Similar articles for PMID: 15105103

Year	Number of Results
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1

Identification and characterization of inhibitors of bacterial enoyl-acyl carrier protein reductase.

Ling LL, Xian J, Ali S, Geng B, Fan J, Mills DM, Arvanites AC, Orgueira H, Ashwell MA, Carmel G, Xiang Y, Moir DT. Ling LL, et al. Antimicrob Agents Chemother. 2004 May;48(5):1541-7. doi: 10.1128/AAC.48.5.1541-1547.2004. Antimicrob Agents Chemother. 2004. PMID: 15105103 Free PMC article.

2

The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

Bergler H, Fuchsbichler S, Högenauer G, Turnowsky F. Bergler H, et al. Eur J Biochem. 1996 Dec 15;242(3):689-94. doi: 10.1111/j.1432-1033.1996.0689r.x. Eur J Biochem. 1996. PMID: 9022698 Free article.

3

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents.

Seefeld MA, Miller WH, Newlander KA, Burgess WJ, Payne DJ, Rittenhouse SF, Moore TD, DeWolf WE Jr, Keller PM, Qiu X, Janson CA, Vaidya K, Fosberry AP, Smyth MG, Jaworski DD, Slater-Radosti C, Huffman WF. Seefeld MA, et al. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2241-4. doi: 10.1016/s0960-894x(01)00405-x. Bioorg Med Chem Lett. 2001. PMID: 11527706

4

Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).

Miller WH, Seefeld MA, Newlander KA, Uzinskas IN, Burgess WJ, Heerding DA, Yuan CC, Head MS, Payne DJ, Rittenhouse SF, Moore TD, Pearson SC, Berry V, DeWolf WE Jr, Keller PM, Polizzi BJ, Qiu X, Janson CA, Huffman WF. Miller WH, et al. J Med Chem. 2002 Jul 18;45(15):3246-56. doi: 10.1021/jm020050+. J Med Chem. 2002. PMID: 12109908

5

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI).

Heerding DA, Chan G, DeWolf WE, Fosberry AP, Janson CA, Jaworski DD, McManus E, Miller WH, Moore TD, Payne DJ, Qiu X, Rittenhouse SF, Slater-Radosti C, Smith W, Takata DT, Vaidya KS, Yuan CC, Huffman WF. Heerding DA, et al. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2061-5. doi: 10.1016/s0960-894x(01)00404-8. Bioorg Med Chem Lett. 2001. PMID: 11514139

6

Structural basis and mechanism of enoyl reductase inhibition by triclosan.

Stewart MJ, Parikh S, Xiao G, Tonge PJ, Kisker C. Stewart MJ, et al. J Mol Biol. 1999 Jul 23;290(4):859-65. doi: 10.1006/jmbi.1999.2907. J Mol Biol. 1999. PMID: 10398587

7

Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.

Lu H, Tonge PJ. Lu H, et al. Acc Chem Res. 2008 Jan;41(1):11-20. doi: 10.1021/ar700156e. Acc Chem Res. 2008. PMID: 18193820 Review.

8

Phenylimidazole derivatives as specific inhibitors of bacterial enoyl-acyl carrier protein reductase FabK.

Ozawa T, Kitagawa H, Yamamoto Y, Takahata S, Iida M, Osaki Y, Yamada K. Ozawa T, et al. Bioorg Med Chem. 2007 Dec 1;15(23):7325-36. doi: 10.1016/j.bmc.2007.08.050. Epub 2007 Sep 4. Bioorg Med Chem. 2007. PMID: 17892940

9

Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of β-oxidation cycle.

Vick JE, Clomburg JM, Blankschien MD, Chou A, Kim S, Gonzalez R. Vick JE, et al. Appl Environ Microbiol. 2015 Feb;81(4):1406-16. doi: 10.1128/AEM.03521-14. Appl Environ Microbiol. 2015. PMID: 25527535 Free PMC article.

10

Molecular genetic analysis of enoyl-acyl carrier protein reductase inhibition by diazaborine.

de Boer GJ, Pielage GJ, Nijkamp HJ, Slabas AR, Rafferty JB, Baldock C, Rice DW, Stuitje AR. de Boer GJ, et al. Mol Microbiol. 1999 Jan;31(2):443-50. doi: 10.1046/j.1365-2958.1999.01182.x. Mol Microbiol. 1999. PMID: 10027962 Free article.

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