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Items: 1 to 20 of 144


Akt activation in platelets depends on Gi signaling pathways.

Kim S, Jin J, Kunapuli SP.

J Biol Chem. 2004 Feb 6;279(6):4186-95. Epub 2003 Nov 17.


Protease-activated receptor-induced Akt activation--regulation and possible function.

Reséndiz JC, Kroll MH, Lassila R.

J Thromb Haemost. 2007 Dec;5(12):2484-93. Epub 2007 Sep 19.


Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.

Shankar H, Murugappan S, Kim S, Jin J, Ding Z, Wickman K, Kunapuli SP.

Blood. 2004 Sep 1;104(5):1335-43. Epub 2004 May 13.


Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.

Garcia A, Kim S, Bhavaraju K, Schoenwaelder SM, Kunapuli SP.

Biochem J. 2010 Jul 15;429(2):369-77. doi: 10.1042/BJ20100166.


Identification of P2Y12-dependent and -independent mechanisms of glycoprotein VI-mediated Rap1 activation in platelets.

Larson MK, Chen H, Kahn ML, Taylor AM, Fabre JE, Mortensen RM, Conley PB, Parise LV.

Blood. 2003 Feb 15;101(4):1409-15. Epub 2002 Oct 17.


The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.

Grenegård M, Vretenbrant-Oberg K, Nylander M, Désilets S, Lindström EG, Larsson A, Ramström I, Ramström S, Lindahl TL.

J Biol Chem. 2008 Jul 4;283(27):18493-504. doi: 10.1074/jbc.M800358200. Epub 2008 May 14.


Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.

Roger S, Pawlowski M, Habib A, Jandrot-Perrus M, Rosa JP, Bryckaert M.

FEBS Lett. 2004 Jan 2;556(1-3):227-35.


Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets.

Nieswandt B, Schulte V, Zywietz A, Gratacap MP, Offermanns S.

J Biol Chem. 2002 Oct 18;277(42):39493-8. Epub 2002 Aug 14.


Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.

Lova P, Campus F, Lombardi R, Cattaneo M, Sinigaglia F, Balduini C, Torti M.

J Biol Chem. 2004 Jun 11;279(24):25299-306. Epub 2004 Apr 12.


Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets.

Dorsam RT, Kim S, Jin J, Kunapuli SP.

J Biol Chem. 2002 Dec 6;277(49):47588-95. Epub 2002 Sep 23.


Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets?

Kahner BN, Quinton TM, Langan S, Kunapuli SP.

Platelets. 2006 Sep;17(6):397-404.


A differential role of the platelet ADP receptors P2Y1 and P2Y12 in Rac activation.

Soulet C, Hechler B, Gratacap MP, Plantavid M, Offermanns S, Gachet C, Payrastre B.

J Thromb Haemost. 2005 Oct;3(10):2296-306.


Gi-dependent and -independent mechanisms downstream of the P2Y12 ADP-receptor.

Soulet C, Sauzeau V, Plantavid M, Herbert JM, Pacaud P, Payrastre B, Savi P.

J Thromb Haemost. 2004 Jan;2(1):135-46. Erratum in: J Thromb Haemost. 2004 Jun;2(6):1027.

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