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Items: 1 to 20 of 73

1.

Gene expression profiling in Werner syndrome closely resembles that of normal aging.

Kyng KJ, May A, Kølvraa S, Bohr VA.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12259-64. Epub 2003 Oct 3.

2.

Transcripts of aging.

Vijg J, Calder RB.

Trends Genet. 2004 Jun;20(6):221-4. Review. Erratum in: Trends Genet. 2005 Jan;21(1):36.

PMID:
15145572
3.

Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.

Kyng KJ, May A, Stevnsner T, Becker KG, Kølvrå S, Bohr VA.

Oncogene. 2005 Jul 28;24(32):5026-42.

PMID:
15897889
4.
5.

Werner syndrome and biological ageing: a molecular genetic hypothesis.

Thweatt R, Goldstein S.

Bioessays. 1993 Jun;15(6):421-6. Review.

PMID:
8357345
6.
7.

DNA repair fine structure in Werner's syndrome cell lines.

Webb DK, Evans MK, Bohr VA.

Exp Cell Res. 1996 May 1;224(2):272-8.

PMID:
8612704
8.

Investigation of the signaling pathways involved in the proliferative life span barriers in werner syndrome fibroblasts.

Davis T, Faragher RG, Jones CJ, Kipling D.

Ann N Y Acad Sci. 2004 Jun;1019:274-7.

PMID:
15247028
9.

Gene expression and DNA repair in progeroid syndromes and human aging.

Kyng KJ, Bohr VA.

Ageing Res Rev. 2005 Nov;4(4):579-602. Epub 2005 Oct 24. Review.

PMID:
16246641
10.
11.

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.

Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, Kipling D.

J Cell Sci. 2003 Apr 1;116(Pt 7):1349-57.

12.

No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.

de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, Toussaint O.

Ann N Y Acad Sci. 2004 Jun;1019:375-8. Review.

PMID:
15247048
13.

Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.

Murano S, Thweatt R, Shmookler Reis RJ, Jones RA, Moerman EJ, Goldstein S.

Mol Cell Biol. 1991 Aug;11(8):3905-14.

14.

Analysis of microsatellite instability and hypermutation of immunoglobulin variable genes in Werner syndrome.

Rosner K, Winter DB, Skovgaard GL, Oshima J, Gearhart PJ, Bohr VA.

Mech Ageing Dev. 2001 Aug;122(11):1121-33.

PMID:
11389928
15.

Studies on the molecular-genetic basis of replicative senescence in Werner syndrome and normal fibroblasts.

Goldstein S, Murano S, Benes H, Moerman EJ, Jones RA, Thweatt R, Shmookler Reis RJ, Howard BH.

Exp Gerontol. 1989;24(5-6):461-8.

PMID:
2632280
16.

The gene responsible for Werner syndrome may be a cell division "counting" gene.

Faragher RG, Kill IR, Hunter JA, Pope FM, Tannock C, Shall S.

Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):12030-4.

17.

Unexpectedly low loss of heterozygosity in genetically unstable Werner syndrome cell lines.

Brooks-Wilson AR, Emond MJ, Monnat RJ Jr.

Genes Chromosomes Cancer. 1997 Feb;18(2):133-42.

PMID:
9115963
19.

Increased chromosome instability and accumulation of DNA double-strand breaks in Werner syndrome cells.

Ariyoshi K, Suzuki K, Goto M, Watanabe M, Kodama S.

J Radiat Res. 2007 May;48(3):219-31. Epub 2007 Apr 23.

20.

Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.

Baird DM, Davis T, Rowson J, Jones CJ, Kipling D.

Hum Mol Genet. 2004 Jul 15;13(14):1515-24. Epub 2004 May 18.

PMID:
15150162

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