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14599847,14599851,14599846,15383571,15634886,20359955,12847240,16585551,14568933,15356107,15039384,17681173,10843721,12937416,17161341,12949259,31781669,8093606,12193715,14530324,14734610,16122720,8920883,17428252,19155973,11120794,22250081,30863412,10925277,11535631,14609225,15070759,19715524,11441119,21718313,16804081,7485382,15758078,15340148,10480600,11298351,15616013,12406908,12645949,14676299,15843527,11994458,16236126,12221281,10535448,14645158,16784487,11591746,9933451,29503651,17676307,9376074,15383562,9867218,16505040,12055228,15343360,14734611,12390307,15039392,20625402,12887099,16951329,18941193,26797873,21458378,20843956,16790365,17785799,22063316,11564833,20956337,17182553,16301639,26208605,17541623,14607897,14768049,17490400,15184500,16918694,11714835,16126946,34526376,26283479,30122420,15237111,12750357,9885918,14515264,15557171,19050244,17114433,18981116,12682229,14707053,17307871,10677243,17307796,32111734,16456026,21175595,18815284,31358881,18465768,17114428,15731180,10553041,14634104,19448155,19824917,21357258,19336675,31039339,20545784,18075857,15374887,17438084,19188681,20331474,14609223,19946662,25187361,12438424,16000960,15713793,18453575,21711461,18686627,22865049,21745722,27745778,17374136,30022165,19208751,14609212,10553098,22789848,18226498,21717080,31806623,24943217,22647732,33262765,29546475,19833887,14599845,24499272,24737163,24601987,29594371,15753206,19208910,19011680,19008314,30908554,9670041,27920091,20033667,18266851,31109955,23293979,15485628,23685789,24628444,15016653,23925934,19421731,27920090,18334954,23894591,20660617,14519757,17920698,11390436,22733744,29950508,16731819,25302633,19176319,24204793,32295876,18460018,22043012,14599849,22718263,21469125,23119065,12034883,15090447,19752238,18608174,23405091,20695767,19644014,29712852,18469093,23834659,30952805,30634133,18308639,17062002,23524573,23648548,19770362,26590312,26019217,15271794,31836691,18430797,19050249,31473255,19884905,20703438,19016910,26608914,18390700,33208230,23626013,24984576,30916998,22728763,10449528,25393309,19122373,12506037,22745325,18490731,19936238,12855551,21765853,21220322,19171501,18316361,18560422,23699989,18626021,16403912,20162554,20584884,35140133,31127035,22579473,24196968,17130491,9122227,31254568,28874533,14678036,22751694,12543858,19342642,19291704,20190756,24043895,21169553,15707399,20544263,18765477,20855871,35007324,19666526,30761151,19571798,23663075,34954557,16670772,33343569,21542943,21220309,15479730,19783679,22043003,21469083,16805788,31586630,21683079,23195956,19689732,23729499,22447930,18492787,29955175,19223596,31419705,34527002,16621963,19924236,22606220,21124839,22403296,24089508,33822842,24550292,33151102,28611473,30454875,20368276,12775574,15837814,18543112,9864219,34113344,21949373,18390698,18039815,23685786,23844100,16224273,20483737,29976617,34163475,30651340,34779254,32335144,32058174,23716674,15728475,31486854,35725270,20080388,19180473,18349126,23804274,24943731,35123388,8724893,23039884,19703010,19478458,22069258,16263787,31723081,23406759,15105293,24446517,32787283,24658435,17878385,34320351,26791362,17024440,16179369,34207474,20490452,24556398,15473695,22400033,17983440,20980458,24472603,16621991,32508814,11493476,30681867,19120288,19203099,23894487,34026440,19690518,32615414,16790855,24812429,14599852,20641385,32661685,20308362,20225396,24676641,33295943,22891339,21251614,23895744,15528313,12752307,19037920,19286348,30518692,21914624,19052741,21690251,31852918,33734705,21647403,16622000,19439734,10618410,20864513,24853397,22649557,19752032,19654878,31131864,33291571,25880134,30051618,34497137,18689692,33995402,25759840,21825122,20453445,15067033,23396943,22698916,22933401,15684039,30514969,24918037,19203097,22484814,23447122,15699486,32250253,32256194,25267644,25213337,30777937,14757740,25198526,18641317,20534455,29255035,21647405,31274300,23956420,9012359,34643294,31444529,22065673,15637139,16214084,15571925,21734016,16628253,21289272,20547977,26173023,32492367,20139986,19321585,36339431,12893754,21470634,19017948,24465383,24466007,24123682,22871665,34665600,31728048,16982871,31575864,33986758,24696448,31260253,24551182,15899580,19204074,15725955,15996259,21559409,18701887,30940840,16418326,35878027,16169501,33479911,14720578,10397255,32483133,36032090,32843568,27502276,24943216,22393537,33139567,34620616,18795974,23490422,35145521,20060833,24728138,32306719,20566717,16332974,20601599,31423480,35311607,19172487,18299579,35444659,7591058,24127484,17711492,34129722,6227072,17018858,36275764,31475985,19822646,32438694,31821046,32209472,35406645,20180832,23532986,22277969,31371518,18523243,22733018,23198878,22709273,25243429,21788572,23226641,23804269,21209873,22362174,20601600,21307076,22615750,19561321,19052699,25189436,26829986,25918233,23650440,24239002,26783747,16237074,26085090,36719009,24714634,9465083,18060022,36032077,21768354,16688844,27882092,24335706,29426942,19530995,30648196,19203092,24166280,19203100,24415782,30343099,18028371,22025302,15890793,20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CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

Mukherjee R, Chaturvedi P, Qin HY, Singh B. Mukherjee R, et al. J Autoimmun. 2003 Nov;21(3):221-37. doi: 10.1016/s0896-8411(03)00114-8. J Autoimmun. 2003. PMID: 14599847

Role of ICAM-1 and P-selectin expression in the development and effector function of CD4+CD25+regulatory T cells.

Kohm AP, Miller SD. Kohm AP, et al. J Autoimmun. 2003 Nov;21(3):261-71. doi: 10.1016/s0896-8411(03)00117-3. J Autoimmun. 2003. PMID: 14599851

Nondepleting anti-CD4 monoclonal antibody prevents diabetes and blocks induction of insulin autoantibodies following insulin peptide B:9-23 immunization in the NOD mouse.

Liu E, Moriyama H, Paronen J, Abiru N, Miao D, Yu L, Taylor RM, Eisenbarth GS. Liu E, et al. J Autoimmun. 2003 Nov;21(3):213-9. doi: 10.1016/s0896-8411(03)00116-1. J Autoimmun. 2003. PMID: 14599846

Perturbed homeostasis of peripheral T cells elicits decreased susceptibility to anti-CD3-induced apoptosis in prediabetic nonobese diabetic mice.

Yang W, Hussain S, Mi QS, Santamaria P, Delovitch TL. Yang W, et al. J Immunol. 2004 Oct 1;173(7):4407-16. doi: 10.4049/jimmunol.173.7.4407. J Immunol. 2004. PMID: 15383571

Dysregulated B7-1 and B7-2 expression on nonobese diabetic mouse B cells is associated with increased T cell costimulation and the development of insulitis.

Hussain S, Delovitch TL. Hussain S, et al. J Immunol. 2005 Jan 15;174(2):680-7. doi: 10.4049/jimmunol.174.2.680. J Immunol. 2005. PMID: 15634886

Administration of a determinant of preproinsulin can induce regulatory T cells and suppress anti-islet autoimmunity in NOD mice.

Arai T, Moriyama H, Shimizu M, Sasaki H, Kishi M, Okumachi Y, Yasuda H, Hara K, Yokono K, Nagata M. Arai T, et al. Clin Immunol. 2010 Jul;136(1):74-82. doi: 10.1016/j.clim.2010.02.016. Epub 2010 Apr 1. Clin Immunol. 2010. PMID: 20359955

Induction of autoantigen-specific Th2 and Tr1 regulatory T cells and modulation of autoimmune diabetes.

Chen C, Lee WH, Yun P, Snow P, Liu CP. Chen C, et al. J Immunol. 2003 Jul 15;171(2):733-44. doi: 10.4049/jimmunol.171.2.733. J Immunol. 2003. PMID: 12847240

Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes.

Every AL, Kramer DR, Mannering SI, Lew AM, Harrison LC. Every AL, et al. J Immunol. 2006 Apr 15;176(8):4608-15. doi: 10.4049/jimmunol.176.8.4608. J Immunol. 2006. PMID: 16585551

Early events in peripheral regulatory T cell induction via the nasal mucosa.

Unger WW, Hauet-Broere F, Jansen W, van Berkel LA, Kraal G, Samsom JN. Unger WW, et al. J Immunol. 2003 Nov 1;171(9):4592-603. doi: 10.4049/jimmunol.171.9.4592. J Immunol. 2003. PMID: 14568933

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets.

Yadav D, Judkowski V, Flodstrom-Tullberg M, Sterling L, Redmond WL, Sherman L, Sarvetnick N. Yadav D, et al. J Immunol. 2004 Sep 15;173(6):3631-9. doi: 10.4049/jimmunol.173.6.3631. J Immunol. 2004. PMID: 15356107

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