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Items: 1 to 20 of 82

1.

Chemogenomic profiling: identifying the functional interactions of small molecules in yeast.

Giaever G, Flaherty P, Kumm J, Proctor M, Nislow C, Jaramillo DF, Chu AM, Jordan MI, Arkin AP, Davis RW.

Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):793-8. Epub 2004 Jan 12.

2.

Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

PMID:
18416308
3.

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.

Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, Babu MM, Elledge SJ, Toczyski D, Lokey RS, Krogan NJ.

Mol Syst Biol. 2010 Dec 21;6:451. doi: 10.1038/msb.2010.107.

4.

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.

Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR.

Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1.

5.

Chemical genetic and chemogenomic analysis in yeast.

Coorey NV, Sampson LD, Barber JM, Bellows DS.

Methods Mol Biol. 2014;1205:169-86. doi: 10.1007/978-1-4939-1363-3_11.

PMID:
25213245
6.

Yeast on drugs: Saccharomyces cerevisiae as a tool for anticancer drug research.

Menacho-Márquez M, Murguía JR.

Clin Transl Oncol. 2007 Apr;9(4):221-8. Review.

PMID:
17462974
7.

Genome-wide analysis of the expression profile of Saccharomyces cerevisiae in response to treatment with the plant isoflavone, wighteone, as a potential antifungal agent.

Yin H, Zhao Y, Zhang Y, Zhang H, Xu L, Zou Z, Yang W, Cheng J, Zhou Y.

Biotechnol Lett. 2006 Jan;28(2):99-105.

PMID:
16369693
8.

Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae.

Agarwal AK, Rogers PD, Baerson SR, Jacob MR, Barker KS, Cleary JD, Walker LA, Nagle DG, Clark AM.

J Biol Chem. 2003 Sep 12;278(37):34998-5015. Epub 2003 Jun 24.

9.

Exploring gene function and drug action using chemogenomic dosage assays.

Ericson E, Hoon S, St Onge RP, Giaever G, Nislow C.

Methods Enzymol. 2010;470:233-55. doi: 10.1016/S0076-6879(10)70010-0. Epub 2010 Mar 1.

PMID:
20946813
10.

A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae.

Singh-Babak SD, Shekhar T, Smith AM, Giaever G, Nislow C, Cowen LE.

Mol Biosyst. 2012 Oct;8(10):2575-84. doi: 10.1039/c2mb25107h.

PMID:
22751784
11.

Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.

Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M.

BMC Microbiol. 2009 Jan 14;9:9. doi: 10.1186/1471-2180-9-9.

12.

Yeast genomics and proteomics in drug discovery and target validation.

Parsons AB, Geyer R, Hughes TR, Boone C.

Prog Cell Cycle Res. 2003;5:159-66. Review.

PMID:
14593709
13.

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.

Lum PY, Armour CD, Stepaniants SB, Cavet G, Wolf MK, Butler JS, Hinshaw JC, Garnier P, Prestwich GD, Leonardson A, Garrett-Engele P, Rush CM, Bard M, Schimmack G, Phillips JW, Roberts CJ, Shoemaker DD.

Cell. 2004 Jan 9;116(1):121-37.

14.

Functional profiling of the Saccharomyces cerevisiae genome.

Giaever G, Chu AM, Ni L, Connelly C, Riles L, Véronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Güldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kötter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M.

Nature. 2002 Jul 25;418(6896):387-91.

PMID:
12140549
15.

SKY1 and IXR1 interactions, their effects on cisplatin and spermine resistance in Saccharomyces cerevisiae.

Rodríguez Lombardero S, Vizoso Vázquez A, Rodríguez Belmonte E, González Siso MI, Cerdán ME.

Can J Microbiol. 2012 Feb;58(2):184-8. doi: 10.1139/w11-124. Epub 2012 Jan 19.

PMID:
22260231
16.

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C.

PLoS Genet. 2008 Aug 8;4(8):e1000151. doi: 10.1371/journal.pgen.1000151.

17.

Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives.

François IE, Cammue BP, Bresseleers S, Fleuren H, Hoornaert G, Mehta VP, Modha SG, Van der Eycken EV, Thevissen K.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4064-6. doi: 10.1016/j.bmcl.2009.06.024. Epub 2009 Jun 13.

PMID:
19556127
18.

Systems pharmacogenomics in yeast.

Cahan P, Marsh S, McLeod HL.

Pharmacogenomics. 2006 Mar;7(2):255-9.

PMID:
16515406
19.

Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers.

Yan Z, Costanzo M, Heisler LE, Paw J, Kaper F, Andrews BJ, Boone C, Giaever G, Nislow C.

Nat Methods. 2008 Aug;5(8):719-25. doi: 10.1038/nmeth.1231. Epub 2008 Jul 11.

PMID:
18622398
20.

Phenothiazines as potent modulators of yeast multidrug resistance.

Kolaczkowski M, Michalak K, Motohashi N.

Int J Antimicrob Agents. 2003 Sep;22(3):279-83.

PMID:
13678835

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