Similar articles for PMID: 12963974

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1

A MEK inhibitor (U0126) prolongs survival in nude mice bearing human gallbladder cancer cells with K-ras mutation: analysis in a novel orthotopic inoculation model.

Horiuchi H, Kawamata H, Fujimori T, Kuroda Y. Horiuchi H, et al. Int J Oncol. 2003 Oct;23(4):957-63. Int J Oncol. 2003. PMID: 12963974

2

A MEK inhibitor (U0126) markedly inhibits direct liver invasion of orthotopically inoculated human gallbladder cancer cells in nude mice.

Horiuchi H, Kawamata H, Furihata T, Omotehara F, Hori H, Shinagawa Y, Ohkura Y, Tachibana M, Yamazaki T, Ajiki T, Kuroda Y, Fujimori T. Horiuchi H, et al. J Exp Clin Cancer Res. 2004 Dec;23(4):599-606. J Exp Clin Cancer Res. 2004. PMID: 15743030

3

Susceptibility to cell death induced by blockade of MAPK pathway in human colorectal cancer cells carrying Ras mutations is dependent on p53 status.

Wang Z, Li Y, Liu ET, Yu Q. Wang Z, et al. Biochem Biophys Res Commun. 2004 Sep 17;322(2):609-13. doi: 10.1016/j.bbrc.2004.07.166. Biochem Biophys Res Commun. 2004. PMID: 15325273

4

[Establishment of liver metastasis model of human gallbladder cancer and isolation of the subpopulation with high metastatic potential].

Liu YB, He XW, Wang JW, Li JT, Li KQ, Liu FB, Xue JF, Zhu JH, Li B, Peng SY. Liu YB, et al. Zhonghua Yi Xue Za Zhi. 2006 Aug 15;86(30):2117-21. Zhonghua Yi Xue Za Zhi. 2006. PMID: 17064616 Chinese.

5

A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881

6

Vascular endothelial growth factor-D promotes growth, lymphangiogenesis and lymphatic metastasis in gallbladder cancer.

Lin W, Jiang L, Chen Y, She F, Han S, Zhu J, Zhou L, Tang N, Wang X, Li X. Lin W, et al. Cancer Lett. 2012 Jan 28;314(2):127-36. doi: 10.1016/j.canlet.2011.09.004. Epub 2011 Sep 22. Cancer Lett. 2012. PMID: 22071224

7

Differential sensitivity of chemoresistant neuroblastoma subtypes to MAPK-targeted treatment correlates with ERK, p53 expression, and signaling response to U0126.

Eppstein AC, Sandoval JA, Klein PJ, Woodruff HA, Grosfeld JL, Hickey RJ, Malkas LH, Schmidt CM. Eppstein AC, et al. J Pediatr Surg. 2006 Jan;41(1):252-9. doi: 10.1016/j.jpedsurg.2005.10.047. J Pediatr Surg. 2006. PMID: 16410143

8

Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

Andrieux L, Langouët S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A. Andrieux L, et al. Mol Pharmacol. 2004 Apr;65(4):934-43. doi: 10.1124/mol.65.4.934. Mol Pharmacol. 2004. PMID: 15044623

9

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo.

Bessard A, Frémin C, Ezan F, Fautrel A, Gailhouste L, Baffet G. Bessard A, et al. Oncogene. 2008 Sep 11;27(40):5315-25. doi: 10.1038/onc.2008.163. Epub 2008 Jun 2. Oncogene. 2008. PMID: 18521085

10

Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice.

Reyes G, Villanueva A, García C, Sancho FJ, Piulats J, Lluís F, Capellá G. Reyes G, et al. Cancer Res. 1996 Dec 15;56(24):5713-9. Cancer Res. 1996. PMID: 8971180

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