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Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways.

Zimmermann N, Mishra A, King NE, Fulkerson PC, Doepker MP, Nikolaidis NM, Kindinger LE, Moulton EA, Aronow BJ, Rothenberg ME.

J Immunol. 2004 Feb 1;172(3):1815-24.


Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma.

Fulkerson PC, Zimmermann N, Hassman LM, Finkelman FD, Rothenberg ME.

J Immunol. 2004 Dec 15;173(12):7565-74.


Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression.

Zimmermann N, Hogan SP, Mishra A, Brandt EB, Bodette TR, Pope SM, Finkelman FD, Rothenberg ME.

J Immunol. 2000 Nov 15;165(10):5839-46.


Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung.

Follettie MT, Ellis DK, Donaldson DD, Hill AA, Diesl V, DeClercq C, Sypek JP, Dorner AJ, Wills-Karp M.

Pharmacogenomics J. 2006 Mar-Apr;6(2):141-52.


Identification of novel IL-4/Stat6-regulated genes in T lymphocytes.

Chen Z, Lund R, Aittokallio T, Kosonen M, Nevalainen O, Lahesmaa R.

J Immunol. 2003 Oct 1;171(7):3627-35.


Trefoil factor-2 is an allergen-induced gene regulated by Th2 cytokines and STAT6 in the lung.

Nikolaidis NM, Zimmermann N, King NE, Mishra A, Pope SM, Finkelman FD, Rothenberg ME.

Am J Respir Cell Mol Biol. 2003 Oct;29(4):458-64. Epub 2003 Apr 17.


Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study.

Hirota JA, Ask K, Fritz D, Ellis R, Wattie J, Richards CD, Labiris R, Kolb M, Inman MD.

Clin Exp Allergy. 2009 Jan;39(1):147-58. doi: 10.1111/j.1365-2222.2008.03109.x. Epub 2008 Oct 11.


Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma.

King NE, Zimmermann N, Pope SM, Fulkerson PC, Nikolaidis NM, Mishra A, Witte DP, Rothenberg ME.

Am J Respir Cell Mol Biol. 2004 Sep;31(3):257-65. Epub 2004 Apr 15.


Genome-wide profiling of antigen-induced time course expression using murine models for acute and chronic asthma.

Park SG, Choi JW, Kim Hj, Roh GS, Bok J, Go MJ, Kwack K, Oh B, Kim Y.

Int Arch Allergy Immunol. 2008;146(1):44-56. Epub 2007 Dec 14.


STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation.

Hoshino A, Tsuji T, Matsuzaki J, Jinushi T, Ashino S, Teramura T, Chamoto K, Tanaka Y, Asakura Y, Sakurai T, Mita Y, Takaoka A, Nakaike S, Takeshima T, Ikeda H, Nishimura T.

Int Immunol. 2004 Oct;16(10):1497-505. Epub 2004 Sep 6.


Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses.

Akei HS, Brandt EB, Mishra A, Strait RT, Finkelman FD, Warrier MR, Hershey GK, Blanchard C, Rothenberg ME.

J Allergy Clin Immunol. 2006 Jul;118(1):62-9. Epub 2006 Jun 9.


Suppressive effect of IL-4 on IL-13-induced genes in mouse lung.

Finkelman FD, Yang M, Perkins C, Schleifer K, Sproles A, Santeliz J, Bernstein JA, Rothenberg ME, Morris SC, Wills-Karp M.

J Immunol. 2005 Apr 15;174(8):4630-8.


Expression and regulation of small proline-rich protein 2 in allergic inflammation.

Zimmermann N, Doepker MP, Witte DP, Stringer KF, Fulkerson PC, Pope SM, Brandt EB, Mishra A, King NE, Nikolaidis NM, Wills-Karp M, Finkelman FD, Rothenberg ME.

Am J Respir Cell Mol Biol. 2005 May;32(5):428-35. Epub 2005 Feb 24.


Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor.

Rehli M, Sulzbacher S, Pape S, Ravasi T, Wells CA, Heinz S, Söllner L, El Chartouni C, Krause SW, Steingrimsson E, Hume DA, Andreesen R.

J Immunol. 2005 Jun 1;174(11):7111-22.


[Budesonide attenuates airway remodeling and modules the expression of Janus protein tyrosine kinase 1, and signal transducers and activators of transcription 6 in asthma: an experiment with mice].

Chen XH, Zhong NS, Zhang WD, Cao ZZ, He MZ, Luo Q, Ren XL, Li SY, L L.

Zhonghua Yi Xue Za Zhi. 2007 Jun 19;87(23):1627-32. Chinese.


A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.

Köhl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M.

J Clin Invest. 2006 Mar;116(3):783-96.


Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis.

Zimmermann N, King NE, Laporte J, Yang M, Mishra A, Pope SM, Muntel EE, Witte DP, Pegg AA, Foster PS, Hamid Q, Rothenberg ME.

J Clin Invest. 2003 Jun;111(12):1863-74.


A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.

Kheradmand F, Kiss A, Xu J, Lee SH, Kolattukudy PE, Corry DB.

J Immunol. 2002 Nov 15;169(10):5904-11.


A new mechanism regulating the initiation of allergic airway inflammation.

Kiss A, Montes M, Susarla S, Jaensson EA, Drouin SM, Wetsel RA, Yao Z, Martin R, Hamzeh N, Adelagun R, Amar S, Kheradmand F, Corry DB.

J Allergy Clin Immunol. 2007 Aug;120(2):334-42. Epub 2007 Jun 4.


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