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Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth.

Hornberger TA, McLoughlin TJ, Leszczynski JK, Armstrong DD, Jameson RR, Bowen PE, Hwang ES, Hou H, Moustafa ME, Carlson BA, Hatfield DL, Diamond AM, Esser KA.

J Nutr. 2003 Oct;133(10):3091-7.


Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function.

Carlson BA, Novoselov SV, Kumaraswamy E, Lee BJ, Anver MR, Gladyshev VN, Hatfield DL.

J Biol Chem. 2004 Feb 27;279(9):8011-7. Epub 2003 Dec 4.


Selective rescue of selenoprotein expression in mice lacking a highly specialized methyl group in selenocysteine tRNA.

Carlson BA, Xu XM, Gladyshev VN, Hatfield DL.

J Biol Chem. 2005 Feb 18;280(7):5542-8. Epub 2004 Dec 17.


Maximal lengthening contractions increase p70 S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply.

Eliasson J, Elfegoun T, Nilsson J, Köhnke R, Ekblom B, Blomstrand E.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1197-205. Epub 2006 Jul 11.


Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.

Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR.

J Biol Chem. 2005 Jan 21;280(3):1838-48. Epub 2004 Nov 1.


Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

Anthony TG, McDaniel BJ, Byerley RL, McGrath BC, Cavener DR, McNurlan MA, Wek RC.

J Biol Chem. 2004 Aug 27;279(35):36553-61. Epub 2004 Jun 22.


Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism.

Hornberger TA, Stuppard R, Conley KE, Fedele MJ, Fiorotto ML, Chin ER, Esser KA.

Biochem J. 2004 Jun 15;380(Pt 3):795-804.


A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo.

Shavlakadze T, Chai J, Maley K, Cozens G, Grounds G, Winn N, Rosenthal N, Grounds MD.

J Cell Sci. 2010 Mar 15;123(Pt 6):960-71. doi: 10.1242/jcs.061119. Epub 2010 Feb 23. Erratum in: J Cell Sci. 2013 Oct 1;126(Pt 19):4536.


Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury.

Boppart MD, Burkin DJ, Kaufman SJ.

Am J Physiol Cell Physiol. 2006 Jun;290(6):C1660-5. Epub 2006 Jan 18.


Changes in signalling pathways regulating protein synthesis in human muscle in the recovery period after endurance exercise.

Mascher H, Andersson H, Nilsson PA, Ekblom B, Blomstrand E.

Acta Physiol (Oxf). 2007 Sep;191(1):67-75. Epub 2007 May 3.


Refeeding and insulin activate the AKT/p70S6 kinase pathway without affecting IRS1 tyrosine phosphorylation in chicken muscle.

Duchêne S, Métayer S, Audouin E, Bigot K, Dupont J, Tesseraud S.

Domest Anim Endocrinol. 2008 Jan;34(1):1-13. Epub 2006 Sep 25.


Selenocysteine tRNA[Ser]Sec levels and selenium-dependent glutathione peroxidase activity in mouse embryonic stem cells heterozygous for a targeted mutation in the tRNA[Ser]Sec gene.

Chittum HS, Baek HJ, Diamond AM, Fernandez-Salguero P, Gonzalez F, Ohama T, Hatfield DL, Kuehn M, Lee BJ.

Biochemistry. 1997 Jul 15;36(28):8634-9.


Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.

Wu Q, Kiguchi K, Kawamoto T, Ajiki T, Traag J, Carbajal S, Ruffino L, Thames H, Wistuba I, Thomas M, Vasquez KM, DiGiovanni J.

Cancer Res. 2007 Apr 15;67(8):3794-800.


Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice.

DiPasquale DM, Cheng M, Billich W, Huang SA, van Rooijen N, Hornberger TA, Koh TJ.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1278-85. Epub 2007 Jul 25.


Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch.

Bradley JM, Kelley MJ, Rose A, Acott TS.

Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5174-81.


Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.

Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.

Cancer Res. 2005 Nov 1;65(21):9953-61.


Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.

Kemi OJ, Ceci M, Wisloff U, Grimaldi S, Gallo P, Smith GL, Condorelli G, Ellingsen O.

J Cell Physiol. 2008 Feb;214(2):316-21.


Recovery of skeletal muscle mass after extensive injury: positive effects of increased contractile activity.

Richard-Bulteau H, Serrurier B, Crassous B, Banzet S, Peinnequin A, Bigard X, Koulmann N.

Am J Physiol Cell Physiol. 2008 Feb;294(2):C467-76. Epub 2007 Dec 12.

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