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Control of Leishmania major in the absence of Tyk2 kinase.

Schleicher U, Mattner J, Blos M, Schindler H, Röllinghoff M, Karaghiosoff M, Müller M, Werner-Felmayer G, Bogdan C.

Eur J Immunol. 2004 Feb;34(2):519-29.


Requirement for type 2 NO synthase for IL-12 signaling in innate immunity.

Diefenbach A, Schindler H, Röllinghoff M, Yokoyama WM, Bogdan C.

Science. 1999 May 7;284(5416):951-5. Erratum in: Science 1999 Jun 11;284(5421):1776.


STAT-4 mediated IL-12 signaling pathway is critical for the development of protective immunity in cutaneous leishmaniasis.

Stamm LM, Satoskar AA, Ghosh SK, David JR, Satoskar AR.

Eur J Immunol. 1999 Aug;29(8):2524-9.


Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection.

Bihl F, Pecheur J, Bréart B, Poupon G, Cazareth J, Julia V, Glaichenhaus N, Braud VM.

J Immunol. 2010 Aug 15;185(4):2174-81. doi: 10.4049/jimmunol.1001486. Epub 2010 Jul 12.


IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms.

Lucas S, Ghilardi N, Li J, de Sauvage FJ.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15047-52. Epub 2003 Dec 1.


TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis.

Liese J, Schleicher U, Bogdan C.

Eur J Immunol. 2007 Dec;37(12):3424-34.


Protection against progressive leishmaniasis by IFN-beta.

Mattner J, Wandersee-Steinhäuser A, Pahl A, Röllinghoff M, Majeau GR, Hochman PS, Bogdan C.

J Immunol. 2004 Jun 15;172(12):7574-82.


Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection.

Satoskar AR, Stamm LM, Zhang X, Satoskar AA, Okano M, Terhorst C, David JR, Wang B.

J Immunol. 1999 Jun 1;162(11):6747-54.


[TH1 response in the experimental infection with Trypanosoma cruzi].

Cardoni RL, Antúnez MI, Abrami AA.

Medicina (B Aires). 1999;59 Suppl 2:84-90. Spanish.


Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice.

Rocha FJ, Schleicher U, Mattner J, Alber G, Bogdan C.

Infect Immun. 2007 Aug;75(8):3823-32. Epub 2007 May 21.


IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis.

Scharton-Kersten T, Afonso LC, Wysocka M, Trinchieri G, Scott P.

J Immunol. 1995 May 15;154(10):5320-30.


Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways.

Lawless VA, Zhang S, Ozes ON, Bruns HA, Oldham I, Hoey T, Grusby MJ, Kaplan MH.

J Immunol. 2000 Dec 15;165(12):6803-8.


Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1-mediated IFN signaling pathway.

Rosas LE, Keiser T, Pyles R, Durbin J, Satoskar AR.

Eur J Immunol. 2003 Jul;33(7):1799-805.


Development of Th1 and not Th2 immune responses in mice lacking IFN-regulatory factor-4.

Tominaga N, Ohkusu-Tsukada K, Udono H, Abe R, Matsuyama T, Yui K.

Int Immunol. 2003 Jan;15(1):1-10.


Control of New World cutaneous leishmaniasis is IL-12 independent but STAT4 dependent.

Buxbaum LU, Uzonna JE, Goldschmidt MH, Scott P.

Eur J Immunol. 2002 Nov;32(11):3206-15.


Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

Radwanska M, Cutler AJ, Hoving JC, Magez S, Holscher C, Bohms A, Arendse B, Kirsch R, Hunig T, Alexander J, Kaye P, Brombacher F.

PLoS Pathog. 2007 May 11;3(5):e68.


Notch1 expression on T cells is not required for CD4+ T helper differentiation.

Tacchini-Cottier F, Allenbach C, Otten LA, Radtke F.

Eur J Immunol. 2004 Jun;34(6):1588-96.


Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice.

Shimoda K, Tsutsui H, Aoki K, Kato K, Matsuda T, Numata A, Takase K, Yamamoto T, Nukina H, Hoshino T, Asano Y, Gondo H, Okamura T, Okamura S, Nakayama K, Nakanishi K, Niho Y, Harada M.

Blood. 2002 Mar 15;99(6):2094-9.


NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major.

Artis D, Speirs K, Joyce K, Goldschmidt M, Caamaño J, Hunter CA, Scott P.

J Immunol. 2003 Feb 15;170(4):1995-2003.


A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis.

Ortmann R, Smeltz R, Yap G, Sher A, Shevach EM.

J Immunol. 2001 May 1;166(9):5712-9.

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