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Items: 1 to 20 of 149


Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion.

Nishita M, Wang Y, Tomizawa C, Suzuki A, Niwa R, Uemura T, Mizuno K.

J Biol Chem. 2004 Feb 20;279(8):7193-8. Epub 2003 Nov 26.


Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin.

Wang Y, Shibasaki F, Mizuno K.

J Biol Chem. 2005 Apr 1;280(13):12683-9. Epub 2005 Jan 24.


A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia.

Nagata-Ohashi K, Ohta Y, Goto K, Chiba S, Mori R, Nishita M, Ohashi K, Kousaka K, Iwamatsu A, Niwa R, Uemura T, Mizuno K.

J Cell Biol. 2004 May 24;165(4):465-71.


Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin.

Ohta Y, Kousaka K, Nagata-Ohashi K, Ohashi K, Muramoto A, Shima Y, Niwa R, Uemura T, Mizuno K.

Genes Cells. 2003 Oct;8(10):811-24.


Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation.

Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, Ohashi K, Mizuno K.

J Biol Chem. 2014 Sep 19;289(38):26302-13. doi: 10.1074/jbc.M114.565945. Epub 2014 Aug 6.


Cell cycle-associated changes in Slingshot phosphatase activity and roles in cytokinesis in animal cells.

Kaji N, Ohashi K, Shuin M, Niwa R, Uemura T, Mizuno K.

J Biol Chem. 2003 Aug 29;278(35):33450-5. Epub 2003 Jun 14.


Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis.

Jovceva E, Larsen MR, Waterfield MD, Baum B, Timms JF.

J Cell Sci. 2007 Jun 1;120(Pt 11):1888-97. Epub 2007 May 15.


Molecular dissection of the mechanisms of substrate recognition and F-actin-mediated activation of cofilin-phosphatase Slingshot-1.

Kurita S, Watanabe Y, Gunji E, Ohashi K, Mizuno K.

J Biol Chem. 2008 Nov 21;283(47):32542-52. doi: 10.1074/jbc.M804627200. Epub 2008 Sep 22.


Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot.

Eiseler T, Döppler H, Yan IK, Kitatani K, Mizuno K, Storz P.

Nat Cell Biol. 2009 May;11(5):545-56. doi: 10.1038/ncb1861. Epub 2009 Mar 29.


Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

Soosairajah J, Maiti S, Wiggan O, Sarmiere P, Moussi N, Sarcevic B, Sampath R, Bamburg JR, Bernard O.

EMBO J. 2005 Feb 9;24(3):473-86. Epub 2005 Jan 20.


Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration.

Nishita M, Tomizawa C, Yamamoto M, Horita Y, Ohashi K, Mizuno K.

J Cell Biol. 2005 Oct 24;171(2):349-59. Epub 2005 Oct 17.


Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells.

San Martín A, Lee MY, Williams HC, Mizuno K, Lassègue B, Griendling KK.

Circ Res. 2008 Feb 29;102(4):432-8. Epub 2007 Dec 20.


Regulation of cofilin activity by CaMKII and calcineurin.

Zhao JW, Gao ZL, Ji QY, Wang H, Zhang HY, Yang YD, Xing FJ, Meng LJ, Wang Y.

Am J Med Sci. 2012 Dec;344(6):462-72. doi: 10.1097/MAJ.0b013e318244745b.


Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

Niwa R, Nagata-Ohashi K, Takeichi M, Mizuno K, Uemura T.

Cell. 2002 Jan 25;108(2):233-46.


Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.

Endo M, Ohashi K, Sasaki Y, Goshima Y, Niwa R, Uemura T, Mizuno K.

J Neurosci. 2003 Apr 1;23(7):2527-37.


Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

Lizcano JM, Alrubaie S, Kieloch A, Deak M, Leevers SJ, Alessi DR.

Biochem J. 2003 Sep 1;374(Pt 2):297-306.


Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin.

Vitolo MI, Boggs AE, Whipple RA, Yoon JR, Thompson K, Matrone MA, Cho EH, Balzer EM, Martin SS.

Oncogene. 2013 Apr 25;32(17):2200-10. doi: 10.1038/onc.2012.234. Epub 2012 Jun 11.


PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.

Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.

J Biol Chem. 2005 Jun 10;280(23):22523-9. Epub 2005 Apr 11.


Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension.

Meberg PJ, Ono S, Minamide LS, Takahashi M, Bamburg JR.

Cell Motil Cytoskeleton. 1998;39(2):172-90.


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