-4, 1237. Chinese.

PMID:
21138690
12.
13.

Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level.

Qian K, Zhong S, Xie K, Yu D, Yang R, Gong DW.

Diabetes Metab Res Rev. 2015 Sep;31(6):562-71. doi: 10.1002/dmrr.2655. Epub 2015 Jun 17.

14.

Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver.

Yu S, Viswakarma N, Batra SK, Sambasiva Rao M, Reddy JK.

Biochimie. 2004 Nov;86(11):743-61.

PMID:
15589683
15.

Detection of the mitochondrial and catalytically active alanine aminotransferase in human tissues and plasma.

Glinghammar B, Rafter I, Lindström AK, Hedberg JJ, Andersson HB, Lindblom P, Berg AL, Cotgreave I.

Int J Mol Med. 2009 May;23(5):621-31.

PMID:
19360321
16.

Serum alanine aminotransferase activity in obese children.

Tazawa Y, Noguchi H, Nishinomiya F, Takada G.

Acta Paediatr. 1997 Mar;86(3):238-41.

PMID:
9099310
17.

Paralogous ALT1 and ALT2 retention and diversification have generated catalytically active and inactive aminotransferases in Saccharomyces cerevisiae.

Peñalosa-Ruiz G, Aranda C, Ongay-Larios L, Colon M, Quezada H, Gonzalez A.

PLoS One. 2012;7(9):e45702. doi: 10.1371/journal.pone.0045702. Epub 2012 Sep 25.

18.

Metabolic adaptive ALT isoenzyme response in livers of C57/BL6 mice treated with dexamethasone.

Reagan WJ, Yang RZ, Park S, Goldstein R, Brees D, Gong DW.

Toxicol Pathol. 2012 Dec;40(8):1117-27. doi: 10.1177/0192623312447550. Epub 2012 May 18.

19.

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.

20.

A novel aminosterol reverses diabetes and fatty liver disease in obese mice.

Takahashi N, Qi Y, Patel HR, Ahima RS.

J Hepatol. 2004 Sep;41(3):391-8.

PMID:
15336441

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