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Items: 1 to 20 of 122

1.

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.

Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T, et al.

Nature. 1992 Dec 17;360(6405):689-92.

PMID:
1465135
2.

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.

Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D.

Nature. 1993 May 6;363(6424):83-5.

PMID:
8479540
3.

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.

van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.

Curr Biol. 1995 Apr 1;5(4):404-12.

4.

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases.

McGlade J, Cheng A, Pelicci G, Pelicci PG, Pawson T.

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8869-73.

5.

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D, Schlessinger J.

Cell. 1992 Aug 7;70(3):431-42.

PMID:
1322798
6.
7.

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.

Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D.

Nature. 1993 May 6;363(6424):88-92.

PMID:
8386805
8.

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation.

Ravichandran KS, Lee KK, Songyang Z, Cantley LC, Burn P, Burakoff SJ.

Science. 1993 Nov 5;262(5135):902-5.

PMID:
8235613
9.

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.

Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J.

Nature. 1993 May 6;363(6424):85-8.

PMID:
8479541
10.
12.

The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.

Skolnik EY, Lee CH, Batzer A, Vicentini LM, Zhou M, Daly R, Myers MJ Jr, Backer JM, Ullrich A, White MF, et al.

EMBO J. 1993 May;12(5):1929-36.

14.
15.

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.

Luttrell LM, Hawes BE, van Biesen T, Luttrell DK, Lansing TJ, Lefkowitz RJ.

J Biol Chem. 1996 Aug 9;271(32):19443-50.

16.

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.

Schlaepfer DD, Hanks SK, Hunter T, van der Geer P.

Nature. 1994 Dec 22-29;372(6508):786-91.

PMID:
7997267
17.

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.

Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA.

Nature. 1993 May 6;363(6424):45-51.

PMID:
8479536
19.
20.

Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins.

Salcini AE, McGlade J, Pelicci G, Nicoletti I, Pawson T, Pelicci PG.

Oncogene. 1994 Oct;9(10):2827-36.

PMID:
8084588

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