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Items: 1 to 20 of 117

1.

The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism.

Ferlin A, Simonato M, Bartoloni L, Rizzo G, Bettella A, Dottorini T, Dallapiccola B, Foresta C.

J Clin Endocrinol Metab. 2003 Sep;88(9):4273-9.

PMID:
12970298
2.

Role of INSL3 and LGR8 in cryptorchidism and testicular functions.

Foresta C, Ferlin A.

Reprod Biomed Online. 2004 Sep;9(3):294-8.

PMID:
15353080
3.

Lack of LGR8 gene mutation in Finnish patients with a family history of cryptorchidism.

Roh J, Virtanen H, Kumagai J, Sudo S, Kaleva M, Toppari J, Hsueh AJ.

Reprod Biomed Online. 2003 Oct-Nov;7(4):400-6.

PMID:
14656401
4.

Insulin-like factor 3 gene mutations in testicular dysgenesis syndrome: clinical and functional characterization.

Ferlin A, Bogatcheva NV, Gianesello L, Pepe A, Vinanzi C, Agoulnik AI, Foresta C.

Mol Hum Reprod. 2006 Jun;12(6):401-6. Epub 2006 May 10.

PMID:
16687567
5.

Mutation and polymorphism analyses of INSL3 and LGR8/GREAT in 62 Japanese patients with cryptorchidism.

Yamazawa K, Wada Y, Sasagawa I, Aoki K, Ueoka K, Ogata T.

Horm Res. 2007;67(2):73-6. Epub 2006 Oct 6.

PMID:
17028442
6.

GREAT/LGR8 is the only receptor for insulin-like 3 peptide.

Bogatcheva NV, Truong A, Feng S, Engel W, Adham IM, Agoulnik AI.

Mol Endocrinol. 2003 Dec;17(12):2639-46. Epub 2003 Aug 21.

PMID:
12933905
7.

INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent.

Kumagai J, Hsu SY, Matsumi H, Roh JS, Fu P, Wade JD, Bathgate RA, Hsueh AJ.

J Biol Chem. 2002 Aug 30;277(35):31283-6. Epub 2002 Jul 11.

8.

Different insulin-like 3 (INSL3) gene mutations not associated with human cryptorchidism.

Marin P, Ferlin A, Moro E, Garolla A, Foresta C.

J Endocrinol Invest. 2001 Apr;24(4):RC13-5.

PMID:
11383919
9.

INSL3/LGR8 role in testicular descent and cryptorchidism.

Bogatcheva NV, Agoulnik AI.

Reprod Biomed Online. 2005 Jan;10(1):49-54. Review.

PMID:
15705294
10.

No association between T222P/LGR8 mutation and cryptorchidism in the Moroccan population.

El Houate B, Rouba H, Imken L, Sibai H, Chafik A, Boulouiz R, Chadli E, Hassar M, McElreavey K, Barakat A.

Horm Res. 2008;70(4):236-9. doi: 10.1159/000151596. Epub 2008 Sep 5.

PMID:
18772597
11.

Mutation analysis of INSL3 and GREAT/LGR8 genes in familial cryptorchidism.

Feng S, Cortessis VK, Hwang A, Hardy B, Koh CJ, Bogatcheva NV, Agoulnik AI.

Urology. 2004 Nov;64(5):1032-6.

PMID:
15533513
12.

Prenatal exposure to diaethylstilbestrol in the rat inhibits transabdominal testicular descent with involvement of the INSL3/LGR8 system and HOXA10.

Zhang L, Zheng XM, Hubert J, Zheng H, Yang ZW, Li SW.

Chin Med J (Engl). 2009 Apr 20;122(8):967-71.

PMID:
19493424
13.

T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane.

Bogatcheva NV, Ferlin A, Feng S, Truong A, Gianesello L, Foresta C, Agoulnik AI.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E138-44. Epub 2006 Aug 22.

PMID:
16926383
14.

Novel mutations involving the INSL3 gene associated with cryptorchidism.

El Houate B, Rouba H, Sibai H, Barakat A, Chafik A, Chadli el B, Imken L, Bogatcheva NV, Feng S, Agoulnik AI, McElreavey K.

J Urol. 2007 May;177(5):1947-51.

PMID:
17437853
15.

Mutations in INSL3 and RXFP2 genes in cryptorchid boys.

Ferlin A, Zuccarello D, Garolla A, Selice R, Vinanzi C, Ganz F, Zanon GF, Zuccarello B, Foresta C.

Ann N Y Acad Sci. 2009 Apr;1160:213-4. doi: 10.1111/j.1749-6632.2008.03784.x.

PMID:
19416190
16.

Paracrine and endocrine roles of insulin-like factor 3.

Ferlin A, Arredi B, Zuccarello D, Garolla A, Selice R, Foresta C.

J Endocrinol Invest. 2006 Jul-Aug;29(7):657-64. Review.

PMID:
16957417
17.

The molecular basis of cryptorchidism.

Ivell R, Hartung S.

Mol Hum Reprod. 2003 Apr;9(4):175-81. Review.

PMID:
12651898
18.

Environmental effects on hormonal regulation of testicular descent.

Toppari J, Virtanen H, Skakkebaek NE, Main KM.

J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):184-6. Epub 2006 Oct 17. Review.

PMID:
17049842
19.

Cryptorchidism in mice mutant for Insl3.

Nef S, Parada LF.

Nat Genet. 1999 Jul;22(3):295-9.

PMID:
10391220
20.

Genetic targeting of relaxin and insl3 signaling in mice.

Feng S, Bogatcheva NV, Kamat AA, Agoulnik AI.

Ann N Y Acad Sci. 2005 May;1041:82-90.

PMID:
15956690

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