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Items: 1 to 20 of 124

1.

Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids.

Yamada S, Funada T, Shibata N, Kobayashi M, Kawai Y, Tatsuda E, Furuhata A, Uchida K.

J Lipid Res. 2004 Apr;45(4):626-34. Epub 2004 Jan 16.

2.

Covalent binding of oxidized cholesteryl esters to protein: implications for oxidative modification of low density lipoprotein and atherosclerosis.

Kawai Y, Saito A, Shibata N, Kobayashi M, Yamada S, Osawa T, Uchida K.

J Biol Chem. 2003 Jun 6;278(23):21040-9. Epub 2003 Mar 27.

3.

Protein-bound acrolein: potential markers for oxidative stress.

Uchida K, Kanematsu M, Sakai K, Matsuda T, Hattori N, Mizuno Y, Suzuki D, Miyata T, Noguchi N, Niki E, Osawa T.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4882-7.

4.

Endogenous formation of protein adducts with carcinogenic aldehydes: implications for oxidative stress.

Ichihashi K, Osawa T, Toyokuni S, Uchida K.

J Biol Chem. 2001 Jun 29;276(26):23903-13. Epub 2001 Mar 30.

5.

Monoclonal antibody against protein-bound glutathione: use of glutathione conjugate of acrolein-modified proteins as an immunogen.

Furuhata A, Honda K, Shibata T, Chikazawa M, Kawai Y, Shibata N, Uchida K.

Chem Res Toxicol. 2012 Jul 16;25(7):1393-401. doi: 10.1021/tx300082u. Epub 2012 Jul 3.

PMID:
22716076
6.

Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateral sclerosis.

Shibata N, Yamada S, Uchida K, Hirano A, Sakoda S, Fujimura H, Sasaki S, Iwata M, Toi S, Kawaguchi M, Yamamoto T, Kobayashi M.

Brain Res. 2004 Sep 3;1019(1-2):170-7.

PMID:
15306251
7.

Detection of lipofuscin-like fluorophore in oxidized human low-density lipoprotein. 4-hydroxy-2-nonenal as a potential source of fluorescent chromophore.

Itakura K, Oya-Ito T, Osawa T, Yamada S, Toyokuni S, Shibata N, Kobayashi M, Uchida K.

FEBS Lett. 2000 May 12;473(2):249-53.

8.
9.

Lipid peroxidation of membrane phospholipids generates hydroxy-alkenals and oxidized phospholipids active in physiological and/or pathological conditions.

Catalá A.

Chem Phys Lipids. 2009 Jan;157(1):1-11. doi: 10.1016/j.chemphyslip.2008.09.004. Epub 2008 Oct 14. Review.

PMID:
18977338
10.

Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine.

Yamada S, Kumazawa S, Ishii T, Nakayama T, Itakura K, Shibata N, Kobayashi M, Sakai K, Osawa T, Uchida K.

J Lipid Res. 2001 Aug;42(8):1187-96.

11.

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

Hazell LJ, Arnold L, Flowers D, Waeg G, Malle E, Stocker R.

J Clin Invest. 1996 Mar 15;97(6):1535-44.

12.

Quantitative analysis of acrolein-specific adducts generated during lipid peroxidation-modification of proteins in vitro: identification of N(τ)-(3-propanal)histidine as the major adduct.

Maeshima T, Honda K, Chikazawa M, Shibata T, Kawai Y, Akagawa M, Uchida K.

Chem Res Toxicol. 2012 Jul 16;25(7):1384-92. doi: 10.1021/tx3000818. Epub 2012 Jul 3.

PMID:
22716039
13.

Protein modification by lipid peroxidation products: formation of malondialdehyde-derived N(epsilon)-(2-propenol)lysine in proteins.

Uchida K, Sakai K, Itakura K, Osawa T, Toyokuni S.

Arch Biochem Biophys. 1997 Oct 1;346(1):45-52.

PMID:
9328283
15.

Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis.

Uchida K, Toyokuni S, Nishikawa K, Kawakishi S, Oda H, Hiai H, Stadtman ER.

Biochemistry. 1994 Oct 18;33(41):12487-94.

PMID:
7918471
16.

Maillard reaction-like lysine modification by a lipid peroxidation product: immunochemical detection of protein-bound 2-hydroxyheptanal in vivo.

Itakura K, Furuhata A, Shibata N, Kobayashi M, Uchida K.

Biochem Biophys Res Commun. 2003 Aug 29;308(3):452-7.

PMID:
12914770
17.

Lipid peroxidation modification of protein generates Nepsilon-(4-oxononanoyl)lysine as a pro-inflammatory ligand.

Shibata T, Shimozu Y, Wakita C, Shibata N, Kobayashi M, Machida S, Kato R, Itabe H, Zhu X, Sayre LM, Uchida K.

J Biol Chem. 2011 Jun 3;286(22):19943-57. doi: 10.1074/jbc.M110.187047. Epub 2011 Apr 6.

18.

Trans-4-hydroxy-2-hexenal, a product of n-3 fatty acid peroxidation: make some room HNE...

Long EK, Picklo MJ Sr.

Free Radic Biol Med. 2010 Jul 1;49(1):1-8. doi: 10.1016/j.freeradbiomed.2010.03.015. Epub 2010 Mar 29. Review.

PMID:
20353821
19.
20.

The relation of lipid peroxidation processes with atherogenesis: a new theory on atherogenesis.

Spiteller G.

Mol Nutr Food Res. 2005 Nov;49(11):999-1013. Review.

PMID:
16270286

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