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Items: 1 to 20 of 174

1.

Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN.

Garl PJ, Wenzlau JM, Walker HA, Whitelock JM, Costell M, Weiser-Evans MC.

Circ Res. 2004 Feb 6;94(2):175-83. Epub 2003 Dec 1.

PMID:
14656929
2.

Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.

Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC.

Circulation. 2004 Mar 16;109(10):1299-306. Epub 2004 Mar 1.

PMID:
14993145
3.

Endothelial cell activation of the smooth muscle cell phosphoinositide 3-kinase/Akt pathway promotes differentiation.

Brown DJ, Rzucidlo EM, Merenick BL, Wagner RJ, Martin KA, Powell RJ.

J Vasc Surg. 2005 Mar;41(3):509-16.

4.

Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan.

Tran PK, Tran-Lundmark K, Soininen R, Tryggvason K, Thyberg J, Hedin U.

Circ Res. 2004 Mar 5;94(4):550-8. Epub 2004 Jan 22.

PMID:
14739157
5.

Transient reexpression of an embryonic autonomous growth phenotype by adult carotid artery smooth muscle cells after vascular injury.

Weiser-Evans MC, Quinn BE, Burkard MR, Stenmark KR.

J Cell Physiol. 2000 Jan;182(1):12-23.

PMID:
10567912
7.

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.

Razuvaev A, Henderson B, Girnita L, Larsson O, Axelson M, Hedin U, Roy J.

J Vasc Surg. 2007 Jul;46(1):108-15.

8.

Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling.

Walker HA, Whitelock JM, Garl PJ, Nemenoff RA, Stenmark KR, Weiser-Evans MC.

Mol Biol Cell. 2003 May;14(5):1941-52. Epub 2003 Jan 26.

9.

Developmental regulation of perlecan gene expression in aortic smooth muscle cells.

Weiser MC, Belknap JK, Grieshaber SS, Kinsella MG, Majack RA.

Matrix Biol. 1996 Nov;15(5):331-40.

PMID:
8981329
10.

Perlecan Heparan Sulfate Is Required for the Inhibition of Smooth Muscle Cell Proliferation by All-trans-Retinoic Acid.

Tran-Lundmark K, Tannenberg P, Rauch BH, Ekstrand J, Tran PK, Hedin U, Kinsella MG.

J Cell Physiol. 2015 Feb;230(2):482-7. doi: 10.1002/jcp.24731.

PMID:
25078760
11.

Relationship between perlecan and tropoelastin gene expression and cell replication in the developing rat pulmonary vasculature.

Belknap JK, Weiser-Evans MC, Grieshaber SS, Majack RA, Stenmark KR.

Am J Respir Cell Mol Biol. 1999 Jan;20(1):24-34.

PMID:
9870914
12.

Akt controls vascular smooth muscle cell proliferation in vitro and in vivo by delaying G1/S exit.

Stabile E, Zhou YF, Saji M, Castagna M, Shou M, Kinnaird TD, Baffour R, Ringel MD, Epstein SE, Fuchs S.

Circ Res. 2003 Nov 28;93(11):1059-65. Epub 2003 Nov 6.

PMID:
14605018
13.

CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery.

Han Y, Deng J, Guo L, Yan C, Liang M, Kang J, Liu H, Graham AM, Li S.

Cardiovasc Res. 2008 Jun 1;78(3):597-604. doi: 10.1093/cvr/cvn036. Epub 2008 Feb 11.

PMID:
18267954
14.

[FAK antisense oligodeoxynucleotides inhibit vascular smooth muscle cell migration and adhesion mediated by FAK-ERK1/2 signaling pathway].

Yin H, Wang LH, Huo Y, Peng X, Xia CF, Tang CS.

Yao Xue Xue Bao. 2002 May;37(5):334-8. Chinese.

PMID:
12579835
15.

Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation.

Yang X, Thomas DP, Zhang X, Culver BW, Alexander BM, Murdoch WJ, Rao MN, Tulis DA, Ren J, Sreejayan N.

Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20.

PMID:
16239599
16.
17.

Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival.

Ekstrand J, Razuvaev A, Folkersen L, Roy J, Hedin U.

J Vasc Surg. 2010 Jul;52(1):167-75. doi: 10.1016/j.jvs.2010.02.282.

18.

Activated focal adhesion kinase involved in adhesion and migration of vascular smooth muscle cells stimulated by fibronectin.

Yin H, Wang L, Huo Y, Peng X, Xia C, Tang C.

Chin Med J (Engl). 2002 Apr;115(4):494-7.

PMID:
12133282
19.

Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion.

Kinsella MG, Tran PK, Weiser-Evans MC, Reidy M, Majack RA, Wight TN.

Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):608-14. Epub 2003 Feb 27.

PMID:
12615671
20.

Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury.

Gotha L, Lim SY, Osherov AB, Wolff R, Qiang B, Erlich I, Nili N, Pillarisetti S, Chang YT, Tran PK, Tryggvason K, Hedin U, Tran-Lundmark K, Advani SL, Gilbert RE, Strauss BH.

Am J Physiol Heart Circ Physiol. 2014 Aug 1;307(3):H337-45. doi: 10.1152/ajpheart.00654.2013. Epub 2014 May 23.

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