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Items: 1 to 20 of 211

1.

Structural basis for amplifying vinculin activation by talin.

Izard T, Vonrhein C.

J Biol Chem. 2004 Jun 25;279(26):27667-78. Epub 2004 Apr 7.

2.

Vinculin activation by talin through helical bundle conversion.

Izard T, Evans G, Borgon RA, Rush CL, Bricogne G, Bois PR.

Nature. 2004 Jan 8;427(6970):171-5. Epub 2003 Dec 31.

PMID:
14702644
3.

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

Fillingham I, Gingras AR, Papagrigoriou E, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL.

Structure. 2005 Jan;13(1):65-74.

4.

Rhombohedral crystals of the human vinculin head domain in complex with a vinculin-binding site of talin.

Rush CL, Izard T.

Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):945-7. Epub 2004 Apr 21.

PMID:
15103147
5.

Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

Cohen DM, Chen H, Johnson RP, Choudhury B, Craig SW.

J Biol Chem. 2005 Apr 29;280(17):17109-17. Epub 2005 Feb 22.

6.

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

Gingras AR, Ziegler WH, Frank R, Barsukov IL, Roberts GC, Critchley DR, Emsley J.

J Biol Chem. 2005 Nov 4;280(44):37217-24. Epub 2005 Aug 30.

7.

The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.

Bois PR, O'Hara BP, Nietlispach D, Kirkpatrick J, Izard T.

J Biol Chem. 2006 Mar 17;281(11):7228-36. Epub 2006 Jan 9.

8.

Structural and dynamic characterization of a vinculin binding site in the talin rod.

Gingras AR, Vogel KP, Steinhoff HJ, Ziegler WH, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL.

Biochemistry. 2006 Feb 14;45(6):1805-17.

PMID:
16460027
9.

Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.

Yogesha SD, Rangarajan ES, Vonrhein C, Bricogne G, Izard T.

Protein Sci. 2012 Apr;21(4):583-8. doi: 10.1002/pro.2041. Epub 2012 Feb 28.

10.

The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.

Patel B, Gingras AR, Bobkov AA, Fujimoto LM, Zhang M, Liddington RC, Mazzeo D, Emsley J, Roberts GC, Barsukov IL, Critchley DR.

J Biol Chem. 2006 Mar 17;281(11):7458-67. Epub 2006 Jan 9.

11.

Integrin connections to the cytoskeleton through talin and vinculin.

Ziegler WH, Gingras AR, Critchley DR, Emsley J.

Biochem Soc Trans. 2008 Apr;36(Pt 2):235-9. doi: 10.1042/BST0360235. Review.

PMID:
18363566
12.

Coincidence of actin filaments and talin is required to activate vinculin.

Chen H, Choudhury DM, Craig SW.

J Biol Chem. 2006 Dec 29;281(52):40389-98. Epub 2006 Oct 29.

13.

Crystal structure of the talin integrin binding domain 2.

Cheung TY, Fairchild MJ, Zarivach R, Tanentzapf G, Van Petegem F.

J Mol Biol. 2009 Apr 10;387(4):787-93.

PMID:
19340939
14.

Crystal structure of human vinculin.

Borgon RA, Vonrhein C, Bricogne G, Bois PR, Izard T.

Structure. 2004 Jul;12(7):1189-97. Epub 2004 Jun 3.

15.

RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL.

J Biol Chem. 2013 Mar 22;288(12):8238-49. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6.

16.

Further characterization of the interaction between the cytoskeletal proteins talin and vinculin.

Bass MD, Patel B, Barsukov IG, Fillingham IJ, Mason R, Smith BJ, Bagshaw CR, Critchley DR.

Biochem J. 2002 Mar 15;362(Pt 3):761-8.

17.

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain.

Tremuth L, Kreis S, Melchior C, Hoebeke J, Rondé P, Plançon S, Takeda K, Kieffer N.

J Biol Chem. 2004 May 21;279(21):22258-66. Epub 2004 Mar 18.

18.

Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix.

Bass MD, Smith BJ, Prigent SA, Critchley DR.

Biochem J. 1999 Jul 15;341 ( Pt 2):257-63.

19.

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle.

Papagrigoriou E, Gingras AR, Barsukov IL, Bate N, Fillingham IJ, Patel B, Frank R, Ziegler WH, Roberts GC, Critchley DR, Emsley J.

EMBO J. 2004 Aug 4;23(15):2942-51. Epub 2004 Jul 22.

20.

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.

Critchley DR.

Biochem Soc Trans. 2004 Nov;32(Pt 5):831-6. Review.

PMID:
15494027

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