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Items: 1 to 20 of 130

1.

Nedd4 regulates egress of Ebola virus-like particles from host cells.

Yasuda J, Nakao M, Kawaoka Y, Shida H.

J Virol. 2003 Sep;77(18):9987-92.

2.
3.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.

Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2017 Sep 27;91(20). pii: e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15.

4.

Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.

Han Z, Lu J, Liu Y, Davis B, Lee MS, Olson MA, Ruthel G, Freedman BD, Schnell MJ, Wrobel JE, Reitz AB, Harty RN.

J Virol. 2014 Jul;88(13):7294-306. doi: 10.1128/JVI.00591-14. Epub 2014 Apr 16.

5.

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding.

Han Z, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2016 Sep 29;90(20):9163-71. doi: 10.1128/JVI.01078-16. Print 2016 Oct 15.

6.

Budding of PPxY-containing rhabdoviruses is not dependent on host proteins TGS101 and VPS4A.

Irie T, Licata JM, McGettigan JP, Schnell MJ, Harty RN.

J Virol. 2004 Mar;78(6):2657-65. Erratum in: J Virol. 2004 May;78(10):5532.

7.

ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.

Han Z, Madara JJ, Liu Y, Liu W, Ruthel G, Freedman BD, Harty RN.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S138-45. doi: 10.1093/infdis/jiu838. Epub 2015 Mar 18.

8.

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity.

Okumura A, Pitha PM, Harty RN.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3974-9. doi: 10.1073/pnas.0710629105. Epub 2008 Feb 27.

9.
10.

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jan 11;13(1):e1006132. doi: 10.1371/journal.ppat.1006132. eCollection 2017 Jan. Erratum in: PLoS Pathog. 2017 Jul 19;13(7):e1006519.

11.

Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4.

Timmins J, Schoehn G, Ricard-Blum S, Scianimanico S, Vernet T, Ruigrok RW, Weissenhorn W.

J Mol Biol. 2003 Feb 14;326(2):493-502.

PMID:
12559917
12.

Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding.

Yasuda J, Hunter E, Nakao M, Shida H.

EMBO Rep. 2002 Jul;3(7):636-40.

13.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.

Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG.

J Virol. 2015 Oct;89(20):10399-406. doi: 10.1128/JVI.01736-15. Epub 2015 Aug 5.

14.

Regulation of Marburg virus (MARV) budding by Nedd4.1: a different WW domain of Nedd4.1 is critical for binding to MARV and Ebola virus VP40.

Urata S, Yasuda J.

J Gen Virol. 2010 Jan;91(Pt 1):228-34. doi: 10.1099/vir.0.015495-0. Epub 2009 Oct 7.

PMID:
19812267
16.

Role of Nedd4 and ubiquitination of Rous sarcoma virus Gag in budding of virus-like particles from cells.

Vana ML, Tang Y, Chen A, Medina G, Carter C, Leis J.

J Virol. 2004 Dec;78(24):13943-53.

17.

PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected].

Bouamr F, Melillo JA, Wang MQ, Nagashima K, de Los Santos M, Rein A, Goff SP.

J Virol. 2003 Nov;77(22):11882-95. Erratum in: J Virol. 2004 Apr;78(8):4383.

18.

The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release.

Gottwein E, Bodem J, Müller B, Schmechel A, Zentgraf H, Kräusslich HG.

J Virol. 2003 Sep;77(17):9474-85.

19.

Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding.

Blot V, Perugi F, Gay B, Prévost MC, Briant L, Tangy F, Abriel H, Staub O, Dokhélar MC, Pique C.

J Cell Sci. 2004 May 1;117(Pt 11):2357-67.

20.

Tsg101 can replace Nedd4 function in ASV Gag release but not membrane targeting.

Medina G, Pincetic A, Ehrlich LS, Zhang Y, Tang Y, Leis J, Carter CA.

Virology. 2008 Jul 20;377(1):30-8. doi: 10.1016/j.virol.2008.04.024.

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