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Genetics supersedes epigenetics in colon cancer phenotype.

Yamashita K, Dai T, Dai Y, Yamamoto F, Perucho M.

Cancer Cell. 2003 Aug;4(2):121-31.


CpG island methylator phenotype in colorectal cancer.

Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP.

Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6.


Characterization of mutator phenotype in familial colorectal cancer patients not fulfilling amsterdam criteria.

Kim JC, Lee KH, Ka IH, Koo KH, Roh SA, Kim HC, Yu CS, Kim TW, Chang HM, Gong GY, Kim JS.

Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6159-68.


Colorectal cancer "methylator phenotype": fact or artifact?

Anacleto C, Leopoldino AM, Rossi B, Soares FA, Lopes A, Rocha JC, Caballero O, Camargo AA, Simpson AJ, Pena SD.

Neoplasia. 2005 Apr;7(4):331-5.


Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer.

Deng G, Peng E, Gum J, Terdiman J, Sleisenger M, Kim YS.

Br J Cancer. 2002 Feb 12;86(4):574-9.


Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma.

An C, Choi IS, Yao JC, Worah S, Xie K, Mansfield PF, Ajani JA, Rashid A, Hamilton SR, Wu TT.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):656-63.


The epigenetics of colorectal cancer.

Issa JP.

Ann N Y Acad Sci. 2000 Jun;910:140-53; discussion 153-5.


Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.

Wheeler JM, Beck NE, Kim HC, Tomlinson IP, Mortensen NJ, Bodmer WF.

Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10296-301.


Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer.

Fox EJ, Leahy DT, Geraghty R, Mulcahy HE, Fennelly D, Hyland JM, O'Donoghue DP, Sheahan K.

J Mol Diagn. 2006 Feb;8(1):68-75.


Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer.

Nakagawa H, Chadwick RB, Peltomaki P, Plass C, Nakamura Y, de La Chapelle A.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):591-6. Epub 2000 Dec 19.


[Hypermethylation of hMLH1 promoter in sporadic colorectal cancer].

Song YM, Yuan Y, Zheng S.

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Sep;33(5):395-8. Chinese.


Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.

Konishi K, Shen L, Wang S, Meltzer SJ, Harpaz N, Issa JP.

Gastroenterology. 2007 Apr;132(4):1254-60. Epub 2007 Jan 25.


Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.

Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6870-5.


Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.

Toyota M, Ahuja N, Suzuki H, Itoh F, Ohe-Toyota M, Imai K, Baylin SB, Issa JP.

Cancer Res. 1999 Nov 1;59(21):5438-42.


Characterization of mutator pathway in younger-age-onset colorectal adenocarcinomas.

Roh SA, Kim HC, Kim JS, Kim JC.

J Korean Med Sci. 2003 Jun;18(3):387-91.


Heredity and DNA methylation in colorectal cancer.

Jass JR.

Gut. 2007 Jan;56(1):154-5. No abstract available.


DNA methylation in breast and colorectal cancers.

Samowitz WS, Ogino S.

Mod Pathol. 2008 Aug;21(8):1054; author reply 1054-5. doi: 10.1038/modpathol.2008.18. No abstract available.


A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.

Lind GE, Thorstensen L, Løvig T, Meling GI, Hamelin R, Rognum TO, Esteller M, Lothe RA.

Mol Cancer. 2004 Oct 11;3:28.

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