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Items: 1 to 20 of 346

1.
3.

Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.

Borra MT, Langer MR, Slama JT, Denu JM.

Biochemistry. 2004 Aug 3;43(30):9877-87.

PMID:
15274642
4.

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.

Zhao K, Harshaw R, Chai X, Marmorstein R.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8563-8.

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6.

Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.

Sauve AA, Celic I, Avalos J, Deng H, Boeke JD, Schramm VL.

Biochemistry. 2001 Dec 25;40(51):15456-63.

PMID:
11747420
7.
8.

Structural basis for the NAD-dependent deacetylase mechanism of Sir2.

Chang JH, Kim HC, Hwang KY, Lee JW, Jackson SP, Bell SD, Cho Y.

J Biol Chem. 2002 Sep 13;277(37):34489-98.

9.

Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases.

Jackson MD, Schmidt MT, Oppenheimer NJ, Denu JM.

J Biol Chem. 2003 Dec 19;278(51):50985-98.

12.

Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.

Borra MT, O'Neill FJ, Jackson MD, Marshall B, Verdin E, Foltz KR, Denu JM.

J Biol Chem. 2002 Apr 12;277(15):12632-41.

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Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition.

Sauve AA, Moir RD, Schramm VL, Willis IM.

Mol Cell. 2005 Feb 18;17(4):595-601.

15.

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins.

Landry J, Slama JT, Sternglanz R.

Biochem Biophys Res Commun. 2000 Nov 30;278(3):685-90.

PMID:
11095969
16.

Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.

Marmorstein R.

Biochem Soc Trans. 2004 Dec;32(Pt 6):904-9. Review.

PMID:
15506920
17.

Human Sir2 and the 'silencing' of p53 activity.

Smith J.

Trends Cell Biol. 2002 Sep;12(9):404-6.

PMID:
12220851
18.

Acetylation-dependent ADP-ribosylation by Trypanosoma brucei Sir2.

Kowieski TM, Lee S, Denu JM.

J Biol Chem. 2008 Feb 29;283(9):5317-26. doi: 10.1074/jbc.M707613200.

19.

Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

Du J, Jiang H, Lin H.

Biochemistry. 2009 Apr 7;48(13):2878-90. doi: 10.1021/bi802093g.

PMID:
19220062
20.

The Sir2 family of protein deacetylases.

Blander G, Guarente L.

Annu Rev Biochem. 2004;73:417-35. Review.

PMID:
15189148
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