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Items: 1 to 20 of 293

1.

5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN.

J Cell Biochem. 2004 May 15;92(2):316-31.

PMID:
15108358
2.

PTHrP expression in chick sternal chondrocytes is regulated by TGF-beta through Smad-mediated signaling.

Pateder DB, Ferguson CM, Ionescu AM, Schwarz EM, Rosier RN, Puzas JE, O'Keefe RJ.

J Cell Physiol. 2001 Sep;188(3):343-51.

PMID:
11473361
3.

Lead alters parathyroid hormone-related peptide and transforming growth factor-beta1 effects and AP-1 and NF-kappaB signaling in chondrocytes.

Zuscik MJ, Pateder DB, Puzas JE, Schwarz EM, Rosier RN, O'Keefe RJ.

J Orthop Res. 2002 Jul;20(4):811-8.

4.

Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

Valcourt U, Gouttenoire J, Moustakas A, Herbage D, Mallein-Gerin F.

J Biol Chem. 2002 Sep 13;277(37):33545-58. Epub 2002 Jun 24.

5.

CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter.

Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ.

J Cell Physiol. 2004 Mar;198(3):428-40.

PMID:
14755548
6.

Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.

Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ.

J Cell Biochem. 2003 Dec 15;90(6):1287-98.

PMID:
14635200
7.

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog.

Grimsrud CD, Romano PR, D'Souza M, Puzas JE, Schwarz EM, Reynolds PR, Roiser RN, O'Keefe RJ.

J Orthop Res. 2001 Jan;19(1):18-25.

9.

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.

Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ.

J Bone Miner Res. 2003 Sep;18(9):1593-604.

10.

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification.

Sakou T, Onishi T, Yamamoto T, Nagamine T, Sampath Tk, Ten Dijke P.

J Bone Miner Res. 1999 Jul;14(7):1145-52.

11.

The bone morphogenetic protein 2 signaling mediator Smad1 participates predominantly in osteogenic and not in chondrogenic differentiation in mesenchymal progenitors C3H10T1/2.

Ju W, Hoffmann A, Verschueren K, Tylzanowski P, Kaps C, Gross G, Huylebroeck D.

J Bone Miner Res. 2000 Oct;15(10):1889-99.

12.

ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation.

Ionescu AM, Schwarz EM, Zuscik MJ, Drissi H, Puzas JE, Rosier RN, O'Keefe RJ.

Exp Cell Res. 2003 Aug 1;288(1):198-207.

PMID:
12878171
13.
14.

Growth plate chondrocyte maturation is regulated by basal intracellular calcium.

Zuscik MJ, D'Souza M, Ionescu AM, Gunter KK, Gunter TE, O'Keefe RJ, Schwarz EM, Puzas JE, Rosier RN.

Exp Cell Res. 2002 Jun 10;276(2):310-9. Erratum in: Exp Cell Res 2002 Jul 15;277(2):233.

PMID:
12027460
15.

Engagement of activin and bone morphogenetic protein signaling pathway Smad proteins in the induction of inhibin B production in ovarian granulosa cells.

Bondestam J, Kaivo-oja N, Kallio J, Groome N, Hydén-Granskog C, Fujii M, Moustakas A, Jalanko A, ten Dijke P, Ritvos O.

Mol Cell Endocrinol. 2002 Sep 30;195(1-2):79-88.

PMID:
12354674
16.

Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

Pardali K, Kowanetz M, Heldin CH, Moustakas A.

J Cell Physiol. 2005 Jul;204(1):260-72.

PMID:
15690394
17.

TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition.

Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A.

Mol Biol Cell. 2005 Apr;16(4):1987-2002. Epub 2005 Feb 2.

18.

Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.

Li X, Ionescu AM, Schwarz EM, Zhang X, Drissi H, Puzas JE, Rosier RN, Zuscik MJ, O'Keefe RJ.

J Orthop Res. 2003 Sep;21(5):908-13.

19.

Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.

Li TF, Darowish M, Zuscik MJ, Chen D, Schwarz EM, Rosier RN, Drissi H, O'Keefe RJ.

J Bone Miner Res. 2006 Jan;21(1):4-16. Epub 2005 Sep 19.

20.

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation.

Gaur T, Rich L, Lengner CJ, Hussain S, Trevant B, Ayers D, Stein JL, Bodine PV, Komm BS, Stein GS, Lian JB.

J Cell Physiol. 2006 Jul;208(1):87-96.

PMID:
16575902

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