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Items: 1 to 20 of 282

1.

Fluorine in medicinal chemistry.

Böhm HJ, Banner D, Bendels S, Kansy M, Kuhn B, Müller K, Obst-Sander U, Stahl M.

Chembiochem. 2004 May 3;5(5):637-43. Review.

PMID:
15122635
2.

The role of fluorine in medicinal chemistry.

Shah P, Westwell AD.

J Enzyme Inhib Med Chem. 2007 Oct;22(5):527-40. Review.

PMID:
18035820
3.

From drug target to leads--sketching a physicochemical pathway for lead molecule design in silico.

Shaikh SA, Jain T, Sandhu G, Latha N, Jayaram B.

Curr Pharm Des. 2007;13(34):3454-70. Review.

PMID:
18220783
4.

Intramolecular hydrogen bonding in medicinal chemistry.

Kuhn B, Mohr P, Stahl M.

J Med Chem. 2010 Mar 25;53(6):2601-11. doi: 10.1021/jm100087s.

PMID:
20175530
5.

Fluorine bonding--how does it work in protein-ligand interactions?

Zhou P, Zou J, Tian F, Shang Z.

J Chem Inf Model. 2009 Oct;49(10):2344-55. doi: 10.1021/ci9002393.

PMID:
19788294
6.

Physics-based methods for studying protein-ligand interactions.

Huang N, Jacobson MP.

Curr Opin Drug Discov Devel. 2007 May;10(3):325-31. Review.

PMID:
17554859
7.

Virtual high-throughput screening of molecular databases.

Seifert MH, Kraus J, Kramer B.

Curr Opin Drug Discov Devel. 2007 May;10(3):298-307. Review.

PMID:
17554856
8.

Molecular modeling of hydration in drug design.

Mancera RL.

Curr Opin Drug Discov Devel. 2007 May;10(3):275-80. Review.

PMID:
17554853
9.
10.

Informatics and modeling challenges in fragment-based drug discovery.

Hubbard RE, Chen I, Davis B.

Curr Opin Drug Discov Devel. 2007 May;10(3):289-97. Review.

PMID:
17554855
11.
12.
13.

Protein NMR-based screening in drug discovery.

Zartler ER, Shapiro MJ.

Curr Pharm Des. 2006;12(31):3963-72. Review.

PMID:
17100607
14.

Metal complexes in medicinal chemistry: new vistas and challenges in drug design.

Thompson KH, Orvig C.

Dalton Trans. 2006 Feb 14;(6):761-4. Epub 2005 Nov 23.

PMID:
16437168
15.

Fluorine in pharmaceuticals: looking beyond intuition.

Müller K, Faeh C, Diederich F.

Science. 2007 Sep 28;317(5846):1881-6. Review.

PMID:
17901324
16.

Fluorine in medicinal chemistry.

Swallow S.

Prog Med Chem. 2015;54:65-133. doi: 10.1016/bs.pmch.2014.11.001. Epub 2015 Jan 7. Review.

PMID:
25727703
17.

Lead optimization via high-throughput molecular docking.

Joseph-McCarthy D, Baber JC, Feyfant E, Thompson DC, Humblet C.

Curr Opin Drug Discov Devel. 2007 May;10(3):264-74. Review.

PMID:
17554852
18.

Structure-based druggability assessment--identifying suitable targets for small molecule therapeutics.

Fauman EB, Rai BK, Huang ES.

Curr Opin Chem Biol. 2011 Aug;15(4):463-8. doi: 10.1016/j.cbpa.2011.05.020. Epub 2011 Jun 23. Review.

PMID:
21704549
19.

Structural biology and drug discovery.

Scapin G.

Curr Pharm Des. 2006;12(17):2087-97. Review.

PMID:
16796557
20.

Ranking poses in structure-based lead discovery and optimization: current trends in scoring function development.

Rajamani R, Good AC.

Curr Opin Drug Discov Devel. 2007 May;10(3):308-15. Review.

PMID:
17554857

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