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Items: 1 to 20 of 74

1.

SEPT5_v2 is a parkin-binding protein.

Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B.

Brain Res Mol Brain Res. 2003 Oct 7;117(2):179-89.

PMID:
14559152
2.

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI.

Huynh DP, Scoles DR, Nguyen D, Pulst SM.

Hum Mol Genet. 2003 Oct 15;12(20):2587-97. Epub 2003 Aug 12.

PMID:
12925569
3.

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.

Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM.

Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13354-9.

4.

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.

Lim KL, Chew KC, Tan JM, Wang C, Chung KK, Zhang Y, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM.

J Neurosci. 2005 Feb 23;25(8):2002-9.

5.

Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein.

Kemeny S, Dery D, Loboda Y, Rovner M, Lev T, Zuri D, Finberg JP, Larisch S.

PLoS One. 2012;7(7):e38837. doi: 10.1371/journal.pone.0038837. Epub 2012 Jul 9.

6.

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.

Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ.

Science. 2001 Jul 13;293(5528):263-9. Epub 2001 Jun 28.

7.

Parkin ubiquitinates and promotes the degradation of RanBP2.

Um JW, Min DS, Rhim H, Kim J, Paik SR, Chung KC.

J Biol Chem. 2006 Feb 10;281(6):3595-603. Epub 2005 Dec 6.

8.

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity.

Hampe C, Ardila-Osorio H, Fournier M, Brice A, Corti O.

Hum Mol Genet. 2006 Jul 1;15(13):2059-75. Epub 2006 May 19.

PMID:
16714300
9.

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

Tsai YC, Fishman PS, Thakor NV, Oyler GA.

J Biol Chem. 2003 Jun 13;278(24):22044-55. Epub 2003 Apr 3.

10.

Parkin is metabolized by the ubiquitin/proteosome system.

Choi P, Ostrerova-Golts N, Sparkman D, Cochran E, Lee JM, Wolozin B.

Neuroreport. 2000 Aug 21;11(12):2635-8.

PMID:
10976934
11.

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.

Trempe JF, Chen CX, Grenier K, Camacho EM, Kozlov G, McPherson PS, Gehring K, Fon EA.

Mol Cell. 2009 Dec 25;36(6):1034-47. doi: 10.1016/j.molcel.2009.11.021.

12.

Drosophila melanogaster Parkin ubiquitinates peanut and septin1 as an E3 ubiquitin-protein ligase.

Bae YJ, Kang SJ, Park KS.

Insect Biochem Mol Biol. 2007 May;37(5):430-9. Epub 2007 Feb 12.

PMID:
17456438
13.

Parkin mediates the degradation-independent ubiquitination of Hsp70.

Moore DJ, West AB, Dikeman DA, Dawson VL, Dawson TM.

J Neurochem. 2008 Jun;105(5):1806-19. doi: 10.1111/j.1471-4159.2008.05261.x. Epub 2008 Feb 1.

14.

Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.

Lim MK, Kawamura T, Ohsawa Y, Ohtsubo M, Asakawa S, Takayanagi A, Shimizu N.

Exp Cell Res. 2007 Aug 1;313(13):2858-74. Epub 2007 Apr 20.

PMID:
17512523
15.

RING finger ubiquitin-protein isopeptide ligase Nrdp1/FLRF regulates parkin stability and activity.

Zhong L, Tan Y, Zhou A, Yu Q, Zhou J.

J Biol Chem. 2005 Mar 11;280(10):9425-30. Epub 2005 Jan 4.

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18.

Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis.

Amin ND, Zheng YL, Kesavapany S, Kanungo J, Guszczynski T, Sihag RK, Rudrabhatla P, Albers W, Grant P, Pant HC.

J Neurosci. 2008 Apr 2;28(14):3631-43. doi: 10.1523/JNEUROSCI.0453-08.2008.

19.

Parkin and defective ubiquitination in Parkinson's disease.

Dawson TM.

J Neural Transm Suppl. 2006;(70):209-13. Review.

PMID:
17017531
20.

Co-association of parkin and alpha-synuclein.

Choi P, Golts N, Snyder H, Chong M, Petrucelli L, Hardy J, Sparkman D, Cochran E, Lee JM, Wolozin B.

Neuroreport. 2001 Sep 17;12(13):2839-43.

PMID:
11588587

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