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Items: 1 to 20 of 160

1.
2.

Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.

Kokkinakis DM, Ahmed MM, Delgado R, Fruitwala MM, Mohiuddin M, Albores-Saavedra J.

Cancer Res. 1997 Dec 1;57(23):5360-8.

3.

O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics.

Silber JR, Bobola MS, Ghatan S, Blank A, Kolstoe DD, Berger MS.

Cancer Res. 1998 Mar 1;58(5):1068-73.

4.

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.

Kaina B, Christmann M, Naumann S, Roos WP.

DNA Repair (Amst). 2007 Aug 1;6(8):1079-99. Epub 2007 May 7. Review.

PMID:
17485253
5.

Activity of the DNA repair protein O6-methylguanine-DNA methyltransferase in human tumor and corresponding normal tissue.

Preuss I, Haas S, Eichhorn U, Eberhagen I, Kaufmann M, Beck T, Eibl RH, Dall P, Bauknecht T, Hengstler J, Wittig BM, Dippold W, Kaina B.

Cancer Detect Prev. 1996;20(2):130-6.

PMID:
8706038
6.

Evaluation of O6-methylguanine DNA methyltransferase activity in patients with gastric cancer.

Dinçer Y, Akçay T, Tortum OB, Alademir Z, Onen S, Doğusoy G.

Oncol Res. 2003;13(4):205-9.

PMID:
12659421
7.

Acquired resistance to 6-thioguanine in melanoma cells involves the repair enzyme O6-methylguanine-DNA methyltransferase (MGMT).

Gefen N, Brkic G, Galron D, Priel E, Ozer J, Benharroch D, Gopas J.

Cancer Biol Ther. 2010 Jan;9(1):49-55. Epub 2010 Jan 9.

PMID:
19946217
8.

O6-Methylguanine-DNA methyltransferase in pediatric primary brain tumors: relation to patient and tumor characteristics.

Bobola MS, Berger MS, Ellenbogen RG, Roberts TS, Geyer JR, Silber JR.

Clin Cancer Res. 2001 Mar;7(3):613-9.

9.

Repair of DNA lesion O6-methylguanine in hepatocellular carcinogenesis.

Major GN, Collier JD.

J Hepatobiliary Pancreat Surg. 1998;5(4):355-66. Review.

PMID:
9931384
10.

DNA repair in resistance to alkylating anticancer drugs.

Kaina B, Christmann M.

Int J Clin Pharmacol Ther. 2002 Aug;40(8):354-67. Review.

PMID:
12467304
11.
12.

O6-methylguanine-DNA methyltransferase activity in human liver tumors.

Isowa G, Ishizaki K, Sadamoto T, Tanaka K, Yamaoka Y, Ozawa K, Ikenaga M.

Carcinogenesis. 1991 Jul;12(7):1313-7.

PMID:
2070498
13.

Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.

Hermes M, Geisler H, Osswald H, Riehle R, Kloor D.

Biochem Pharmacol. 2008 Jun 1;75(11):2100-11. doi: 10.1016/j.bcp.2008.02.031. Epub 2008 Mar 8.

PMID:
18395186
14.

A methylation-specific and SYBR-green-based quantitative polymerase chain reaction technique for O6-methylguanine DNA methyltransferase promoter methylation analysis.

Hattermann K, Mehdorn HM, Mentlein R, Schultka S, Held-Feindt J.

Anal Biochem. 2008 Jun 1;377(1):62-71. doi: 10.1016/j.ab.2008.03.014. Epub 2008 Mar 14.

PMID:
18384736
15.

Change in expression of MGMT during maturation of human monocytes into dendritic cells.

Briegert M, Enk AH, Kaina B.

DNA Repair (Amst). 2007 Sep 1;6(9):1255-63. Epub 2007 Mar 26.

PMID:
17382605
16.

Amplification of the DNA repair gene O6-methylguanine-DNA methyltransferase associated with resistance to alkylating drugs in a mammalian cell line.

Tano K, Dunn WC, Darroudi F, Shiota S, Preston RJ, Natarajan AT, Mitra S.

J Biol Chem. 1997 May 16;272(20):13250-4.

17.

Targeted modulation of MGMT: clinical implications.

Liu L, Gerson SL.

Clin Cancer Res. 2006 Jan 15;12(2):328-31. Review.

18.

In situ detection of O6-methylguanine-DNA methyltransferase messenger RNA in paraffin-embedded human astrocytic tumor tissues by nested in situ RT-PCR is useful in predicting chemotherapy-resistance of tumors.

Ohe N, Saio M, Kijima M, Tamakawa N, Suwa T, Kojima Y, Yano H, Kaku Y, Iwama T, Shinoda J, Sakai N, Takami T.

Int J Oncol. 2003 Mar;22(3):543-9.

PMID:
12579307
19.

[Promoter hypermethylation of DNA repair gene O6-methylguanine DNA methyltransferase in laryngeal squamous cell carcinoma].

Zhang S, Kong WJ, Liu Z.

Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004 Mar;39(3):152-6. Chinese.

PMID:
15283294

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