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Items: 1 to 20 of 140


A functional genomic analysis of cell morphology using RNA interference.

Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N.

J Biol. 2003;2(4):27. Epub 2003 Oct 1.


Cellular phenotype recognition for high-content RNA interference genome-wide screening.

Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST.

J Biomol Screen. 2008 Jan;13(1):29-39. doi: 10.1177/1087057107311223.


RNA interference of gene expression (RNAi) in cultured Drosophila cells.

Worby CA, Simonson-Leff N, Dixon JE.

Sci STKE. 2001 Aug 14;2001(95):pl1.


Prevalence of off-target effects in Drosophila RNA interference screens.

Ma Y, Creanga A, Lum L, Beachy PA.

Nature. 2006 Sep 21;443(7109):359-63. Epub 2006 Sep 10.


Genome-wide RNAi analysis of growth and viability in Drosophila cells.

Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Paro R, Perrimon N; Heidelberg Fly Array Consortium.

Science. 2004 Feb 6;303(5659):832-5.


Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

Bai SW, Herrera-Abreu MT, Rohn JL, Racine V, Tajadura V, Suryavanshi N, Bechtel S, Wiemann S, Baum B, Ridley AJ.

BMC Biol. 2011 Aug 11;9:54. doi: 10.1186/1741-7007-9-54.


A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.

DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N.

Genome Biol. 2007;8(9):R203.


RNA interference screen to identify genes required for Drosophila embryonic nervous system development.

Koizumi K, Higashida H, Yoo S, Islam MS, Ivanov AI, Guo V, Pozzi P, Yu SH, Rovescalli AC, Tang D, Nirenberg M.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5626-31. Epub 2007 Mar 21.


Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype.

Rohn JL, Sims D, Liu T, Fedorova M, Schöck F, Dopie J, Vartiainen MK, Kiger AA, Perrimon N, Baum B.

J Cell Biol. 2011 Sep 5;194(5):789-805. doi: 10.1083/jcb.201103168.


Off-target effects associated with long dsRNAs in Drosophila RNAi screens.

Moffat J, Reiling JH, Sabatini DM.

Trends Pharmacol Sci. 2007 Apr;28(4):149-51. Epub 2007 Mar 9.


Evidence of a tick RNAi pathway by comparative genomics and reverse genetics screen of targets with known loss-of-function phenotypes in Drosophila.

Kurscheid S, Lew-Tabor AE, Rodriguez Valle M, Bruyeres AG, Doogan VJ, Munderloh UG, Guerrero FD, Barrero RA, Bellgard MI.

BMC Mol Biol. 2009 Mar 26;10:26. doi: 10.1186/1471-2199-10-26.


Inducing RNAi in Drosophila cells by soaking with dsRNA.

Zhou R, Mohr S, Hannon GJ, Perrimon N.

Cold Spring Harb Protoc. 2014 May 1;2014(5). pii: pdb.prot080747. doi: 10.1101/pdb.prot080747.


The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing.

Saleh MC, van Rij RP, Hekele A, Gillis A, Foley E, O'Farrell PH, Andino R.

Nat Cell Biol. 2006 Aug;8(8):793-802. Epub 2006 Jul 23.


Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA.

Science. 2003 Mar 28;299(5615):2039-45.


Functional genomic analysis of the Wnt-wingless signaling pathway.

DasGupta R, Kaykas A, Moon RT, Perrimon N.

Science. 2005 May 6;308(5723):826-33. Epub 2005 Apr 7.


A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis.

D'Ambrosio MV, Vale RD.

J Cell Biol. 2010 Nov 1;191(3):471-8. doi: 10.1083/jcb.201003135.


A targeted UAS-RNAi screen in Drosophila larvae identifies wound closure genes regulating distinct cellular processes.

Lesch C, Jo J, Wu Y, Fish GS, Galko MJ.

Genetics. 2010 Nov;186(3):943-57. doi: 10.1534/genetics.110.121822. Epub 2010 Sep 2.


Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.

Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST.

BMC Bioinformatics. 2008 Jun 5;9:264. doi: 10.1186/1471-2105-9-264.

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